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  1. Spontaneous behaviour is structured by reinforcement without explicit reward

    Publication

  2. ​​Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction

    Publication
    Animals both explore and avoid novel objects in the environment, but the neural mechanisms that underlie these behaviors and their dynamics remain uncharacterized. Here, we used multi-point …

  3. A transcriptional rheostat couples past activity to future sensory responses

    Publication
    Animals traversing different environments encounter both stable background stimuli and novel cues, which are thought to be detected by primary sensory neurons and then distinguished by downstream brain …

  4. Internal state: dynamic, interconnected communication loops distributed across body, brain, and time

    Publication

  5. Flexible scaling and persistence of social vocal communication

    Publication
    Innate vocal sounds such as laughing, screaming or crying convey one's feelings to others. In many species, including humans, scaling the amplitude and duration of vocalizations is …

  6. Systems Neuroscience of Natural Behaviors in Rodents

    Publication
    Animals evolved in complex environments, producing a wide range of behaviors, including navigation, foraging, prey capture, and conspecific interactions, which vary over timescales ranging from milliseconds to days …

  7. Revealing the structure of pharmacobehavioral space through motion sequencing

    Publication
    Understanding how genes, drugs and neural circuits influence behavior requires the ability to effectively organize information about similarities and differences within complex behavioral datasets. Motion Sequencing (MoSeq) is …

  8. Finding the Brain in the Nose

    Publication
    Olfaction is fundamentally distinct from other sensory modalities. Natural odor stimuli are complex mixtures of volatile chemicals that interact in the nose with a receptor array that, in …

  9. Structure and flexibility in cortical representations of odour space

    Publication
    The cortex organizes sensory information to enable discrimination and generalization1-4. As systematic representations of chemical odour space have not yet been described in the olfactory cortex, it …

  10. The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection

    Publication
    Many naturalistic behaviors are built from modular components that are expressed sequentially. Although striatal circuits have been implicated in action selection and implementation, the neural mechanisms that compose …

  11. Computational Neuroethology: A Call to Action.

    Publication
    The brain is worthy of study because it is in charge of behavior. A flurry of recent technical advances in measuring and quantifying naturalistic behaviors provide an important …

  12. The striatum specifies the statistics of behavior.

    Publication

  13. Q&A: Understanding the composition of behavior.

    Publication
    Understanding the brain requires understanding behavior. New machine vision and learning techniques are poised to revolutionize our ability to analyze behaviors exhibited by animals in the laboratory. Here …

  14. The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection.

    Publication
    Many naturalistic behaviors are built from modular components that are expressed sequentially. Although striatal circuits have been implicated in action selection and implementation, the neural mechanisms that compose …