Computational Biology: Publications
Read the latest papers published by our research teams.
Results
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Modeling and Design of Peptidomimetics to Modulate Protein–Protein Interactions
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Computing structure-based lipid accessibility of membrane proteins with mp_lipid_acc in RosettaMP
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Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation
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Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling
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Explicit Modeling of RNA Stability Improves Large-Scale Inference of Transcription Regulation
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An Adaptive Geometric Search Algorithm for Macromolecular Scaffold Selection
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c-Maf-dependent regulatory T cells mediate immunological tolerance to intestinal microbiota
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Fused regression for multi-source gene regulatory network inference
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Rotamer libraries for the high-resolution design of beta-amino acid foldamers
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Accurate de novo design of hyperstable constrained peptides
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EGRINs (Environmental Gene Regulatory Influence Networks) in rice that function in the response to water deficit, high temperature, and agricultural environments
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An expanded evaluation of protein function prediction methods shows an improvement in accuracy
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PPII Helical Peptidomimetics Templated by Cation–π Interactions
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Side-Chain Conformational Preferences Govern Protein–Protein Interactions
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Integrative neuromechanics of crawling in D. melanogaster larvae
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Racemization barriers of atropisomeric 3,3′-bipyrroles: an experimental study with theoretical verification
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A damage-independent role for 53BP1 that impacts break order and Igh architecture during class switch recombination
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DDX5 and its associated lncRNA Rmrp modulate Th17 cell effector functions
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Active and inactive enhancers cooperate to exert localized and long-range control of gene regulation
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Generalized Stability Approach for Regularized Graphical Models
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Helminth infection promotes colonization resistance via type 2 immunity
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Neocortex: a lean mean storage machine
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Derivation of Neural Circuits from the Similarity Matching Principle
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Big Data, Social Media, and Protest
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Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination
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Do retinal ganglion cells project natural scenes to their principal subspace and whiten them?
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Self-calibrating neural networks for dimensionality reduction
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Environmental gene regulatory influence networks in rice (Oryza sativa): response to water deficit, high temperature and agricultural environments
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4C-ker: a method to reproducibly identify genome-wide interactions captured by 4C-Seq experiments
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Tweeting identity? Ukrainian, Russian, and# Euromaidan
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Robust classification of protein variation using structural modelling and large-scale data integration
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A Miniature Protein Stabilized by a Cation− π Interaction Network
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Text Classification for Automatic Detection of E-Cigarette Use and Use for Smoking Cessation from Twitter: A Feasibility Pilot
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Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet
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Bacillus subtilis Systems Biology: Applications of -Omics Techniques to the Study of Endospore Formation
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Biophysically Motivated Regulatory Network Inference: Progress and Prospects
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Breaking TADs: insights into hierarchical genome organization
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Acute off-target effects of neural circuit manipulations
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A Normative Theory of Adaptive Dimensionality Reduction in Neural Networks
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To Myelinate or Not to Myelinate?
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The Critical Periphery in the Growth of Social Protests
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Toward rational thermostabilization of Aspergillus oryzae cutinase: Insights into catalytic and structural stability
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Multiple abiotic stimuli are integrated in the regulation of rice gene expression under field conditions
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An experimentally supported model of the Bacillus subtilis global transcriptional regulatory network
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Positive-Unlabeled Learning in the Face of Labeling Bias
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Synaptic circuits and their variations within different columns in the visual system of Drosophila
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An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses
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Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms