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  • Building Biological Intelligence Investigating how the ingredients of biological computation come together to produce a system vastly more powerful than its constituent parts

    Computational Vision Developing novel computational methods to study how the brain analyzes and represents visual information.

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Computational Neuroscience

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    Building Biological Intelligence Investigating how the ingredients of biological computation come together to produce a system vastly more powerful than its constituent parts

    Computational Vision Developing novel computational methods to study how the brain analyzes and represents visual information.

    High Dimensional Dynamics and Computation Developing theories linking synaptic connectivity, neuronal dynamics and computation.

    Information Processing in Neural Networks Investigating the dynamics, statistical properties and principles of information processing in biological neural circuits and artificial neural networks.

    Neural Circuits and Algorithms Studying how the brain processes complex sensory data to inform AI networks and mental health treatments.

    NeuroRSE Building open source software for computational and systems neuroscience.

    Statistical Analysis of Neural Data Developing statistical models and computational tools to extract insights from neural data.

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Flatiron Institute Computational Neuroscience

Computational Neuroscience: Publications

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  1. Perpetual step-like restructuring of hippocampal circuit dynamics

    Cell Reports, bioRxiv:2024.04.22.590576v1, September 24, 2024

    S. Zheng, Roman Huszár, Thomas Hainmueller, Marlene Bartos, A. Williams, and György Buzsáki

  2. Mapping models of V1 and V2 selectivity with local spectral reverse correlation

    Journal of Vision, September 15, 2024

    T. Oleskiw , Ramanujan Raghavan, Justin Lieber, E. Simoncelli, and J. Movshon

  3. Fixational eye movements enhance the precision of visual information transmitted by the primate retina

    Nature Communications, bioRxiv:2023.08.12.552902, September 11, 2024

    Eric G. Wu, Nora Brackbill, Colleen Rhoades, Alexandra Kling, Alex R. Gogliettino, Nishal P. Shah, et al.

  4. Natural Image Densities: Learning, Understanding and Utilizing

    New York University ProQuest Dissertations & Theses, September 1, 2024

  5. Visual Temporal Prediction: Representation, Estimation, and Modeling

    New York University ProQuest Dissertations & Theses, September 1, 2024

    P. Fiquet

  6. Geometric changes in monkey V4 and IT neural responses during visual category learning

    Journal of Vision, September 1, 2024

    J. Feather, Long Sha, Gouki Okazawa, N. Yu Lo, S. Chung, and R. Kiani

  7. Tensor Decomposition Meets RKHS: Efficient Algorithms for Smooth and Misaligned Data

    arXiv:2408.05677, August 11, 2024

    B. Larsen, Tamara G. Kolda, Anru R. Zhang, and A. Williams

  8. Neuronal and behavioral responses to naturalistic texture images in macaque monkeys

    The Journal of Neuroscience, bioRxiv 2024.02.22.581645, 2024

    C M Ziemba, R L T Goris, G M Stine, R K Perez, E. Simoncelli, and J A Movshon

  9. Context-invariant beliefs are supported by dynamic reconfiguration of single unit functional connectivity in prefrontal cortex of male macaques

    Nature Communications, bioRxiv:2023.07.30.551169, July 9, 2024

    Jean-Paul Noel, E. Balzani, Cristina Savin, and D. Angelaki

  10. The neuron as a direct data-driven controller

    Proceedings of the National Academy of Sciences of the United States of America, arXiv:2401.01489, June 24, 2024

    J. Moore, A. Genkin, Magnus Tournoy, J. Pughe-Sanford, Rob R. de Ruyter van Steveninck, and D. Chklovskii

  11. Privileged representational axes in biological and artificial neural networks

    bioRxiv:2024.06.20.599957, June 20, 2024

    Meenakshi Khosla, A. Williams, Josh McDermott, and N. Kanwisher

  12. Disparate nonlinear neural dynamics measured with different techniques in macaque and human V1

    Scientific Reports, June 8, 2024

    J. Zhou, Matt Whitmire, Yuzhi Chen, and Eyal Seidemann

  13. Layerwise complexity-matched learning yields an improved model of cortical area {V2}

    Trans. Machine Learning Research, arXiv: 2312.11436, 2024

    N. Parthasarathy, O J Henaff, and E. Simoncelli

  14. HybridBNN: Joint Training of Deterministic and Stochastic Layers in Bayesian Neural Nets

    Sixth Symposium on Advances in Approximate Bayesian Inference - Non Archival Track, May 27, 2024

