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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
  • Research News
  • Funding Announcements
  • Newsletter Sign Up
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  • Media Relations

We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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  • Presidential Lectures
  • Presents
  • Flatiron Events
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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Topology and Complexity

November 19, 2014

Results

  1. Biological Brains Inspire a New Building Block for Artificial Neural Networks

    January 26, 2026
    While artificial intelligence systems have advanced tremendously in recent years, they still lag behind the performance of real brains in reliability and efficiency. A new type of computational …
  2. New Computational Model of Real Neurons Could Lead to Better AI

    June 24, 2024
    The new model developed by researchers at the Flatiron Institute proposes that biological neurons have more control over their surroundings than previously thought, something that could be replicated …
  3. Researchers Create First-Ever Map of a Single Animal’s Early Visual System

    September 28, 2023
    A team of scientists at the Flatiron Institute and their colleagues have mapped out the entire early visual system — from eyes to neurons — for a tiny parasitic wasp …
  4. Computational Model Uncovers New Insights Into How Our Brains Store Information

    March 9, 2023
    With the new model, researchers reveal how memories and learned behaviors can remain strong, even in the face of shifting neural representations.
  5. Watch: Building the Ultimate Brain Map

    March 29, 2022
    In efforts to construct a map of neural connections in the brain, researchers at the Flatiron Institute’s Center for Computational Neuroscience are turning to an unlikely source …
  6. Computation Opens New Doors for Science

    March 4, 2021
    At the Flatiron Institute, researchers across domains have access to powerful processors and a team of computing specialists.
  7. Beauty and the Brain

    February 5, 2020
    Cerebral fascinations: We asked our neuroscientists why they find the brain beautiful.
  8. Open-Source Software Tracks Neural Activity in Real Time

    February 28, 2019
    The tool, called CaImAn, replaces the process of manually tracking the location and activity of neurons.

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