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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  1. Loss of Tsc1 in Striatal Neurons May Contribute to Altered Motor Behaviors in Tuberous Sclerosis Complex and Autism

    June 28, 2022
  2. Machine-Learning Model Provides Estimates of Cognitive Ability for Large-Scale Autism Studies

    June 28, 2022
  3. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    June 7, 2022
  4. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    May 27, 2022
  5. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    May 12, 2022
  6. Altered Immune Molecules During Pregnancy and in the Umbilical Cord at Birth Predict Later Autism Diagnoses

    April 29, 2022
  7. Synaptic Imbalance and Disrupted Homeostatic Plasticity in Cortical Circuits of Chd8 Haploinsufficient Mice

    April 29, 2022
  8. Alterations in Sound Processing in Cntnap2 Rats Provide Insights Into Mechanisms of Language-Related Disorders

    April 29, 2022
  9. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    April 28, 2022
  10. New Genetic Analyses Provide Estimates of De Novo Mutations in Low– and High–Risk Families With Autism

    April 18, 2022
  11. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    April 4, 2022
  12. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    March 29, 2022
  13. New Model Shows How Cilia Make Waves

    March 17, 2022
  14. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    March 3, 2022
  15. Study Finds Placental Hormone Is Critical for Fetal Brain Development

    February 24, 2022
  16. Human Derived 3D Brain Cultures Provide Insights Into Brain Size Changes in 16p11.2 Conditions

    February 24, 2022
  17. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    February 24, 2022
  18. New Study Supports Role for Disruptions in Synapse Development and Function in ASD

    February 23, 2022
  19. Origin of Supermassive Black Hole Flares Identified: Largest-Ever Simulations Suggest Flickering Powered by Magnetic ‘Reconnection’

    February 3, 2022
  20. ‘Quantum Friction’ Slows Water Flow Through Carbon Nanotubes, Resolving Long-Standing Fluid Dynamics Mystery

    February 2, 2022
  21. Theorists and Experimentalists Join Forces To Explore Nature’s ‘Third Kingdom’ of Particles

    January 31, 2022
  22. Patchy Expression of Pcdh19 in Female Mice Causes Defects in Hippocampal Neuron Presynaptic Development Signaling and Memory Processing

    January 28, 2022
  23. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    January 28, 2022
  24. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    January 27, 2022
  25. High-Resolution Rodent Movement Tracking Provides the Opportunity To Link Autism Risk Genes With Behavioral Presentations

    January 26, 2022
  26. A Machine-Learning Framework for Prioritizing Disease-Associated Enhancers

    January 25, 2022
  27. The Largest Suite of Cosmic Simulations for AI Training Is Now Free To Download; Already Spurring Discoveries

    January 6, 2022
  28. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    December 25, 2021
  29. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    December 23, 2021
  30. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    December 22, 2021
  31. Reaching Across the Aisle To Find the Algorithms of Vision

    December 22, 2021
  32. A ‘Forest Fire’ Model of Cell Division Can Explain Clonal Dominance in Developing Tissue

    December 14, 2021
  33. SFARI Gene To Introduce EAGLE, a New ASD-Relevance Gene Scoring System

    December 10, 2021
  34. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    November 30, 2021
  35. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    November 30, 2021
  36. Hippocampal Replay: Reflection on the Past or Planning for the Future?

    November 30, 2021
  37. Altered Hormone Signaling in the Brainstem Causes Motor Delays in 16p11.2 Mice

    November 22, 2021
  38. RhoA Overactivation May Underlie Smaller Brain Volumes in Cul3 Mutant Mice

    November 16, 2021
  39. Tandem Repeat Mutations in Autism

    November 16, 2021
  40. Paradoxical Material a Mashup of Three Different Phases at Once, Quantum Physicists Find

    November 10, 2021
  41. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    October 27, 2021
  42. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    October 27, 2021
  43. Astrophysicists Reveal Largest-Ever Suite of Universe Simulations

    October 24, 2021
  44. Perceptual Impairments and Altered Excitatory–Inhibitory Activity in Cntnap2 Knockout Mice

    September 30, 2021
  45. Fetal Responses to Maternal Infection May Help Explain Prevalence of Autism in Males

    September 30, 2021
  46. Study Using SPARK Data Uncovers New Inherited Genetic Risks for Autism

    September 28, 2021
  47. Probing the Neural Circuits of Social Interactions in Monkeys

    September 28, 2021
  48. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    September 15, 2021
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