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PublicationAwakening from sleep reflects a profound transformation in neural activity and behavior. The thalamus is a key controller of arousal state, but whether its diverse nuclei exhibit coordinated …
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PublicationBackground: Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is one of the earliest manifestations of α synucleinopathies. Brainstem pathophysiology underlying REM sleep behavior disorder has been …
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PublicationSleep is essential for brain function in a surprisingly diverse set of ways. In the short term, lack of sleep leads to impaired memory and attention; in the …
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Imaging faster neural dynamics with fast fMRI: A need for updated models of the hemodynamic response
PublicationFast fMRI enables the detection of neural dynamics over timescales of hundreds of milliseconds, suggesting it may provide a new avenue for studying subsecond neural processes in the … -
PublicationRecent developments in optical microscopy, applicable for large-scale and longitudinal imaging of cortical activity in behaving animals, open unprecedented opportunities to gain a deeper understanding of neurovascular …
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Publicationuring sleep, the brain experiences large fluctuations in blood volume and altered coupling between neural and vascular signals.
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PublicationDuring sleep, the brain experiences large fluctuations in blood volume and altered coupling between neural and vascular signals.
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PublicationSleep is essential for both cognition and maintenance of healthy brain function. Slow waves in neural activity contribute to memory consolidation, whereas cerebrospinal fluid (CSF) clears metabolic waste …