The mission of the Flatiron Institute is to advance scientific research through computational methods, including data analysis, theory, modeling and simulation.

Simons Foundation

Featured News

Center for Computational Astrophysics Magnetic ‘Balding’ of Black Holes Saves General Relativity Prediction By Thomas Sumner

Magnetic fields around black holes decay quickly, report researchers from the Flatiron Institute, Columbia University and Princeton University. This finding backs up the so-called ‘no-hair conjecture’ predicted by Einstein’s general relativity.

Center for Computational Quantum Physics Ultrafast Microscope Observes Quick-Moving Excitation That Could Be a Long Sought Phase of Matter

Center for Computational Biology HumanBase Sees Connections Between COVID-19 and Diabetes

Our Centers

Center for Computational Astrophysics

Center for Computational Biology

Center for Computational Mathematics

Center for Computational Neuroscience

Center for Computational Quantum Physics

Scientific Computing Core

It develops, deploys and maintains computational infrastructure — from supercomputers to desktop PCs — dedicated solely to the use of Flatiron researchers.

Flatiron Institute Inclusion, Diversity,
Equity & Advocacy (IDEA) Scholar Program

For distinguished scientists with a particular interest in diversity and inclusion

Scholars may engage in a variety of activities, such as working on scientific projects, starting new collaborations, mentoring junior scientists, and organizing or participating in workshops and career development events.

Learn More

A major effort of the Flatiron Institute is the development and support of high-quality, open-source software for research.

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Research Highlights

June 24, 2021

Experiences and lessons learned from two virtual, hands-on microbiome bioinformatics workshops

Matthew R Dillon, Evan Bolyen, Anja Adamov, J. Morton, R. Bonneau, et al.

In October of 2020, in response to the Coronavirus Disease 2019 (COVID-19) pandemic, our team hosted our first fully online…

PLOS Comuptational Biology

June 8, 2021

Temporal integration of inductive cues on the way to gastrulation

Sarah McFann, Sayantan Dutta, Jared E. Toettcher, S. Shvartsman

In early development, cells commit to a single germ fate despite receiving multiple, conflicting inductive cues. Here, we examine how…

Proceedings of the National Academy of Science of the USA

June 7, 2021

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Parisa Hosseinzadeh, Paris R. Watson, Timothy W. Craven, V. Mulligan, et al.

Despite recent success in computational design of structured cyclic peptides, de novo design of cyclic peptides that bind to any…

Nature Communications

News & Announcements

Visualizing Science

July 27, 2021

Visualizing Science: When Galaxies Collide

Center for Computational Astrophysics

July 27, 2021

Magnetic ‘Balding’ of Black Holes Saves General Relativity Prediction By Thomas Sumner

Center for Computational Quantum Physics

July 21, 2021

Ultrafast Microscope Observes Quick-Moving Excitation That Could Be a Long Sought Phase of Matter

Leadership

Leslie Greengard, M.D., Ph.D.

Director, CCM

Leslie Greengard joined the Simons Foundation in 2013 as founding director of the Simons Center for Data Analysis, now called the Center for Computational Biology. Prior to that, Greengard served as director of the Courant Institute of Mathematical Sciences at New York University.

Nick Carriero, Ph.D.

Co-Director, SCC

Nick Carriero came to the Simons Foundation in 2014 from Yale University, where he was a senior research scientist in computer science and co-director of the W.M. Keck Biotechnology Resource Laboratory’s high-performance computing resource.

Ian Fisk, Ph.D.

Co-Director, SCC

Ian Fisk came to the Simons Foundation in 2014 after working in the computing division at the Fermi National Accelerator Laboratory in Illinois since 2003. Fisk was the Compact Muon Solenoid (CMS) experiment’s computing coordinator at CERN from 2010 to 2013, overseeing operations and improvements…

Antoine Georges, Ph.D.

Director, CCQ

Antoine Georges is a professor of physics at the Collège de France, where he holds the chair in condensed matter physics. He also has joint appointments with École Polytechnique and the University of Geneva. He received his Ph.D. from the École Normale Supérieure in 1988.…

Shirley Ho, Ph.D.

Interim Director, CCA

Shirley Ho joined the foundation in 2018 as leader of the Cosmology X Data Science group at CCA and In 2021, she assumed the role of CCA’s interim director.

Andrew Millis, Ph.D.

Co-Director, CCQ

Andrew Millis is co-director of the Center for Computational Quantum Physics and associate director for Physics at the Simons Foundation. He has done fundamental research on heavy fermion compounds, quantum phase transitions, ‘colossal’ magnetoresistance materials and high transition-temperature superconductivity.

Michael Shelley, Ph.D.

Director, CCB

Michael Shelley joined the Simons Foundation in 2016 to work on the modeling and simulation of complex systems arising in physics and biology.

Eero P. Simoncelli, Ph.D.

Director, CCN

Eero P. Simoncelli is the inaugural director of the Center for Computational Neuroscience. Eero P. Simoncelli’s research interests span a wide range of topics in the representation and analysis of visual images and sounds in both machine and biological vision systems.