    A. Nejatbakhsh and Julien Boussard

  15. Optimal compressed sensing for image reconstruction with diffusion probabilistic models

    Transactions on Machine Learning, arXiv:2405.17456, May 22, 2024

    Ling-Qi Zhang, Z. Kadkhodaie, E. Simoncelli, and D. Brainard

  16. Versatile multiple object tracking in sparse 2D/3D videos via deformable image registration

    PLOS Computational Biology, bioRxiv:2022.07.18.500485v1, May 20, 2024

    James Ryu, A. Nejatbakhsh, Mahdi Torkashvand, Sahana Gangadharan, Maedeh Seyedolmohadesin, Jinmahn Kim, et al.

  17. A unified framework for perceived magnitude and discriminability of sensory stimuli

    Proceedings of the National Academy of Sciences of the United States of America, bioXriv:2022.04.30.490146v3, April 25, 2024

    J. Zhou, L. Duong, and E. Simoncelli

  18. Estimating Shape Distances on Neural Representations with Limited Samples

    The Twelfth International Conference on Learning Representations, arXiv:2310.05742, March 15, 2024

    Dean A. Pospisil, B. Larsen, S. Harvey, and A. Williams

  19. Towards an Improved Understanding and Utilization of Maximum Manifold Capacity Representations

    ICLR 2024 Workshop on Mathematical and Empirical Understanding of Foundation Models, arXiv:2406.09366, March 4, 2024

    Rylan Schaeffer, Berivan Isik, Dhruv Bhandarkar Pai, Andres Carranza, Victor Lecomte, Alyssa Unell, et al.

  20. Disentangling Recurrent Neural Dynamics with Stochastic Representational Geometry

    ICLR 2024 Workshop on Representational Alignment, March 2, 2024

    D. Lipshutz, A. Nejatbakhsh, and A. Williams

  21. On the universality of neural encodings in CNNs

    ICLR 2024 Workshop on Representational Alignment, arXiv:2409.19460, March 2, 2024

    F. Guth and Brice Ménard

  22. Neural Manifold Capacity Captures Representation Geometry, Correlations, and Task-Efficiency Across Species and Behaviors

    bioRxiv:2024.02.26.582157v1, February 28, 2024

    C. Chou, Luke Arend, Albert J. Wakhloo, Royoung Kim, Will Slatton, and S. Chung

  23. Neuronal Temporal Filters as Normal Mode Extractors

    Physical Review Research, arXiv:2401.03248, January 29, 2024

    S. Golkar, J. Berman, D. Lipshutz, Robert Mihai Haret, Tim Gollisch, and D. Chklovskii

  24. Complex priors and flexible inference in recurrent circuits with dendritic nonlinearities

    The Twelfth International Conference on Learning Representations, bioRxiv:2023.10.03.560701, January 16, 2024

    Benjamin S. H. Lyo and Cristina Savin

  25. Generalization in diffusion models arises from geometry-adaptive harmonic representations

    The Twelfth International Conference on Learning Representations, arXiv:2310.02557, January 16, 2024

    Z. Kadkhodaie, F. Guth, E. Simoncelli, and S. Mallat

  26. Probing Biological and Artificial Neural Networks with Task-dependent Neural Manifolds

    Conference on Parsimony and Learning, PMLR, arXiv:2312.14285, January 6, 2024

    Michael Kuoch, C. Chou, N. Parthasarathy, Joel Dapello, J. DiCarlo, H. Sompolinsky, et al.

