The mission of the Flatiron Institute is to advance scientific research through computational methods, including data analysis, theory, modeling and simulation.

Simons Foundation

Featured News

Center for Computational Biology NetQuilt: A Powerful Computational Approach for Predicting Protein Function By Susan Reslewic Keatley, Ph.D.

By stitching together an unprecedented diversity of data, a new software platform has enabled scientists to robustly predict what proteins do.

Center for Computational Quantum Physics Ultrafast Microscope Observes Quick-Moving Excitation That Could Be a Long Sought Phase of Matter

Center for Computational Astrophysics Cracking a Mystery of Massive Black Holes and Quasars with Supercomputer Simulations

Our Centers

Center for Computational Astrophysics

Center for Computational Biology

Center for Computational Mathematics

Center for Computational Neuroscience

Center for Computational Quantum Physics

Scientific Computing Core

It develops, deploys and maintains computational infrastructure — from supercomputers to desktop PCs — dedicated solely to the use of Flatiron researchers.

Flatiron Institute Inclusion, Diversity,
Equity & Advocacy (IDEA) Scholar Program

For distinguished scientists with a particular interest in diversity and inclusion

Scholars may engage in a variety of activities, such as working on scientific projects, starting new collaborations, mentoring junior scientists, and organizing or participating in workshops and career development events.

Learn More

A major effort of the Flatiron Institute is the development and support of high-quality, open-source software for research.

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Research Highlights

January 20, 2022

SARS-CoV-2 RNA concentrations in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases

Fuqing Wu, Amy Xiao, R. Bonneau, et al.

Current estimates of COVID-19 prevalence are largely based on symptomatic, clinically diagnosed cases. The existence of a large number of…

Science of The Total Environment

January 1, 2022

Robust regression with compositional covariates

A. Mishra, C. Müller

Many high-throughput sequencing data sets in biology are compositional in nature. A prominent example is microbiome profiling data, including targeted…

Computational Statistics & Data Analysis

November 3, 2021

Encoding Priors with Group Sparsity for Model Learning From Limited and Noisy Biological Data

Suryanarayana Maddu, Dominik Sturm, Bevan L Cheeseman, C. Müller, Ivo F Sbalzarini

Numerical methods for approximately solving partial differential equations (PDE) are at the core of scientific computing. Often, this requires high-resolution…

14th WCCM & ECCOMAS Congress 2020

News & Announcements

Center for Computational Astrophysics

October 15, 2021

Astrophysicist Blakesley Burkhart Receives American Physical Society’s Maria Goeppert Mayer Award

Center for Computational Biology

October 05, 2021

NetQuilt: A Powerful Computational Approach for Predicting Protein Function By Susan Reslewic Keatley, Ph.D.

Center for Computational Mathematics

September 21, 2021

Computational Chemist Erik Thiede Named a Finalist for Blavatnik Regional Award for Young Scientists

Leadership

Leslie Greengard, M.D., Ph.D.

Director, CCM

Leslie Greengard joined the Simons Foundation in 2013 as founding director of the Simons Center for Data Analysis, now called the Center for Computational Biology. Prior to that, Greengard served as director of the Courant Institute of Mathematical Sciences at New York University.

Nick Carriero, Ph.D.

Co-Director, SCC

Nick Carriero came to the Simons Foundation in 2014 from Yale University, where he was a senior research scientist in computer science and co-director of the W.M. Keck Biotechnology Resource Laboratory’s high-performance computing resource.

Julianne Dalcanton, Ph.D.

Director, CCA

Julianne Dalcanton joined the Simons Foundation in September 2021 as the director of the Flatiron Institute’s Center for Computational Astrophysics (CCA). Her research specializes in the origins and evolution of galaxies.

Ian Fisk, Ph.D.

Co-Director, SCC

Ian Fisk came to the Simons Foundation in 2014 after working in the computing division at the Fermi National Accelerator Laboratory in Illinois since 2003. Fisk was the Compact Muon Solenoid (CMS) experiment’s computing coordinator at CERN from 2010 to 2013, overseeing operations and improvements…

Antoine Georges, Ph.D.

Director, CCQ

Antoine Georges is a professor of physics at the Collège de France, where he holds the chair in condensed matter physics. He also has joint appointments with École Polytechnique and the University of Geneva. He received his Ph.D. from the École Normale Supérieure in 1988.…

Andrew Millis, Ph.D.

Collaboration Director

Andrew Millis is co-director of the Center for Computational Quantum Physics and associate director for Physics at the Simons Foundation. He has done fundamental research on heavy fermion compounds, quantum phase transitions, ‘colossal’ magnetoresistance materials and high transition-temperature superconductivity.

Michael Shelley, Ph.D.

Director, CCB

Michael Shelley joined the Simons Foundation in 2016 to work on the modeling and simulation of complex systems arising in physics and biology.

Eero P. Simoncelli, Ph.D.

Director, CCN

Eero P. Simoncelli is the inaugural director of the Center for Computational Neuroscience. Eero P. Simoncelli’s research interests span a wide range of topics in the representation and analysis of visual images and sounds in both machine and biological vision systems.