Plasticity and the Aging Brain
The Simons Collaboration on Plasticity and the Aging Brain aims to discover mechanisms of resilience and maintenance in the aging brain and to establish a baseline for age-related changes in plasticity across many model systems, in order to identify potential interventions to minimize cognitive decline and extend healthy lifespan.
Events & Lectures
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SCPAB Simons Foundation Autism and Neuroscience SfN Social
All Society for Neuroscience annual meeting attendees are welcome to join Simons Investigators and scientific staff from the Simons Foundation Autism Research Initiative (SFARI), Smons Collaboration on the Global Brain (SCGB), and Simons Collaboration on Plasticity and the Aging Brain (SCPAB) for an evening of socializing and updates.
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Research Highlights
Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes
F Rapino, T Natoli, F Limone, E O'Connor, J Blank, M Tegtmeyer, W Chen, E Norabuena, J Narula, D Hazelbaker, G Angelini, L Barrett, A O'Neil, UK Beattie, JM Thanos, H de Rivera, SD Sheridan, RH Perlis, S. McCarroll, B. Stevens, A Subramanian, R Nehme, L. Rubin
Stem Cell Reports X chromosome factor Kdm6a enhances cognition independent of its demethylase function in the aging XY male brain
CK Shaw, S Abdulai-Saiku, F Marino, D Wang, EJ Davis, B Panning, D. Dubal
J Gerontol A Biol Sci Med Sci Lack of accelerated ovarian aging in a follicle-stimulating hormone receptor haploinsufficiency mode
K Mehalko, M Kim, S Paye, K Koh, RJ Lu, B. Benayoun
Transl Med Aging