  27. Comparing neural models using their perceptual discriminability predictions

    Advances in Neural Information Processing Systems, 2023

    J. Zhou, Chanwoo Chun, Ajay Subramanian, and E. Simoncelli

  28. Efficient coding of natural images using maximum manifold capacity representations

    Advances in Neural Information Processing Systems, 2023

    Yilun Kuang, E. Simoncelli, and S. Chung

  29. Adaptive whitening with fast gain modulation and slow synaptic plasticity

    Advances in Neural Information Processing Systems, 2023

    L. Duong, E. Simoncelli, D. Chklovskii, and D. Lipshutz

  30. A polar prediction model for learning to represent visual transformations

    Advances in Neural Information Processing Systems, 2023

    P. Fiquet and E. Simoncelli

  31. Targeted V1 comodulation supports task-adaptive sensory decisions

    Nature Communications, 2023

    Caroline Haimerl, Douglas A. Ruff, Marlene Cohen, Cristina Savin, and E. Simoncelli

  32. Spatiotemporal Clustering with Neyman-Scott Processes via Connections to Bayesian Nonparametric Mixture Models

    Journal of the American Statistical Association, November 9, 2023

    Yixin Wang, Anthony Degleris, A. Williams, and Scott W. Linderman

  33. Foveated metamers of the early visual system

    eLife, bioRxiv 2023.05.18.541306, 2023

    B. Broderick, G Rufo, J Winawer, and E. Simoncelli

  34. Neural network adaptive coding efficiency and stochastic representational geometry

    Dissertation, 2023

    L. Duong

  35. Normative framework for deriving neural networks with multi-compartmental neurons and non-Hebbian plasticity

    arXiv:2302.10051, 2023

    D. Lipshutz, Y. Bahroun, S. Golkar, A. Sengupta, and D. Chklovskii

  36. Unlocking the Potential of Similarity Matching: Scalability, Supervision and Pre-training

    International Conference on Machine Learning, 2023

    Y. Bahroun, Shagesh Sridharan, Atithi Acharya, D. Chklovskii, and A. Sengupta

  37. Learning multi-scale local conditional probability models of images

    International Conference on Learning Representations, 2023

    Z. Kadkhodaie, F. Guth, S. Mallat, and E. Simoncelli

  38. Spatial frequency selectivity in macaque LGN and V1

    Dissertation, 2023

    Paul Levy

  39. Catalyzing next-generation [Artificial Intelligence} through {NeuroAI}

    Nature Communications, 2023

    A Zador, S Escola, B Richards, B Ölveczky, Y Bengio, K Baohen, et al.

  40. Catalyzing next-generation Artificial Intelligence through NeuroAI

    Nature Communications, 2023

    Anthony Zador, Sean Escola, Blake Richards, Bence Ölveczky, Yoshua Bengio, Kwabena Boahen, et al.

  41. Polar prediction of natural videos

    arXiv:2303.03432, 2023

    P. Fiquet and E. Simoncelli

  42. Coordinated drift of receptive fields in Hebbian/anti-Hebbian network models during noisy representation learning

    Nature Neuroscience, bioRxiv:2021.08.30.458264v1, 2023

    Shanshan Qin, S. Farashahi, D. Lipshutz, A. Sengupta, D. Chklovskii, and Cengiz Pehlevan

  43. Fine-tuning hierarchical circuits through learned stochastic co-modulation

    Advances in Neural Information Processing Systems, 2022

    E. Simoncelli and Cristina Savin

  44. Maximum a posteriori natural scenes reconstruction from retinal ganglion cells with deep denoiser priors

    Advances in Neural Information Processing Systems, 2022

    Eric G. Wu, Nora Brackbill, Alexander Sher & Alan M. Litke, E. Simoncelli, and E.J. Chichilnisky

  45. Normative theories of synaptic plasticity for representation and perceptual discrimination

    Dissertation, 2022

    Colin Bredenberg

  46. Neural Circuits for Dynamics-Based Segmentation of Time Serie

    Neural Computation, 2022

    T. Tesileanu, S. Golkar, Samaneh Nasiri, A. Sengupta, and D. Chklovskii

  47. Deep denoising for scientific discovery: A case study in electron microscopy

    IEEE Transactions on Computational Imaging, 2022

    S. Mohan, Ramon Manzorro, Joshua L. Vincent, Binh Tang, Dev Y. Sheth, E. Simoncelli, et al.

  48. Robust and interpretable denoising via deep learning

    Dissertation, 2022

    S. Mohan

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