Autism Rat Models Consortium: Publications
From ARC
Results
-
The ubiquitin system: A regulatory hub for intellectual disability and autism spectrum disorder.
-
Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.
-
Developmental loss of MeCP2 from VIP interneurons impairs cortical function and behavior.
-
Social attention in autism: Neural sensitivity to speech over background noise predicts encoding of social information.
-
Clinical impact of splicing in neurodevelopmental disorders.
-
Is motor impairment in autism spectrum disorder distinct from developmental coordination disorder? A report from the SPARK study.
-
Enhancing WNT signaling restores cortical neuronal spine maturation and synaptogenesis in Tbr1 mutants.
-
Social camouflaging in autistic and neurotypical adolescents: A pilot study of differences by sex and diagnosis.
-
SCN2A channelopathies in the autism spectrum of neuropsychiatric disorders: A role for pluripotent stem cells?
-
Whole-genome and RNA sequencing reveal variation and transcriptomic coordination in the developing human prefrontal cortex.
-
Use of longitudinal EEG measures in estimating language development in infants with and without familial risk for autism spectrum disorder.
-
Co-localization between sequence constraint and epigenomic information improves interpretation of whole-genome sequencing data.
-
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles.
-
The network structure of irritability and aggression in individuals with autism spectrum disorder.
-
Recurrent homozygous damaging mutation in TMX2, encoding a protein disulfide isomerase, in four families with microlissencephaly.
-
Randomized crossover feasibility trial of helminthic Trichuris suis ova versus placebo for repetitive behaviors in adult autism spectrum disorder.
-
FMRP control of ribosome translocation promotes chromatin modifications and alternative splicing of neuronal genes linked to autism.
-
Accuracy of short tandem repeats genotyping tools in whole exome sequencing data.
-
The general impact of haploinsufficiency on brain connectivity underlies the pleiotropic effect of neuropsychiatric CNVs.
-
The oft-overlooked massively parallel reporter assay: Where, when, and which psychiatric genetic variants are functional?
-
Autism-misregulated eIF4G microexons control synaptic translation and higher order cognitive functions.
-
Cortical Foxp2 supports behavioral flexibility and developmental dopamine D1 receptor expression.
-
Forecasting risk gene discovery in autism with machine learning and genome-scale data.
-
Social stimuli induce activation of oxytocin neurons within the paraventricular nucleus of the hypothalamus to promote social behavior in male mice.
-
Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation.
-
Interneuron transplantation rescues social behavior deficits without restoring wild-type physiology in a mouse model of autism with excessive synaptic inhibition.
-
Single-cell analysis of Foxp1-driven mechanisms essential for striatal development.
-
Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants.
-
Autism heterogeneity in a densely sampled U.S. population: Results from the first 1,000 participants in the RI-CART study.
-
Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice.
-
Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder.
-
Natural selection influenced the genetic architecture of brain structure, behavioral and neuropsychiatric traits.
-
Maternal experience-dependent cortical plasticity in mice is circuit- and stimulus-specific and requires MECP2.
-
Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model.
-
Beliefs in vaccine as causes of autism among SPARK cohort caregivers.
-
Exploring the familial role of social responsiveness differences between savant and non-savant children with autism.
-
Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism.
-
Usp9X controls ankyrin-repeat domain protein homeostasis during dendritic spine development.
-
Mechanisms underlying gain modulation in the cortex.
-
Psychotic symptoms in 16p11.2 copy-number variant carriers.
-
Using multiple measurements of tissue to estimate cell-type-specific gene expression via deconvolution.
-
Animal functional magnetic resonance imaging: Trends and path toward standardization.
-
Autism spectrum disorder.
-
Partial loss of USP9X function leads to a male neurodevelopmental and behavioral disorder converging on transforming growth factor beta signaling.
-
A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency.
-
Synaptic dysfunction in human neurons with autism-associated deletions in PTCHD1-AS.
-
Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis.
-
Towards neurosubtypes in autism.