Amit Singer is one of the leaders in the mathematical analysis of noisy data provided by cryo-EM.
Singer is a professor of mathematics and a member of the executive committee of the Program in Applied and Computational Mathematics (PACM) at Princeton University. He joined Princeton as an assistant professor in 2008. From 2005 to 2008 he was a Gibbs Assistant Professor in Applied Mathematics at the Department of Mathematics, Yale University.
Singer received his B.Sc. degree in Physics and Mathematics and his Ph.D. degree in applied mathematics from Tel Aviv University, Israel, in 1997 and 2005, respectively. He was awarded the Moore Investigator in Data-Driven Discovery Award (2014), the Simons Investigator Award (2012), the Presidential Early Career Award for Scientists and Engineers (2010), the Alfred P. Sloan Research Fellowship (2010) and the Haim Nessyahu Prize in Mathematics (2007). His current research in applied mathematics focuses on theoretical and computational aspects of data science, and on developing computational methods for structural biology.
Singer works on a broad range of problems in applied mathematics, solving specific applied problems and employing sophisticated theory to allow the solution of general classes of problems. Among the areas to which he has contributed are diffusion maps, cryo-electron microscopy, random graph theory, sensor networks, graph Laplacians, and diffusion processes. His recent work in electron microscopy combines representation theory with a novel network construction to provide reconstructions of structural information on molecules from noisy two-dimensional images of populations of the molecule. He works with a widely varied group of collaborators and graduate students in several disciplines. His work is increasing the range of applicable mathematics.