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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
  • Research News
  • Funding Announcements
  • Newsletter Sign Up
  • Press Releases
  • Media Relations

We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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  • Public Events
  • Presidential Lectures
  • Presents
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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

  • All Open Positions
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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  • Autism
  • Neuroscience
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  • Ecology & Evolution
  • Plant Biology
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  • Computational Datasets
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  • Simons Collaboration on Localization of Waves
  • Simons Collaboration on Plasticity and the Aging Brain
  • Simons Collaboration on Principles of Microbial Ecosystems
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Autism & Neuroscience
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Science, Society & Culture
  • Scientific Software Research Faculty Award
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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Unraveling Bacterial Swimming: Insights from Mathematical Modeling, Simulations, and Experiments

    Seminar
    Abstract Flagella-driven motility is a widespread strategy by which microorganisms navigate complex aqueous environments. Swimming cells must not only generate propulsion but also respond to, and interact …
  2. From Cryo-EM Structures to AI-Powered Predictions of Amyloid Formation

    Seminar
    Abstract The propensity of proteins to form amyloid fibrils is encoded in their amino acid sequences, motivating the development of computational methods to predict amyloidogenicity directly from sequence …
  3. CCB Seminar: François Gallaire, Ph.D.

    Seminar
  4. CCB Colloquium: Andrea Califano, Ph.D.

    Colloquium
  5. Biomolecular Design Group Meeting

    Meeting
  6. COMPASS Meeting

    Meeting
  7. CCBx Annual Meeting

    Meeting
  8. Developmental Dynamics Group Meeting

    Meeting
  9. Brown Bag Seminar

    Seminar
    Speakers TBA.
  10. Biomolecular Design Group Meeting

    Meeting
  11. Genomics Group Meeting

    Meeting
  12. COMPASS Meeting

    Meeting
  13. Biophysical Modeling Group Meeting

    Meeting
  14. Developmental Dynamics Group Meeting

    Meeting
  15. Biomolecular Design Group Meeting

    Meeting
  16. COMPASS Meeting

    Meeting
  17. Genomics Group Meeting

    Meeting
  18. Biophysical Modeling Group Meeting

    Meeting
  19. Biomolecular Design Group Meeting

    Meeting
  20. COMPASS Meeting

    Meeting
  21. Biophysical Modeling Group Meeting

    Meeting
  22. Biomolecular Design Group Meeting

    Meeting
  23. COMPASS Meeting

    Meeting
  24. Genomics Group Meeting

    Meeting
  25. Biophysical Modeling Group Meeting

    Meeting
  26. Developmental Dynamics Group Meeting

    Meeting
  27. Quantitative Travels Through Autism Data

    Seminar
  28. Seminar: Daryl Klein, MD, Ph.D.

    Seminar
    Speaker: Daryl Klein, MD, Ph.D., Yale School of Medicine Title: Mechanisms to Medicines: Structural Blueprints for Targeting Receptor Signaling Cell-surface receptors are often interpreted through canonical …
  29. Developmental Dynamics Group Meeting

    Meeting
  30. Colloquium: Christina Leslie, Ph.D.

    Seminar
    Speaker: Christina Leslie, Ph.D., Memorial Sloan Kettering Cancer Center Title: AI Models for Regulatory Genomics and Spatial Biology We will present new ML/AI models for single …
  31. Biomolecular Design Group Meeting

    Meeting
  32. COMPASS Meeting

    Meeting
  33. Genomics Group Meeting

    Meeting
  34. Biophysical Modeling Group Meeting

    Meeting
  35. Developmental Dynamics Group Meeting

    Meeting
  36. Brown Bag Seminar

    Seminar
    … α- and β-CTTs favor interactions oriented toward the microtubule minus end: the α-CTT preferentially interacts with the β-tubulin in the neighboring dimer in the …
  37. Genomics Group Meeting

    Meeting
  38. COMPASS Meeting

    Meeting
  39. Developmental Dynamics Group Meeting

    Meeting
  40. Seminar: Marla Sokolowski, Ph.D.

    Seminar
    Speaker: Marla Sokolowski, Ph.D. (University of Toronto) Title: Should I Stay or Should I Go?  Unravelling Gene-environment Interplay in Behavior We are interested in how DNA …
  41. Biomolecular Design Group Meeting

    Meeting
  42. COMPASS Meeting

    Meeting
  43. Genomics Group Meeting

    Meeting
  44. Biophysical Modeling Group Meeting

    Meeting
  45. Developmental Dynamics Group Meeting

    Meeting
  46. Colloquium: Victor Sourjik, Ph.D.

    Seminar
    Speaker: Victor Sourjik, Ph.D. (Max Planck Institute For Terrestrial Microbiology) Title: How physics guides evolution: Lessons from bacterial motility Bacterial motility is one of the quantitatively best …
  47. Genomics Group Meeting

    Meeting
  48. Computer Vision & Machine Learning Meeting

    Meeting
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