Eligibility

What research fields are eligible to be supported by this program?

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program.

What institutions are members of the Empire AI consortium and eligible for funding?

Empire AI consortium member institutions eligible for funding are Columbia University, Cornell University, City University of New York (CUNY), State University of New York (SUNY), Rensselaer Polytechnic Institute, New York University, University of Rochester, Rochester Institute of Technology and Icahn School of Medicine at Mount Sinai. Employees of the Flatiron Institute can participate as unfunded collaborators.

Can non-U.S. institutions apply for this award?

The main applicant PI must be from an institution within the Empire AI consortium eligible to receive funding. Additional PIs on a proposal can be employed by institutions outside of the Empire AI consortium, including non-U.S. institutions. Please see our policies regarding non-U.S. Awards.

Funding

What is the maximum allowable budget for the award?

There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Are indirect costs allowed?

Indirect costs are allowed for this award and must follow our indirect cost policy (see our policies). The indirect cost rate is nonnegotiable.

If applications have multiple PIs from different institutions, how will they receive funding?

Applications with multiple PIs from different institutions will be paid directly by the main institution. The additional PI must be added to the “Project Personnel” section to generate a subcontract budget for each PI.

Submission

Frequently asked questions and instructional videos for navigating SAM

For assistance navigating SAM, please refer to the SAM frequently asked questions and instructional videos webpage.

Are deadline times adjusted for time zones?

No. Please be advised that all deadlines are in U.S. Eastern time. We recommend registering early and submitting with ample time for corrections prior to the deadline hour. Site traffic can slow page-load times. You will not be able to submit after the deadline has passed.

Can I make changes to the application once it has been submitted?

If changes are required to the application after submission, you must first contact [email protected]. Applications can only be changed prior to the deadline. Once revised, the application must be sent for sign-off and signed by the Signing Official again in order to resubmit.

The system says my record is locked and won’t let me edit it. What should I do?

Only one person can edit a record at a time. A record will be locked for editing if another user already has it opened, and a gray bar will display at the bottom of the record to prevent multiple users from overwriting one another’s changes. Ask other users at your institution to close the application, then refresh your page. If this still does not correct the issue, please reach out to [email protected].

Note regarding potential referral of an application to The Simons Foundation International, Ltd. (SFI)

Please note that in the event of budgetary or other considerations, The Simons Foundation, Inc. (“the Foundation” or “SF”) reserves the right to refer an application to SFI for consideration and funding. SFI and SF have entered into an agreement pursuant to which SF provides program operations and grant administration services, including payment processing, to SFI. SFI grant recipients are subject to SF Policies and Procedures.

How do I submit my application?

All applications must be submitted via the Simons Award Manager (SAM). Please refer to the submission instructions for detailed steps on how to complete and submit your application. You will not be able to submit if the deadline has passed. We will not accept applications or individual application materials submitted via email or ma

Can I make changes to the application once it has been sent for sign-off?

If changes are required to the application after it has been sent for sign-off, the Signing Official must send the application back for revisions. Once revised, the application must be sent for sign-off again and signed by the Signing Official in order to submit by the deadline. You will not be able to submit once the deadline has passed.

More Funding Opportunities

The MPS division invites applications for the Scientific Software Research Faculty Award, which supports new research professor positions in existing academic departments to be filled by scientific software-focused researchers no later than September 1, 2027.

Apply by January 21, 2027

The Fellows-to-Faculty Award program supports talented early career scientists by facilitating their transition into tenure-track faculty positions. The focus of this program is the $600,000 USD three (3) year faculty research grant.

Apply by January 13, 2027

Supports junior HBCU faculty with protected research time to advance their work, pursue grants and publications, build collaborations, and create pathways for students into graduate STEM programs.

Apply by November 12, 2026