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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
  • Research News
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  • Newsletter Sign Up
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  • Media Relations

We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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  • Presidential Lectures
  • Presents
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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  • Simons Collaboration on Principles of Microbial Ecosystems
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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Structural & Molecular Biophysics Group Meeting

    Meeting
  2. Genomics Group Meeting

    Meeting
  3. Biophysical Modeling Group Meeting

    Meeting
  4. CCBx CryoEM/ET Meeting

    Meeting
  5. Developmental Dynamics Group Meeting

    Meeting
  6. CCB Seminar: Sarah L. Keller, Ph.D.

    Seminar
    Sarah L. Keller, Ph.D., University of Washington – Seattle  Vacuole Membranes of Hungry Yeast are Tiny, Living, Phase-Separating Thermostats Liquid-liquid phase separation in living biological membranes …
  7. Developmental Dynamics Group Meeting

    Meeting
  8. Biological Transport & Networks Group Meeting

    Meeting
  9. CCB Brown Bag Seminar

    Seminar
  10. Biomolecular Design Group Meeting

    Meeting
  11. Computer Vision & Machine Learning Meeting

    Meeting
  12. Genomics Group Meeting

    Meeting
  13. CCBx Neuro Meeting

    Meeting
  14. Structural & Molecular Biophysics Group Meeting

    Meeting
  15. Biophysical Modeling Group Meeting

    Meeting
  16. CCBx CryoEM/ET Meeting

    Meeting
  17. Developmental Dynamics Group Meeting

    Meeting
  18. CCB Seminar: Jan-Michael Peters, Ph.D.

    Seminar
    … Cell Rep. 2025). The length and lifetime of loops formed by cohesin (‘cohesin loops’) is limited by WAPL, which can release cohesin from chromatin (Kueng, Cell 2006 …
  19. Genomics Group Meeting

    Meeting
  20. CCB Colloquium: Margaret Gardel, Ph.D.

    Seminar
    Margaret Gardel, Ph.D., University of Chicago Mechanical Information Processing in Adherent Cells My lab studies how the movement and shape of living cells is controlled by living …
  21. CCB Seminar: Vera Moiseenkova-Bell, Ph.D.

    Seminar
    … Together, these studies identify a ligandable TRPV2 pocket that tunes gating and provide an in situ framework to relate TRP channel pharmacology to native lysosomal membrane architecture …
  22. CCB Seminar: Yuanzhao Zhang, Ph.D.

    Seminar
    Yuanzhao Zhang, Ph.D., Santa Fe Institute Physics-Uninformed Machine Learning How much can we learn about a dynamical system when models are unavailable and data is limited …
  23. Developmental Dynamics Group Meeting

    Meeting
  24. CCB Brown Bag Seminar

    Seminar
  25. CCB Brown Bag Seminar

    Seminar
  26. CCB Brown Bag Seminar

    Seminar
  27. Genomics Group Meeting

    Meeting
  28. Structural & Molecular Biophysics Group Meeting

    Meeting
  29. Biophysical Modeling Group Meeting

    Meeting
  30. Developmental Dynamics Group Meeting

    Meeting
  31. CCB Seminar: Viviana Risca, Ph.D.

    Seminar
    Viviana Risca, Ph.D., Rockefeller University Probing Sub-kilobase Chromatin Fiber Folding and its Regulation The kilobase-scale architecture of chromatin effectively defines the epigenomic landscape on which …
  32. Computer Visionaries Interest Group Meeting

    Meeting
  33. Structural & Molecular Biophysics Group Meeting

    Meeting
  34. Genomics Group Meeting

    Meeting
  35. Biophysical Modeling Group Meeting

    Meeting
  36. CCB Seminar: Joe Howard, Ph.D.

    Seminar
    Joe Howard, Ph.D., Yale University Branching Morphogenesis of Dendrites The highly elaborated branched morphologies of dendrites are responsible for the enormous diversity of neuronal cell types in …
  37. Developmental Dynamics Group Meeting

    Meeting
  38. CCB Seminar: William Irvine, Ph.D.

    Seminar
    William Irvine, Ph.D., University of Chicago Quiet Within, Chaos Without: Harnessing Turbulence for Function Across Scales Turbulence is synonymous with chaos, yet its velocity fluctuations are structured …
  39. Genomics Group Meeting

    Meeting
  40. Computer Visionaries Interest Group Meeting

    Meeting
  41. Structural & Molecular Biophysics Group Meeting

    Meeting
  42. Biophysical Modeling Group Meeting

    Meeting
  43. Developmental Dynamics Group Meeting

    Meeting
  44. CCB Seminar: Antonio Costa, Ph.D.

    Seminar
    Antonio C. Costa | Paris Brain Institute, Sorbonne University  Comparing Dynamical Systems from Data: A Multiscale Approach Variability across realizations of dynamical systems is a hallmark of complexity, appearing …
  45. Computer Visionaries Interest Group Meeting

    Meeting
  46. Structural & Molecular Biophysics Group Meeting

    Meeting
  47. Genomics Group Meeting

    Meeting
  48. Biophysical Modeling Group Meeting

    Meeting
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