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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Topology and Complexity

November 19, 2014

Results

  1. 2025 Autism Rat Consortium Meeting Held in New York City

    January 13, 2026
    On September 29, 2025, the SFARI Autism Rat Consortium (ARC) held its annual meeting in the Usher Institute of the University of Edinburgh. This year’s event brought …
  2. Watch: SCGB Scientists Reflect on 11 Years of Progress in Systems Neuroscience

    May 29, 2025
    In these videos, leading neuroscientists share discoveries, memories and lessons from their international collaboration to map the neural processes behind cognition.
  3. How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers

    February 20, 2025
    The collaboration of 19 laboratories and dozens of neuroscientists has collected data that could reveal how regions throughout the brain behave during the decision-making process.
  4. 5 Simons-Supported Investigators Receive Awards From National Academy of Sciences

    January 27, 2025
    … Origins of Life (SCOL) Sutherland will receive the NAS Award in Early Earth and Life Studies — Stanley Miller Medal for advancing our understanding of the chemical origins …
  5. Crossing the Divide: Defining Neurons by Both Genes and Function

    November 22, 2022
    With better tools for exploring the many facets of neurons, neuroscientists are building a more detailed glossary of cell types in the mammalian brain.
  6. In Mapping Mistakes, a Window to the Inner Mind

    May 26, 2022
    New efforts explore how internal states influence decision-making.
  7. How Decision-Making Changes With Age

    March 2, 2022
    Building on decades of research on the neural circuitry of decision-making, researchers are now exploring how those circuits evolve over the life span.
  8. Building a New Model for Neuroscience Research

    January 26, 2022
    Four years into its run, the International Brain Lab, a collaboration among 22 labs, is demonstrating a novel approach to team-based neuroscience.
  9. Bridge to Independence Fellows Meeting Highlights Research Findings and Plans of the Next Generation of SFARI Autism Scientists

    January 30, 2020
    On May 21, 2019, the recipients of the SFARI Bridge to Independence Award gathered at the Simons Foundation to discuss their scientific findings and plans in autism research.
  10. Thinking on the Go: Why Does the Whole Brain Light Up for Just the Smallest Movements?

    November 26, 2019
    Seemingly meaningless movements — even a quick twitch of a limb — produce abundant, widespread and high-dimensional activity in the cortex. How might the brain use this information?
  11. Why Neurophysiology Needs an MP3

    October 2, 2019
    When it comes to data sharing, neuroscience lags behind many other fields. But a growing number of large-scale projects are inspiring new efforts to develop workable tools.
  12. How Natural Should Laboratory Behavior Be?

    February 13, 2018
    A bird can respond to a tone, but is that the same as responding to a birdcall? Anne Churchland and collaborators propose a framework for evaluating behavioral tasks …
  13. Virtual Brain Lab Brings Together Leading Neuroscientists Across the World

    September 19, 2017
    … project, its emphasis on data sharing and a focus on a single behaviour will help to move the field of neuroscience forward by illustrating how many labs …
  14. Theoretical Brain Studies Highlighted in Special Issue of Nature Neuroscience

    February 24, 2016
    SCGB investigators take center stage and discuss current thinking on a range of topics, including neural circuitry and theoretical principles of memory

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