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  1. Neurophotonic tools for microscopic measurements and manipulation: status report

    Publication
    Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative focused on development of technologies for advancement of neuroscience. For the last seven years, Neurophotonics …

  2. 3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images

    Publication
    Despite recent improvements in microscope technologies, segmenting and tracking cells in three-dimensional time-lapse images (3D + T images) to extract their dynamic positions and activities remains a …

  3. Localized semi-nonnegative matrix factorization (LocaNMF) of widefield calcium imaging data.

    Publication
    Widefield calcium imaging enables recording of large-scale neural activity across the mouse dorsal cortex. In order to examine the relationship of these neural signals to the resulting …

  4. Widespread receptor-driven modulation in peripheral olfactory coding.

    Publication
    Olfactory responses to single odors have been well characterized but in reality we are continually presented with complex mixtures of odors. We performed high-throughput analysis of single …

  5. Real-time volumetric microscopy of in vivo dynamics and large-scale samples with SCAPE 2.0.

    Publication
    The limited per-pixel bandwidth of most microscopy methods requires compromises between field of view, sampling density and imaging speed. This limitation constrains studies involving complex motion or …

  6. Light-Sheet Microscopy in Neuroscience.

    Publication
    Light-sheet microscopy is an imaging approach that offers unique advantages for a diverse range of neuroscience applications. Unlike point-scanning techniques such as confocal and two-photon …

  7. Characterization of Proprioceptive System Dynamics in Behaving Drosophila Larvae Using High-Speed Volumetric Microscopy.

    Publication
    Proprioceptors provide feedback about body position that is essential for coordinated movement. Proprioceptive sensing of the position of rigid joints has been described in detail in several systems …

  8. High-speed 3D imaging of cellular activity in the brain using axially-extended beams and light sheets.

    Publication
    As optical reporters and modulators of cellular activity have become increasingly sophisticated, the amount that can be learned about the brain via high-speed cellular imaging has increased …