Search

What are you looking for?

  1. Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation

    Publication
    The segregation of the epiblast (EPI) and primitive endoderm (PE) cell types in the preimplantation mouse embryo is not only a crucial decision that sets aside the precursors …

  2. Generation of fate patterns via intercellular forces

    Publication
    Studies of fate patterning during development typically emphasize cell-cell communication via diffusible chemical signals. Recent experiments on stem cell colonies, however, suggest that in some cases mechanical …

  3. Nuclear instance segmentation and tracking for preimplantation mouse embryos

    Publication
    For investigations into fate specification and morphogenesis in time-lapse images of preimplantation embryos, automated 3D instance segmentation and tracking of nuclei are invaluable. Low signal-to-noise …

  4. A model of replicating coupled oscillators generates naturally occurring cell networks

    Publication
    When a founder cell and its progeny divide with incomplete cytokinesis, a network forms in which each intercellular bridge corresponds to a past mitotic event. Such networks are …

  5. Quantitative models for building and growing fated small cell networks

    Publication
    Small cell clusters exhibit numerous phenomena typically associated with complex systems, such as division of labour and programmed cell death. A conserved class of such clusters occurs during …