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November 19, 2014
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PublicationBrain function relies on the coordination of activity across multiple, recurrently connected brain areas. For instance, sensory information encoded in early sensory areas is relayed to, and further …
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PublicationA recent formulation of predictive coding theory proposes that a subset of neurons in each cortical area encodes sensory prediction errors, the difference between predictions relayed from higher …
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PublicationThe brain is composed of many functionally distinct areas. This organization supports distributed processing, and requires the coordination of signals across areas. Our understanding of how populations of …
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PublicationOptogenetics has revolutionized neuroscience in small laboratory animals, but its effect on animal models more closely related to humans, such as non-human primates (NHPs), has been mixed …
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PublicationThe neural basis of perceptual decision making has typically been studied using measurements of single neuron activity, though decisions are likely based on the activity of large neuronal …
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PublicationNearly all brain functions involve routing neural activity among a distributed network of areas. Understanding this routing requires more than a description of interareal anatomical connectivity: it requires …
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PublicationCrowding is a profound loss of discriminability of visual features, when a target stimulus is surrounded by distractors. Numerous studies of human perception have characterized how crowding depends …
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PublicationSensory signals give rise to patterns of neural activity, which the brain uses to infer properties of the environment. For the visual system, considerable work has focused on …
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Publication… relate fluctuations in small neuronal population responses, recorded simultaneously in primary visual cortex (V1) and area V4 of awake monkeys, to perceptual reports in an orientation discrimination …
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PublicationMost brain functions involve interactions among multiple, distinct areas or nuclei. For instance, visual processing in primates requires the appropriate relaying of signals across many distinct cortical areas …
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Publication… aspects of cortical computation. Specifically, we show that cross-orientation masking, a form of normalization, can be strengthened or weakened by adaptation depending on the temporal contingencies …
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PublicationPrimate motor cortex projects to spinal interneurons and motoneurons, suggesting that motor cortex activity may be dominated by muscle-like commands. Observations during reaching lend support to this …
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PublicationDimensionality reduction has been applied in various brain areas to study the activity of populations of neurons. To interpret the outputs of dimensionality reduction, it is important to …
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PublicationShared neural variability is ubiquitous in cortical populations. While this variability is presumed to arise from overlapping synaptic input, its precise relationship to local circuit architecture remains unclear …