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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
  • Research News
  • Funding Announcements
  • Newsletter Sign Up
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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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  • Presidential Lectures
  • Presents
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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  • Simons Collaboration on Localization of Waves
  • Simons Collaboration on Plasticity and the Aging Brain
  • Simons Collaboration on Principles of Microbial Ecosystems
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Science, Society & Culture
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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Patterns and correlates of two-year changes in depressive symptoms for autistic adults.

    Publication
  2. Self-reported everyday sources of happiness and unhappiness in autistic adults.

    Publication
  3. Perspectives on employer-initiated terminations among young adults on the autism spectrum.

    Publication
  4. Associations between social activities and depressive symptoms in adolescents and young adults with autism spectrum disorder: Testing the indirect effects of loneliness.

    Publication
  5. Patterns of sleep disturbances and associations with depressive symptoms in autistic young adults.

    Publication
  6. Behavioral responses to fevers and other medical events in children with and without ASD.

    Publication
  7. Developmental variability in autism across 17000 autistic individuals and 4000 siblings without an autism diagnosis: Comparisons by cohort, intellectual disability, genetic etiology, and age at diagnosis.

    Publication
  8. Bias in measurement of autism symptoms by spoken language level and non-verbal mental age in minimally verbal children with neurodevelopmental disorders.

    Publication
  9. The female protective effect against autism spectrum disorder.

    Publication
  10. Patterns of delay in early gross motor and expressive language milestone attainment in probands with genetic conditions versus idiopathic ASD from SFARI registries.

    Publication
  11. Patterns and correlates of two-year changes in depressive symptoms for autistic adults.

    Publication
  12. Prevalence of returnable genetic results based on recognizable phenotypes among children with autism spectrum disorder.

    Publication
  13. Perceived helpfulness of depression treatments among young adults with autism.

    Publication
  14. Sex differences in scores on standardized measures of autism symptoms: A multisite integrative data analysis.

    Publication
  15. Language characterization in 16p11.2 deletion and duplication syndromes.

    Publication
  16. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.

    Publication
  17. Identification of developmental and behavioral markers associated with genetic abnormalities in autism spectrum disorder.

    Publication
  18. Subdimensions of social-communication impairment in autism spectrum disorder.

    Publication
  19. Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci.

    Publication
  20. Understanding the gap between cognitive abilities and daily living skills in adolescents with autism spectrum disorders with average intelligence.

    Publication
  21. Behavioral and cognitive characteristics of females and males with autism in the Simons Simplex Collection.

    Publication
  22. Subcategories of restricted and repetitive behaviors in children with autism spectrum disorders.

    Publication
  23. Factors influencing scores on the Social Responsiveness Scale.

    Publication
  24. Exploring the relationship between anxiety and insistence on sameness in autism spectrum disorders.

    Publication
  25. Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders.

    Publication
  26. A multisite study of the clinical diagnosis of different autism spectrum disorders.

    Publication

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