Center for Computational Biology

We push the boundaries of biological inquiry by integrating theory, computation and experimentation.

Drosophila tracheal terminal cell. We can customize this image caption to further describe CCB’s mission and goals… iSO-FORM LLC/Lucy Reading-Ikkanda/Simons Foundation

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About

Over the past fifty years, the field of biology has transformed from a predominantly empirical science into one grounded in quantitative theory, modern tools of data analysis, and large-scale simulation.

Our research teams have access to the state-of-the-art computing power they need to undertake ambitious, long-term research projects that transcend conventional disciplinary boundaries. Our goal is to advance a quantitative and predictive understanding of biological phenomena.

We develop rigorous modeling tools and theory to characterize biological processes and to create computational frameworks that will enable the analysis of the large, complex datasets being generated by quantitative experimental technologies.

Latest News

Stylized illustration of sperm tails coiled up and aligned tidily.

Mysteries of Fruit Fly Sperm Untangled by Mathematical Models

protein structure

Beyond the Cryo-EM Resolution Revolution

Photo of three people with trees behind them.

How Mathematical Modeling Identified Subclasses of Autism

Upcoming Events

Unraveling Bacterial Swimming: Insights from Mathematical Modeling, Simulations, and Experiments

Seminar

October 16, 2026

11 a.m.–12 p.m. ET

Speaker

Sookkyung Lim, Ph.D.

From Cryo-EM Structures to AI-Powered Predictions of Amyloid Formation

Seminar

October 29, 2026

11 a.m.–12 p.m. ET

Speaker

Andrey Kajava, Ph.D.

Events

Job Openings

Posted
Section
Computational Biology
About
The Center for Computational Biology (CCB) of the Simons Foundation’s Flatiron Institute is actively seeking enthusiastic, full-time post-doctoral Flatiron Research Fellows to join its Developmental Dynamics Group. Candidates interested in data-driven modeling of biological systems, especially in the context of behavioral changes during postembryo…
Posted
Section
Computational Biology
For
Postdoctoral Researcher
Area
Research/Science
About
The Center for Computational Biology(CCB), an in-house research center of the Simons Foundation’s Flatiron Institute, is actively seeking enthusiastic, full-time post-doctoral Flatiron Research Fellows to join its Biological Transport & Networks Group.  The start date is flexible, with the Fellow expected to begin no later than September 2027. App…

Contact Us

Flatiron Institute
162 5th Ave.
New York, NY 10010

Visitors must first contact us.

Phone: 646.654.0066
Fax: 646.654.0220

For more information about Center for Computational Biology research, people, and events, please contact [email protected].