Funded Work

The Simons Society of Fellows is a community of scholars that encourages intellectual interactions across disciplines and across research centers in the New York City area.

Among the multiple cognitive processes that are atypical in people with autism, attention stands out as one of the most important.

In the current project, Paul Dudchenko provides a detailed neural and behavioral characterization of three rat models of autism spectrum disorder/intellectual disability (ASD/ID): Fmr1-/y, Grin2b …

Autism spectrum disorder (ASD), a chronic and heterogeneous condition with many traits and co-occurring conditions, is poorly understood.

In work that began nearly 15 years ago, Daniel Geschwind and collaborators identified a shared pattern of transcriptomic and epigenetic dysregulation in postmortem brain tissue of people with …

Gut disturbances are unusually common in individuals with autism spectrum disorder (ASD), but the basis of these gut irregularities is not yet known.

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental condition with core characteristics that are broadly categorized as problems with social engagement that are proposed, in part, to emanate …

More than 90 percent of individuals diagnosed with autism spectrum disorder (ASD) exhibit sensory alterations, with 60 percent displaying altered tactile sensitivity.

The goal of this project is to investigate genes that increase risk for autism spectrum disorder (ASD) by characterizing mutant zebrafish.

Math organization that helps schools and school districts create a middle and high school pathway for success in advanced mathematics.

Integrating art, science and nature and broadening participation through public engagement, outreach, activism and public art.

On-deadline service connecting reporters to expert sources and research-backed evidence for use in their stories.

Community based organization creating a science learning initiative dedicated to engaging Spanish speaking immigrants and their children with New York City math and science learning institutions.

Math museum providing math enrichment activities for students that parents can replicate at home.

Axon pathology is at the core of disruptions in cortical connectivity in autism spectrum disorder (ASD).

White matter tracts are understudied brain regions with respect to the pathophysiology of autism spectrum disorder (ASD).

Autism spectrum disorder (ASD) has a large genetic component, but the underlying cause of ASD has not been identified in most affected individuals.

Motor impairments, from altered coordination to reduced flexibility of movements, are among the core features of autism spectrum disorder (ASD).

The last four decades have produced an enormous catalog of human genomic variants which has the potential to revolutionize human genetics.

Capturing variation in behavioral phenotypes expressed across rodent models of autism spectrum disorder (ASD) remains a challenge.

Our ability to learn, remember and make decisions changes with age.

Atypical sensory experiences affect around 90 percent of individuals with autism spectrum disorder (ASD).

Many cases of autism spectrum disorder (ASD) are caused by reduced expression of dosage-sensitive genes.

During early postnatal development, many neocortical brain areas exhibit “sensitive periods” where circuit refinement is driven by experience, by engaging both Hebbian (correlation-based) and homeostatic forms of …

Challenges in social communication are one of the core symptoms of autism spectrum disorder (ASD).

This project takes advantage of the rat as a model system to parse the role of striatal dopamine in social behaviors, specifically probing whether and how dysfunction in …

Funding student fellowships and programming at the Initiative for the Theoretical Sciences. The Initiative for the Theoretical Sciences at the CUNY Graduate Center endeavors to develop concise and …

A new Astrophysics master’s program designed to prepare students from all backgrounds to excel in astronomy and physics doctoral programs as well as STEM careers. With the …

An annual, three-day meeting that encourages students to pursue advanced degrees in mathematics and mathematics education. The conference is geared toward undergraduates from Historically Black Colleges and …

A program to help train the next generation of science, technology, engineering and mathematics leaders. With the Simons Foundation’s $56.6 million gift, the Stony Brook Simons …

To advance our understanding of autism spectrum disorder (ASD) and to develop novel therapeutics, it is critical to understand how genetic and cellular changes lead to changes in …

Through the sequencing efforts of the Simons Simplex Collection (SSC), Simons Foundation Powering Autism Research (SPARK) and Autism Sequencing Consortium (ASC), thousands of de novo coding mutations have …

Los Angeles-based organization combining innovation, transformation, and democratization to reimagine education and create systemic change.

Organization amplifying youth and community power by inspiring, guiding and advocating for youth to determine their college, career and leadership futures.

Education design company creating high-quality summer learning and out-of-school time opportunities for highly motivated yet historically excluded BIPOC students.

Organization that aims to inspire and deepen the public’s ability to critically think about the social origins of global warming and environmental change.

Stellarators are very promising magnetic fusion energy confinement devices.

How does sleep sustain synaptic lipid function across life?

The world’s population is rapidly aging.

Sleep problems occur at a higher rate in people with autism spectrum disorder (ASD), affecting up to 93 percent of people with ASD.

It is unknown how the COVID-19 pandemic affects pregnant women and their offspring.

Reciprocal cooperation is a hallmark of social groups and is central to successful social interaction, playing a major role in evolutionarily shaping brain functions and enabling rich social …

Altered sensory processing is a core and predictive feature of autism spectrum disorder (ASD).

Individuals with autism spectrum disorder (ASD) perceive and experience the world differently than neurotypical individuals.

Like many complexly inherited conditions, autism shows high heritability, yet the inventory of identified genomic variants appears to explain only a modest portion of the risk.