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Bringing people and ideas together to fund, conduct, and share transformative science.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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  1. Prefrontal Corticotectal Neurons Enhance Visual Processing through the Superior Colliculus and Pulvinar Thalamus.

    Neuron, October 15, 2019

    F Hu, T Kamigaki, Z Zhang, S Zhang, U Dan, and Y Dan

  2. Compound stimuli reveal the structure of visual motion selectivity in macaque MT neurons.

    eNeuro., October 11, 2019

    AD Zaharia, RLT Goris, J. Anthony Movshon, and Eero P. Simoncelli

  3. A computational account of threat-related attentional bias.

    PLoS Comput Biol., October 10, 2019

    T Wise, J Michely, Peter Dayan, and RJ Dolan

  4. Designing and Interpreting Psychophysical Investigations of Cognition.

    Neuron, October 9, 2019

    ML Waskom, G Okazawa, and Roozbeh Kiani

  5. Population imaging of neural activity in awake behaving mice.

    Nature, October 9, 2019

    KD Piatkevich, S Bensussen, HA Tseng, SN Shroff, VG Lopez-Huerta, D Park, et al.

  6. Computational Neuroethology: A Call to Action.

    Neuron, October 9, 2019

    Sandeep Robert Datta, David J. Anderson, K Branson, Pietro Perona, and Andrew Leifer

  7. Motor cortex signals for each arm are mixed across hemispheres and neurons yet partitioned within the population response

    eLife, October 9, 2019

    Katherine Cora Ames and Mark M. Churchland

  8. Depth-resolved fiber photometry with a single tapered optical fiber implant.

    Nat Methods., October 7, 2019

    F Pisano, M Pisanello, SJ Lee, J Lee, E Maglie, A Balena, et al.

  9. Internal models of sensorimotor integration regulate cortical dynamics

    Nature Neuroscience, October 7, 2019

    Seth W. Egger, Evan D. Remington, Chia-Jung Chang, and Mehrdad Jazayeri

  10. Chronic Implantation of Multiple Flexible Polymer Electrode Arrays.

    J Vis Exp., October 4, 2019

    JE Chung, HR Joo, CN Smyth, JL Fan, C Geaghan-Breiner, H Liang, et al.

  11. Visual novelty, curiosity, and intrinsic reward in machine learning and the brain

    Current Opinion in Neurobiology, October 1, 2019

    Andrew Jaegle, Vahid Mehrpour, and Nicole Rust

  12. Harnessing behavioral diversity to understand neural computations for cognition

    Current Opinion in Neurobiology, October 1, 2019

    Simon Musall, Anne E. Urai, David Sussillo, and Anne K. Churchland

  13. Real-time volumetric microscopy of in vivo dynamics and large-scale samples with SCAPE 2.0.

    Nat Methods., October 1, 2019

    V Voleti, KB Patel, W Li, C Perez Campos, S Bharadwaj, H Yu, et al.

  14. Single-trial neural dynamics are dominated by richly varied movements.

    Nat Neurosci., October 1, 2019

    S Musall, MT Kaufman, AL Juavinett, S Gluf, and Anne K. Churchland

  15. Believing in dopamine

    Nature Reviews Neuroscience, September 30, 2019

    Samuel J. Gershman and Naoshige Uchida

  16. Reconfiguring motor circuits for a joint manual and BCI task.

    IEEE Trans Neural Syst Rehabil Eng., September 27, 2019

    B Lansdell, I Milovanovic, C Mellema, EE Fetz, Adrienne Fairhall, and CT Moritz

  17. The role of adaptation in neural coding.

    Curr Opin Neurobiol., September 27, 2019

    Al Weber and Adrienne Fairhall

  18. Single-Cell Reconstruction of Emerging Population Activity in an Entire Developing Circuit

    Cell, September 26, 2019

    Yinan Wan, Ziqiang Wei, Loren L. Looger, Minoru Koyama, Shaul Druckmann, and Philipp J.Keller

  19. Task-Dependent Changes in the Large-Scale Dynamics and Necessity of Cortical Regions

    Neuron, September 26, 2019

    Lucas Pinto, Kanaka Rajan, Brian DePasquale, Stephan Y. Thiberge, David W. Tank, and Carlos Brody

  20. Altered functional interactions between neurons in primary visual cortex of macaque monkeys with experimental amblyopia.

    J Neurophysiol., September 25, 2019

    K Acar, L Kiorpes, J. Anthony Movshon, and MA Smith

  21. Engineering a Less Artificial Intelligence.

    Neuron., September 25, 2019

    FH Sinz, Xaq Pitkow, J Reimer, M Bethge, and AS Tolias

  22. Abstract goal representation in visual search by neurons in the human pre-supplementary motor area.

    Brain., September 24, 2019

    S Wang, AN Mamelak, Ralph Adolphs, and U Rutishauser

  23. Neural Correlates of Optimal Multisensory Decision Making under Time-Varying Reliabilities with an Invariant Linear Probabilistic Population Code.

    Neuron, September 23, 2019

    H Hou, Q Zheng, Y Zhao, Alexandre Pouget, and Y Gu

  24. Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain.

