Life Sciences lectures are open to the public and are held at the Gerald D. Fischbach Auditorium at the Simons Foundation headquarters in New York City. Tea is served prior to each lecture.
In this lecture, Arnold Levine will discuss how recent studies have illuminated a great deal about the human immune system and its complexities. Methods for sequencing T cell receptors and quantifying their diversity have been developed. Antigens recognized by these T cell receptors can be identified by matching amino acid sequences to mutations in the DNA sequences of cancers and the microbiome. Algorithms are being developed to identify responders and non-responders, identify tumor antigens and explore the vitality and functionality of the immune system.