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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. SFARI Hosts 2026 Investigator Meeting

    June 15, 2026
    The Simons Foundation Autism Research Initiative held its annual investigator meeting on March 16–18, 2026, in New York City.
  2. 2025 Autism Rat Consortium Meeting Held in New York City

    January 13, 2026
    On September 29, 2025, the SFARI Autism Rat Consortium (ARC) held its annual meeting in the Usher Institute of the University of Edinburgh. This year’s event brought …
  3. Cis-Regulation Therapy Rescues SCN2A-Related Neurological Dysfunction

    November 19, 2025
    … Neurosci. 27, 1864–1879 (2024) PubMed Karczewski K.J. et al. Nature 581, 434–443 (2020) PubMed Howe K.L. et al. Ensembl 2021. Nucleic Acids Res …
  4. SFARI Researchers Gather in Edinburgh for 2024 Autism Rat Consortium Meeting

    October 30, 2024
    On September 18, 2024, the SFARI Autism Rat Consortium (ARC) held its annual meeting in the Usher Institute of the University of Edinburgh. This year’s event brought …
  5. 2023 SFARI Cross-Species Studies of ASD Awardees Announced

    January 18, 2024
    SFARI is pleased to announce that it intends to fund three collaborative projects in response to the 2023 Cross-Species Studies of ASD request for applications.
  6. SFARI Autism Rat Models Consortium Awardees Announced

    April 29, 2022
    SFARI is pleased to announce that it intends to fund seven grants in response to the Autism Rat Models Consortium request for applications.
  7. SFARI Fall 2020 Science Meeting Highlights New Developments in Autism Research

    April 28, 2021
    Because of the coronavirus pandemic, SFARI ran the fall 2020 science meeting virtually in a series of six weekly webinars, beginning on October 2, 2020. SFARI investigators presented …
  8. SFARI 2019 Director Awards Announced

    March 19, 2020
    SFARI is pleased to announce that 10 Director Awards were awarded in 2019. These projects include, but are not limited to, studies that aim to enhance existing SFARI …
  9. Seeing Through a Forest of SCN2A Gene Variation

    February 19, 2020
    On August 2–3, 2019, people from around the world met in Seattle, Washington, to review recent findings about mutations to the sodium channel encoded by SCN2A. Organized …
  10. New Findings in Autism Research Presented at the SFARI Spring 2019 Science Meeting

    December 18, 2019
    SFARI held its 15th science meeting April 7–9, 2019. Over 100 SFARI investigators, collaborators and foundation staff convened to discuss recent findings on the genetics, molecular- and …
  11. Unexpected Synaptic Role for the Autism Risk Gene Scn2a

    July 26, 2019
    Kevin Bender, Stephan Sanders and colleagues show that there is an unexpectedly critical role for the autism risk gene Scn2a, which encodes the sodium channel NaV1.2, in …
  12. SFARI Spring 2018 Science Meeting Discussed Latest Developments in Autism Research

    September 7, 2018
    SFARI held its thirteenth science meeting April 8–12, 2018. SFARI investigators, collaborators and foundation staff came together to discuss recent findings in autism genetics, molecular and system …
  13. SFARI 2017 Pilot and Research Awardees Announced

    October 30, 2017
    SFARI is pleased to announce that it has awarded 32 grants (19 Pilot Awards and 13 Research Awards) in response to the 2017 Pilot and Research Awards request …

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