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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. New Causes of Autism Found in ‘Junk’ DNA

    May 27, 2019
    The neurodevelopmental condition can result from mutations in the noncoding regions of the human genome, new research demonstrates for the first time.
  2. How ALS Progresses on Genetic and Cellular Level Revealed by High-Res Spinal Cord Study

    April 4, 2019
    The new findings offer potential avenues for developing therapies for amyotrophic lateral sclerosis.
  3. Open-Source Software Tracks Neural Activity in Real Time

    February 28, 2019
    The tool, called CaImAn, replaces the process of manually tracking the location and activity of neurons.
  4. Scientists Provide New Insight on How the Nose Adapts to Smells

    February 26, 2019
    First-of-its-kind study could aid research into how our sense of smell is affected by the decreasing number of neurons in our noses as we age.
  5. Gravitational Waves Will Settle Cosmic Conundrum

    February 14, 2019
    … the same values, which means our standard cosmological model might be flawed.” Feeney, Peiris and colleagues developed a universally applicable technique that calculates how gravitational wave data …
  6. Noncoding Mutations Contribute to Autism Risk

    December 13, 2018
    Genome-wide analysis the first to uncover a role for mutations in the noncoding portion of the genome in any human condition
  7. Enormous ‘Ghost’ Galaxy Spotted on Outskirts of Milky Way

    November 13, 2018
    The newfound dwarf galaxy, Antlia 2, is the largest known satellite of the Milky Way and the sparsest galaxy ever seen.
  8. DNA ‘Dances’ in First Explanation of How Genetic Material Flows Through a Nucleus

    October 25, 2018
    Finding reveals the large-scale movement of genetic material through the nucleus of a working cell.
  9. Pint-Size Planetary Systems Aren’t Into Heavy Metal

    October 24, 2018
    … type of planetary system, making them an ideal place to search for life on other planets. “Low-metallicity stars have been around a lot longer,” Brewer says …
  10. Flatiron Institute Launches Center for Computational Mathematics

    October 1, 2018
    … units came up with computational mathematics, I was dubious at first but was gradually persuaded that such a unit would act like glue, holding the whole institute …
  11. Elusive Origin of Stellar Geysers Revealed by 3D Simulations

    September 26, 2018
    Supersize eruptions of some of the biggest, brightest stars in the universe result from clumps of helium-rich material launched spaceward by intense light, simulations suggest
  12. Particles Surf Their Own Waves, Reveal How Microbes and Cells Move Through Human Body

    September 17, 2018
    New calculations and experiments show how balls ‘catch a wave’ when falling through viscous liquid near a flexible rubber sheet
  13. AI Accurately Predicts Effects of Genetic Mutations in Biological Dark Matter

    July 16, 2018
    The new deep learning technique could help researchers identify the genetic origin of diseases and better understand how evolution shaped our genes
  14. The Gaia Sausage: The Major Collision That Changed the Milky Way Galaxy

    July 4, 2018
    … Astronomy, University of Cambridge, U.K. ([email protected]) Sergey Koposov, Department of Physics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA ([email protected]) Alis Deason, Department …
  15. Assembly of Massive Galaxy Cluster Witnessed for the First Time

    April 25, 2018
    A dense flock of 14 galaxies from 1.4 billion years after the Big Bang is destined to become one of the most massive structures in the modern …
  16. Hubble Telescope Reveals Source of Gas Streaming Into Milky Way

    March 22, 2018
    The Leading Arm of the Magellanic Stream originates primarily from a nearby dwarf galaxy called the Small Magellanic Cloud
  17. Artificial Intelligence Techniques Reconstruct Mysteries of Quantum Systems

    February 26, 2018
    New machine learning techniques can help experimentalists probe systems of particles exponentially faster than conventional, brute-force techniques
  18. Stratospheric Ozone at Lower Latitudes Is Not Recovering, Despite Antarctic Ozone Hole Healing

    February 6, 2018
    … developed here can be used in many scientific applications that look at complex datasets.” Information for Press For additional information, please contact [email protected]. Scientific Contact …
  19. New Universe Simulation Reveals High-Resolution Details About Cosmological Structures

    January 31, 2018
    An international team of astrophysicists has released IllustrisTNG, the most advanced universe model of its kind.
  20. Newly Discovered Goliath Galaxies From Early Universe Hint at Massive Dark Matter Trove

    December 6, 2017
    The colossal clump of dark matter is nearly as large as physically possible at the time
  21. Flatiron Institute’s David Spergel Awarded 2018 Breakthrough Prize for Mapping the Early Universe

    December 3, 2017
    … about the universe, such as the nature of dark energy,” Spergel says. Spergel and Page are currently part of the Simons Observatory project, which will look for …
  22. Gravitational Waves From Merging Supermassive Black Holes Will Be Spotted Within 10 Years, New Study Predicts

    November 13, 2017
    Survey of fast-spinning pulsar stars offers better estimate of when astronomers will first detect the strongest gravitational waves in the universe, which dwarf those previously detected from …
  23. A Star That Devoured Its Own Planets

    October 12, 2017
    Astrophysicists estimate that the sunlike star called Kronos has consumed 15 Earths’ worth of rocky material
  24. Flatiron Scientists — With Help From the Public — Study Connection Between Body Bacteria and Autoimmune Disease

    September 26, 2017
    IBM’s World Community Grid has teamed up with the Flatiron Institute, Broad Institute of MIT and Harvard, Massachusetts General Hospital and the University of California, San Diego.
  25. Gov. Andrew Cuomo Joins Jim and Marilyn Simons to Dedicate Flatiron Institute

    September 7, 2017
    The new institute drives scientific discovery using computational methods.
  26. Antoine Georges to Lead New Center for Computational Quantum Physics

    January 6, 2017
    … for Computational Quantum Physics (CCQ), in the foundation’s new Flatiron Institute, and the appointment of Antoine Georges as its director. A new era is dawning in …
  27. David Spergel To Lead New Center for Computational Astrophysics

    November 9, 2015
    … and serve as a focal point for computational astronomy around the world. David Spergel is the Charles A. Young Professor of Astronomy on the Class of 1897 …
  28. Leslie Greengard Named Director, Simons Center for Data Analysis

    September 3, 2013
    … M.D. and Ph.D. in computer science from Yale University and has been on the faculty of the Courant Institute of Mathematical Sciences at New York …
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