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Saul Villeda headshot.
Saul Villeda headshot.

Awardee

Saul Villeda, Ph.D.

Investigator, Simons Collaboration on Plasticity and the Aging Brain

Affiliations
  • Associate Professor, Department of Anatomy, University of California, San Francisco
  • Associate Director, Bakar Aging Research Institute, University of California, San Francisco
Website
villedalab.ucsf.edu

Publications

Blood-to-brain communication in aging and rejuvenation

Nat Neurosci, January 16, 2023

G Bieri, AB Schroer, and S. Villeda

Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function

Cell Rep, November 8, 2022

KJB Pratt, JM Shea, L Remesal-Gomez, G Bieri, LK Smith, J Couthouis, et al.

Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits

Sci Adv, May 6, 2022

D Yu, T Li, JC Delpech, B Zhu, P Kishore, T Koshi, et al.

Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions

J Exp Med, July 5, 2021

TT Ho, PV Dellorusso, EV Verovskaya, ST Bakker, J Flach, LK Smith, et al.

Projects

Fluorescent microscopy image of brain tissue showing blue, green, and red stained neural cells and fibers, with dense cell clusters and branching structures against a dark background.

Plasticity and the Aging Brain

Simons Collaboration
Coleen Murphy - Celegans

Conserved regulatory pathways in age-related loss of plasticity and cognitive function

Funded Work
Link molecules, circuits and behavior to promote memory from Loren Frank

Linking molecules, circuits and behavior to promote plasticity and memory in the aging brain

Funded Work
Neurons Vasculature

Understanding how bloodborne factors improve the function of the aging brain

Funded Work

Featuring Saul Villeda

Illustration of a brain and liver connected by a healthy vine, with little people exercising and reading scattered throughout.

A Liver Enzyme Produced During Exercise Might Reverse Memory Loss

Blood platelets releasing orange factor to the brain

Research Converging on How Young Blood Improves Old Brains

mouse wearing glasses and mouse with a walker

The Challenges of Studying Elderly Animals

Glial cells, which surround the blood vessels, are shown in green. Neurons are shown in red

Searching for the Secret of How Young Blood Rejuvenates the Brain

Events

Can Aging be Reversed in the Brain?

Lecture

April 14, 2021

5–6:15 p.m. ET

Speaker

Saul Villeda

Saul Villeda headshot.

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Neuroscience Collaborations

Simons Collaborations in Neuroscience unite leading scientists to tackle fundamental questions about brain function, focusing on areas newly opened by major advances.

Learn more
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