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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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  • Newsletter Sign Up
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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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  • Presidential Lectures
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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Watch: SCGB Scientists Reflect on 11 Years of Progress in Systems Neuroscience

    May 29, 2025
    In these videos, leading neuroscientists share discoveries, memories and lessons from their international collaboration to map the neural processes behind cognition.
  2. Searching for Shapes in Neural Activity

    April 28, 2022
    Massive neural recordings combined with advanced analyses can distill insight from enigmatic data. How far can these tools take us?
  3. Scoring the Brain: How Benchmark Datasets and Other Tools Are Solving Key Challenges in Neuroscience

    August 25, 2021
    With standardized datasets, community-building challenges and simplified software bundles, research initiatives strive to bring uniformity to analysis in neuroscience.
  4. Practicing Neuroscience During a Pandemic

    April 20, 2020
    In the wake of massive lab shutdowns, systems and computational neuroscientists are figuring out how to continue their work without performing experiments.
  5. Neural Coding: A Truly Cerebral Puzzle

    April 9, 2020
    Individual neurons and regions of the brain can encode surprisingly strange combinations of information.
  6. Beauty and the Brain

    February 5, 2020
    Cerebral fascinations: We asked our neuroscientists why they find the brain beautiful.
  7. Uncovering Hidden Dimensions in Brain Signals

    November 11, 2019
    New nonlinear methods for analyzing high-dimensional neural activity can better characterize the most important patterns in the data.
  8. How BrainCogs Learned to Share: A Case Study

    October 4, 2019
    Members of the multi-lab BrainCogs collaboration are using DataJoint to more easily access each other’s data.
  9. How the Brain Uses Neural Sequences in Navigation, Memory and Beyond

    January 28, 2019
    SCGB director David Tank discusses how virtual reality and two-photon imaging can probe the role of neural sequences in cognition.
  10. Virtual Brain Lab Brings Together Leading Neuroscientists Across the World

    September 19, 2017
    … project, its emphasis on data sharing and a focus on a single behaviour will help to move the field of neuroscience forward by illustrating how many labs …

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