Computational Biology: Publications
Read the latest papers published by our research teams.
Results
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CryoBench: Diverse and challenging datasets for the heterogeneity problem in cryo-EM
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Unraveling the Molecular Complexity of N-Terminus Huntingtin Oligomers: Insights into Polymorphic Structures
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Computational tools for cellular scale biophysics
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Dynamical arrest in active nematic turbulence
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Cytoplasmic stirring by active carpets
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E. coli do not count single molecules
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Yardangs sculpted by erosion of heterogeneous material
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Good Rates From Bad Coordinates: The Exponential Average Time-dependent Rate Approach
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DIPG-15. NOVEL CNS SENSING SYNNOTCH-CAR T CELLS FOR TARGETING DIFFUSE MIDLINE GLIOMA
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Measuring and modeling the dynamics of mitotic error correction
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Variational bounds and nonlinear stability of an active nematic suspension
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Martini without the twist: Unveiling a mechanically correct microtubule through bottom-up coarse-graining in Martini 3
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MousiPLIER: A Mouse Pathway-Level Information Extractor Model
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Temperature compensation through kinetic regulation in biochemical oscillators
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Molecular adaptations in response to exercise training are associated with tissue-specific transcriptomic and epigenomic signatures
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Learning fast, accurate, and stable closures of a kinetic theory of an active fluid
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Microstructure-Based Modeling of Primary Cilia Mechanics
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Multiscale simulations of molecular recognition by phase separated MUT-16: A scaffolding protein of Mutator foci
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Design of Coiled-Coil Protein Nanostructures for Therapeutics and Drug Delivery
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Deep Learning Sequence Models for Transcriptional Regulation
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BlastAssist: a deep learning pipeline to measure interpretable features of human embryos
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Promoter and Gene-Body RNA-Polymerase II co-exist in partial demixed condensates
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Supercharged coiled-coil protein with N-terminal decahistidine tag boosts siRNA complexation and delivery efficiency of a lipoproteoplex
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ERK inhibits Cic repressor function via multisite phosphorylation
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Combining machine learning with structure-based protein design to predict and engineer post-translational modifications of proteins
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Ensemble Detection of DNA Engineering Signatures
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Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project
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Computational Design of Phosphotriesterase Improves V-Agent Degradation Efficiency
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Specificity, synergy, and mechanisms of splice-modifying drugs
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Training self-learning circuits for power-efficient solutions
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Tapioca: a platform for predicting de novo protein–protein interactions in dynamic contexts
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To be or not to be: orb, the fusome and oocyte specification in Drosophila
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Molecular Signatures of Glomerular Neovascularization in a Patient with Diabetic Kidney Disease
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Peak-agnostic high-resolution cis-regulatory circuitry mapping using single cell multiome data
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Self-organized intracellular twisters
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Protein dynamics underlying allosteric regulation
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The chromatin landscape of healthy and injured cell types in the human kidney
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Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak–Keller–Segel chemotaxis model
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Modulation of Aβ 16–22 aggregation by glucose
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Non-genetic adaptation by collective migration
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Laser ablation and fluid flows reveal the mechanism behind spindle and centrosome positioning
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A high-order fast direct solver for surface PDEs
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Influence of surface viscosities on the electrodeformation of a prolate viscous drop
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Prebifurcation enhancement of imbibition-drainage hysteresis cycles
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Interpretable neural architecture search and transfer learning for understanding CRISPR–Cas9 off-target enzymatic reactions
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Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury
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Soft matter roadmap
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Building a "trap model" of glassy dynamics from a local structural predictor of rearrangements