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  1. Nutrition, longevity and disease: From molecular mechanisms to interventions

    Publication
    Diet as a whole, encompassing food composition, calorie intake, and the length and frequency of fasting periods, affects the time span in which health and functional capacity are …

  2. Resilience integrates concepts in aging research

    Publication
    Aging research is unparalleled in the breadth of disciplines it encompasses, from evolutionary studies examining the forces that shape aging to molecular studies uncovering the underlying mechanisms of …

  3. Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice

    Publication
    The loss of skeletal muscle function with age, known as sarcopenia, significantly reduces independence and quality of life and can have significant metabolic consequences. Although exercise is effective …

  4. Can we make drug discovery targeting fundamental mechanisms of aging a reality?

    Publication

  5. Can we make drug discovery targeting fundamental mechanisms of aging a reality?

    Publication

  6. Can we make drug discovery targeting fundamental mechanisms of aging a reality?

    Publication

  7. Fasting blood glucose as a predictor of mortality: Lost in translation

    Publication
    Aging leads to profound changes in glucose homeostasis, weight, and adiposity, which are considered good predictors of health and survival in humans. Direct evidence that these age-associated …

  8. Rhesus monkeys as a translational model for late-onset Alzheimer's disease

    Publication
    Age is a major risk factor for late-onset Alzheimer's disease (AD) but seldom features in laboratory models of the disease. Furthermore, heterogeneity in size and density …

  9. Cell-to-cell variation in gene expression and the aging process

    Publication
    There is tremendous variation in biological traits, and much of it is not accounted for by variation in DNA sequence, including human diseases and lifespan. Emerging evidence points …