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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Topology and Complexity

November 19, 2014

Results

  1. A New Era in Neural Recording

    July 19, 2021
    Novel technologies to simultaneously record from hundreds to thousands of neurons over weeks and months grant access to the brain at an unprecedented resolution. Researchers are now tackling …
  2. Geometrical Thinking Offers a Window Into Computation

    April 7, 2021
    In a pair of studies, researchers use a novel way of examining data to explain how animals simultaneously encode tiny details and the big picture.
  3. Discoveries of Rotational Dynamics Add to Puzzle of Neural Computation

    July 14, 2020
    Neuroscientists are uncovering patterns of neuron population activity during different movements and in new places, but why these dynamics exist is still a mystery
  4. A Tale of 2 Brain Regions: Population-Level Analysis Reveals Differences Not Evident in Single Cells

    December 4, 2018
    A new method for analyzing neural dynamics reveals that two regions involved in movement exhibit different patterns of activity, suggesting they perform different computations.
  5. Untangling Neurons

    June 13, 2017
    Networks of neurons in the motor cortex may generate extra dimensions of information in order to create unambiguous motor plans
  6. How Do Different Brain Regions Interact To Enhance Function?

    March 3, 2016
    This question and others have come to the fore as advances in experimental neuroscience bring in data that challenge conventional wisdom
  7. Global Brain Meeting Explores the Puzzle of Cognition

    December 1, 2015
    The inaugural meeting of the Simons Collaboration on the Global Brain reviewed the progress made in understanding the neural basis of memory, decision making and behavior
  8. Thought-Controlled Technology Improves Thanks to Motor Cortex Findings

    September 10, 2015
    A new understanding of how motor neurons fire should lead to a dramatic increase in performance of brain-machine interfaces
  9. 2015 Klingenstein-Simons Fellowship Awards in the Neurosciences Announced

    August 4, 2015
    … Institute of Technology “Neural dynamics supporting the integration of prior knowledge and sensory evidence in cortical circuits” https://mcgovern.mit.edu/principal-investigators/mehrdad-jazayeri http://bcs …

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