A deeper understanding of the mechanisms underlying autism spectrum disorders or potential therapeutic approaches will require investigation at multiple levels, including but not limited to studies focused on gene discovery, molecular mechanisms, circuits, anatomy, and cognition and behavior. We will consider proposals at all of these levels.
Grants awarded through the Bridge to Independence Award program are intended to invest in the next generation of top autism investigators by identifying talented early-career scientists interested in autism research and facilitating their transition to an independent research career. This request for applications is aimed at senior postdoctoral fellows who intend to seek tenure-track faculty positions during the 2017-18 academic year. Successful applicants will receive a commitment of $150,000 per year for three years, to be used for an autism-relevant project, activated upon assumption of a tenure-track professorship.
We seek applications from independent investigators who will conduct bold, imaginative, and rigorous research to improve the understanding, diagnosis and treatment of autism spectrum disorders. Applications can include, but are not limited to, studies at the genetic, molecular, cellular, circuit and behavioral levels, in addition to clinical and translational studies. Two types of applications are available: the SFARI Pilot Award and the SFARI Research Award.
Grants awarded through this request are intended to support a network of U.S.-based clinical sites to recruit individuals and families affected by autism spectrum disorders (ASD) to participate in SPARK. The overall goals of SPARK are to recruit, engage and retain a community of 50,000 individuals with ASD, along with their family members in the United States. This research cohort will include children and adults with ASD, who span the full spectrum of autism and include individuals of all socio-demographic backgrounds. Selected clinical sites will receive funding of up to $150,000/year for a maximum of three years.
Grants awarded through this request for applications (RFA) are intended to develop and validate objective outcome measures for use in clinical trials targeting core symptoms (social communication impairments and restricted, repetitive behaviors) of autism spectrum disorder, and disruptive behavioral symptoms commonly reported in individuals with autism (e.g., anxiety, tantrums).
Grants awarded through this request for applications (RFA) are intended to advance our understanding of the genetic basis of autism, and in particular the potential role of missense and in-frame deletion variants in conferring risk.
Grants awarded through this Request for Applications (RFA) are intended to advance our understanding of the impact of activation of the innate immune system on behavioral, circuit, synaptic and neuronal functions in order to understand the consequences of infection and immune activation on autism-related behaviors.
Grants awarded through this request for applications (RFA) are intended to advance our understanding of the genetic basis of autism, and in particular, to begin to assess genetic variants conferring risk in non-coding regions and in coding regions of the genome that may be less accessible to whole-exome sequencing. Investigators who are interested in developing innovative and efficient ways to analyze whole-genome sequencing data from 500 Simons Simplex Collection (SSC) families are encouraged to apply. The maximum budget is $250,000, including indirect costs, for eighteen months, non-renewable.