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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
  • Research News
  • Funding Announcements
  • Newsletter Sign Up
  • Press Releases
  • Media Relations

We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

  • Events Calendar
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  • Presidential Lectures
  • Presents
  • Flatiron Events
  • Past Events

Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Barriers, motivators and strategies to increase participation in genetic research among Asian and Black families of autistic individuals.

    Publication
  2. Evidence-based recruitment strategies for clinical research: Study personnel's and research participants' perceptions about successful methods of outreach for a U.S. Autism-Research Cohort.

    Publication
  3. Effectiveness of multimodal participant recruitment in SPARK, a large, online longitudinal research study of autism.

    Publication
  4. Use of a Best Practice Alert (BPA) to increase diversity within a U.S.-based autism research cohort.

    Publication
  5. Utilization of a Best Practice Alert (BPA) at Point-of-Care for Recruitment into a U.S.-Based Autism Research Study.

    Publication
  6. Stepped-care cognitive behavioral therapy in children on the autism spectrum with co-occurring anxiety.

    Publication
  7. A genetics-first approach to dissecting the heterogeneity of autism: Phenotypic comparison of autism risk copy number variants.

    Publication
  8. Evaluating two common strategies for research participant recruitment into autism studies: Observational study.

    Publication
  9. Beliefs about causes of autism and vaccine hesitancy among parents of children with autism spectrum disorder.

    Publication
  10. Language characterization in 16p11.2 deletion and duplication syndromes.

    Publication
  11. Evaluating heterogeneity in ASD symptomatology, cognitive ability, and adaptive functioning among 16p11.2 CNV carriers.

    Publication
  12. Vaccine hesitancy and attributions for autism among racially and ethnically diverse groups of parents of children with autism spectrum disorder: A pilot study.

    Publication
  13. Beliefs in vaccine as causes of autism among SPARK cohort caregivers.

    Publication
  14. Using latent class analysis to identify treatment-use subgroups among parents of children with autism spectrum disorder.

    Publication
  15. Psychiatric disorders in children with 16p11.2 deletion and duplication.

    Publication
  16. Gene disrupting mutations associated with regression in autism spectrum disorder.

    Publication
  17. Developmental trajectories for young children with 16p11.2 copy number variation.

    Publication
  18. Autism spectrum disorder, developmental and psychiatric features in 16p11.2 duplication.

    Publication
  19. The number of genomic copies at the 16p11.2 locus modulates language, verbal memory, and inhibition.

    Publication
  20. Brief report: Further examination of self-injurious behaviors in children and adolescents with autism spectrum disorders.

    Publication
  21. Clinical phenotype of the recurrent 1q21.1 copy-number variant.

    Publication
  22. Defining the effect of the 16p11.2 duplication on cognition, behavior, and medical comorbidities.

    Publication
  23. Self-motion perception in autism is compromised by visual noise but integrated optimally across multiple senses.

    Publication
  24. The cognitive and behavioral phenotype of the 16p11.2 deletion in a clinically ascertained population.

    Publication
  25. The role of parental cognitive, behavioral, and motor profiles in clinical variability in individuals with chromosome 16p11.2 deletions.

    Publication
  26. A multi-rater study on being teased among children/adolescents with autism spectrum disorder (ASD) and their typically developing siblings.

    Publication
  27. Psychotropic medication use among children with autism spectrum disorders within the Simons Simplex Collection: Are core features of autism spectrum disorder related?

    Publication
  28. Expression of the broad autism phenotype in simplex autism families from the Simons Simplex Collection.

    Publication
  29. Developmental regression among children with autism spectrum disorders: Onset, duration, and effects on functional outcomes.

    Publication
  30. A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders.

    Publication
  31. Utility of the Social Communication Questionnaire-Current and Social Responsiveness Scale as teacher-report screening tools for autism spectrum disorders.

    Publication
  32. Emotional and behavioral adjustment in typically developing siblings of children with autism spectrum disorders.

    Publication
  33. A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism.

    Publication
  34. Relationship between the social functioning of children with autism spectrum disorders and their siblings’ competencies/problem behaviors.

    Publication
  35. A multisite study of the clinical diagnosis of different autism spectrum disorders.

    Publication

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