SFARI Gene update

July 22, 2016

New data were added to SFARI Gene in June. This data release included the addition of new human genes implicated in autism, new animal models, and new protein-protein and protein-nucleic-acid interactions of relevance for autism.

Autism Research Initiative (SFARI)

Colorful chromosomes spill out from a larger, multicolored sphere against a black background, representing a cell and its genetic material seen under a microscope. — Thomas Ried, NCI/Science Source Thomas Ried, NCI/Science Source

New data were added to SFARI Gene in June. Some of the highlights of this data release include:

1 new gene (BCKDK) was added to Category 2 of the Gene Scoring Module. This brings the total number of autism-risk genes with strong evidence to 55 (ie. Categories 1 and 2 ranked genes).
14 new genes were added to Category 3, bringing the total number of genes with suggestive evidence for a role in autism to 136.
The mouse model dataset has been updated with 54 new models.
The rat model dataset has been updated with 32 new models.
Over 1,000 new protein interactions of genes associated with autism have been added to the Protein Interaction Module.