    Cell, September 19, 2019

    J Winnubst, E Bas, TA Ferreira, Z Wu, MN Economo, P Edson, et al.

  25. Responses of neurons in macaque MT to unikinetic plaids.

    J Neurophysiol., September 11, 2019

    P Wallisch and J. Anthony Movshon

  26. Control of Non-REM Sleep by Midbrain Neurotensinergic Neurons.

    Neuron., September 6, 2019

    P Zhong, P Zhang, Z Barger, C Ma, D Liu, X Ding, et al.

  27. A canonical computational model of cortical area V2

    Journal of Vision, September 3, 2019

    Timothy D Oleskiw and Eero P. Simoncelli

  28. Simultaneous multi-area recordings suggest that attention improves performance by reshaping stimulus representations

    Nature Neuroscience, September 2, 2019

    Douglas A. Ruff and Marlene Cohen

  29. Population response magnitude variation in inferotemporal cortex predicts image memorability

    eLife, August 29, 2019

    Andrew Jaegle, Vahid Mehrpour, Yalda Mohsenzadeh, Travis Meyer, Aude Oliva, and Nicole Rust

  30. The striatum specifies the statistics of behavior.

    Neuropsychopharmacology, August 29, 2019

    JE Markowitz and Sandeep Robert Datta

  31. Recruitment of GABAergic Interneurons in the Barrel Cortex during Active Tactile Behavior

    Neuron, August 26, 2019

    Jianing Yu, Hang Hu, Ariel Agmon, and Karel Svoboda

  32. A point-process matched filter for event detection and decoding from population spike trains.

    J Neural Eng., August 22, 2019

    N Sadras, Bijan Pesaran, and MM Shanechi

  33. A critique of pure learning and what artificial neural networks can learn from animal brains

    Nature Communications, August 21, 2019

    Anthony Zador

  34. A Data-Compressive Wired-OR Readout for Massively Parallel Neural Recording.

    IEEE Trans Biomed Circuits Syst., August 15, 2019

    D Muratore, P Tandon, M Wootters, E. J. Chichilnisky, S Mitra, and B Murmann

  35. Backtracking during navigation is correlated with enhanced anterior cingulate activity and suppression of alpha oscillations and the 'default-mode' network.

    Proc Biol Sci., August 14, 2019

    AH Javadi, EZ Patai, E Marin-Garcia, A Margois, HM Tan, D Kumaran, et al.

  36. Chronically-implanted Neuropixels probes enable high yield recordings in freely moving mice.

    Elife., August 14, 2019

    AL Juavinett, G Bekheet, and Anne K. Churchland

  37. Recruitment of GABAergic Interneurons in the Barrel Cortex during Active Tactile Behavior.

    Neuron, August 13, 2019

    J Yu, H Hu, A Agmon, and Karel Svoboda

  38. The intrinsic attractor manifold and population dynamics of a canonical cognitive circuit across waking and sleep

    Nature Neuroscience, August 12, 2019

    Rishidev Chaudhuri, Berk Gerçek, Biraj Pandey, Adrien Peyrache, and Ila Fiete

  39. Training dynamically balanced excitatory-inhibitory networks.

    PLoS One., August 8, 2019

    A Ingrosso and Larry Abbott

  40. Transplanted cells are essential for the induction but not the expression of cortical plasticity.

    J Neurosci., August 7, 2019

    MS Hoseini, B Rakela, Q Flores-Ramirez, AR Hasenstaub, A Alvarez-Buylla, and Michael Stryker

  41. Optimal policy for multi-alternative decisions.

    Nat Neurosci., August 5, 2019

    S Tajima, J Drugowitsch, N Patel, and Alexandre Pouget

  42. Kilohertz frame-rate two-photon tomography.

    Nat Methods., August 1, 2019

    A Kazemipour, O Novak, D Flickinger, JS Marvin, AS Abdelfattah, J King, et al.

  43. Viewpoints: Approaches to defining and investigating fear.

    Nat Neurosci., August 1, 2019

    D Mobbs, Ralph Adolphs, MS Fanselow, LF Barrett, JE LeDoux, K Ressler, et al.

  44. Monitoring Behaviorally Induced Biochemical Changes Using Fluorescence Lifetime Photometry

    Frontiers in Neuroscience, July 31, 2019

    Suk Joon Lee, Yao Chen, Bart Lodder, and Bernardo Sabatini

  45. Convergent Temperature Representations in Artificial and Biological Neural Networks

    Neuron, July 31, 2019

    Martin Haesemeyer, Alexander F. Schier, and Florian Engert

  46. Error-correcting dynamics in visual working memory

    Nature Communications, July 29, 2019

    Matthew F. Panichello, Brian DePasquale, Jonathan Pillow, and Timothy J. Buschman

  47. Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets

    Nature Neuroscience, July 29, 2019

    Caroline L. Wee, Maxim Nikitchenko, Wei-Chun Wang, Sasha J. Luks-Morgan, Erin Song, James A. Gagnon, et al.

  48. Correlation transfer by layer 5 cortical neurons under recreated synaptic inputs in vitro.

    J Neurosci., July 25, 2019

    D Linaro, GK Ocker, Brent Doiron, and M Giugliano

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