Plasticity and the Aging Brain

The Simons Collaboration on Plasticity and the Aging Brain aims to discover mechanisms of resilience and maintenance in the aging brain and to establish a baseline for age-related changes in plasticity across many model systems, in order to identify potential interventions to minimize cognitive decline and extend healthy lifespan.

Events & Lectures

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  • April 1 - 15, 2022

    Georgia Institute of Technology
    Related Cognitive Aging Conference

    The biennial Cognitive Aging Conference is the premier conference for presentation of research about aging and cognition based on experimental cognitive psychology, cognitive neuroscience of aging, human factors and ergonomics, and longitudinal studies of age-related cognitive change, its correlates, and determinants.

    The next Cognitive Aging Conference will be held in Atlanta, Georgia in Spring 2022. See the Conference Description page for more information.

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  • July 14 - 17, 2022

    University of Wisconsin–Madison
    Related Metabolism, Aging, Pathogenesis, and Stress in C. elegans

    The 2022 C. elegans “Topics” Meeting “Metabolism, Aging, Pathogenesis, and Stress” (MAPS 2022), on campus at the University of Wisconsin-Madison, Memorial Union will host researchers studying fundamental questions regarding increasing health-span and reducing aging-associated decline.

    Due to the continued uncertainty caused by COVID-19 we regret that we have decided to cancel the 2020 meeting. We look forward to being able to host the meeting July 14 – 17, 2022 in Madison, Wisconsin, SAVE THE DATE!

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  • September 27 - October 1, 2022

    Cold Spring Harbor Laboratory
    Related Mechanisms of Aging

    The meeting will explore the regulation and function of genes and processes that are now known or suspected to control cellular and/or organismic aging. Abstract Deadline: July 8, 2022

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  • July 4 - 9, 2023

    Barcelona, Spain
    Related Gordon Conference Biology of Aging

    While the biology of aging is still a relatively new field, this GRC has become the premier forum for unpublished data presentation and discussions, resulting in a meeting where one can view exciting current science and also see the future directions of the field. Applications for this meeting must be submitted by June 6, 2021.

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Research Highlights

Exercise plasma boosts memory and dampens brain inflammation via clusterin

Z De Miguel, N Khoury, MJ Betley, B Lehallier, D Willoughby, N Olsson, AC Yang, O Hahn, N Lu, RT Vest, LN Bonanno, L Yerra, L Zhang, NL Saw, JK Fairchild, D Lee, H Zhang, PL McAlpine, K Contrepois, M Shamloo, JE Elias, TA Rando, T. Wyss-Coray

Physical exercise is generally beneficial to all aspects of human and animal health, slowing cognitive ageing and neurodegeneration1. The cognitive…



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