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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. INSYNC-AS Inaugural Meeting Discusses the Therapeutic Landscape for Angelman Syndrome

    April 19, 2022
    A joint project of the Foundation for Angelman Syndrome Therapeutics (FAST) and SFARI, the International Angelman Syndrome Research Council (INSYNC-AS) held its inaugural meeting on July 9 …
  2. SFARI Hosts Workshop on Newborn Screening

    February 28, 2022
    On September 27, 2021, SFARI convened a one-day virtual workshop to explore and discuss opportunities and risks for early detection of neurodevelopmental disorders through genomic sequencing.
  3. SFARI Workshop Discusses Opportunities To Study Maternal Infection and Autism Risk During COVID-19 Pandemic

    December 11, 2020
    On July 29, 2020, SFARI convened an online workshop to explore environmental (maternal and fetal) risk factors for autism spectrum disorder in the context of COVID-19 infection.
  4. Transition in SFARI Directorship: Update

    October 7, 2020
    Louis Reichardt, who has served as director of SFARI since 2013, finished his tenure here on September 28. John Spiro has been appointed interim director of SFARI until …
  5. SFARI Workshop Explores Challenges and Opportunities of Gene Therapies for Autism Spectrum Disorder

    June 24, 2020
    On February 6–7, 2020, SFARI convened a two-day workshop to explore the possibility of gene therapies for autism spectrum disorder.
  6. Can Autism Therapy Be Tailored?

    May 29, 2020
    Leveraging personalized genomics can aid the development of effective autism therapies, promising new research suggests.
  7. Simons Searchlight: Rebranding and Expanding the Program

    November 4, 2019
    In this blog post, Wendy Chung and John Spiro outline some of the important ways in which the Simons Searchlight program has been recently expanded, including increasing the …
  8. SFARI 2017 Pilot and Research Awardees Announced

    October 30, 2017
    SFARI is pleased to announce that it has awarded 32 grants (19 Pilot Awards and 13 Research Awards) in response to the 2017 Pilot and Research Awards request …
  9. SFARI supports preprints for the life sciences

    May 20, 2016
    SFARI’s deputy scientific director, John Spiro, outlines two important changes that have been implemented in light of SFARI’s support for preprints of life science research findings …
  10. SFARI’s funding priorities for the upcoming year

    August 12, 2014
    On 2 September, we plan to announce a new request for applications. Letters of intent, the short statements that precede full applications, are due no later than 10 …
  11. SFARI’s priorities, funding decisions for 2014 grants cycle

    September 3, 2013
    Today, we’re announcing a new request for applications. Letters of intent, the short statements that precede full applications, are due no later than 11 October. It seems …
  12. Challenging choices: How we make funding decisions

    October 30, 2012
    Which grant applications should SFARI choose to fund each year? The principles that guide that decision are nuanced and evolve as new results emerge. But there are some …
  13. Difficult decisions: An inside look at SFARI’s grant-making

    April 11, 2011
    In November, the Simons Foundation Autism Research Initiative (SFARI) launched a request for applications, calling for letters of intent from individuals who will conduct bold, imaginative and rigorous …

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