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Portrait of SFARI Investigator Arnold Kriegstein.
Portrait of SFARI Investigator Arnold Kriegstein.

Awardee

Arnold Kriegstein, M.D., Ph.D.

SFARI Investigator

SFARI Scientific Review Board

Affiliations
  • Professor, Department of Neurology and Founding Director, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco

Publications

Single-cell proteomic landscape of the developing human brain.

Nat. Biotechnol., January 27, 2026

Wu T., Jiang L., Mukhtar T., Wang L., Jian R., Wang C., et al.

Single-cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.

Nat. Commun., July 4, 2025

Perez Y., Velmeshev D., Wang L., White M.L., Siebert C., Baltazar J., et al.

Molecular and cellular dynamics of the developing human neocortex at single-cell resolution.

Nature, January 8, 2025

Wang L., Wang C., Moriano J.A., Chen S., Zuo G., Cebrián-Silla A., et al.

Molecular and cellular dynamics of the developing human neocortex at single-cell resolution.

bioRxiv, August 4, 2024

Wang L., Wang C., Moriano J.A., Chen S., Zuo G., Cebrián-Silla A., et al.

Projects

High-resolution proteome mapping in the developing human cerebral cortex to uncover mutationally convergent pathways in autism

Awarded 2022
Colorful DNA sequencing chromatogram showing overlapping peaks and corresponding DNA base letters (A, T, C, G) on a black background, representing genetic data analysis.

Identifying altered gene regulatory networks at single-cell resolution along the trajectory of brain development in autism spectrum disorders

Awarded 2020
Laboratory scene with test tubes in a plastic rack, a pipette, glass vials, and a microscope on a data sheet background, all shown with a blue and yellow tint.

Integrated single-cell and functional analysis of Dup15q syndrome

Awarded 2019
Laboratory scene with test tubes in a plastic rack, a pipette, glass vials, and a microscope on a data sheet background, all shown with a blue and yellow tint.

Investigating cell-type-specific molecular pathology in autism

Awarded 2017

Featuring Arnold Kriegstein

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2022 Genomics of ASD: Pathways to Genetic Therapies Awardees Announced

Image of Multielectrode arrays (MEA)

SFARI 2020 Research Awardees Announced

Image of blue and pink and purple lines

Rethinking the Spectrum: Three Things We Thought Were True About Autism

Colorful clusters represent different brain cell types, each labeled with abbreviations and colors, surrounding a central blue area. The image maps cell diversity and distribution in the brain cortex.

Single-Nucleus RNA Sequencing Identifies Brain Cell Types With Significant Changes in Gene Expression in Autism

Events

Genomic insights into human cortical development and neurodevelopmental disease

Lecture

February 1, 2017

5–6 p.m. ET

Speaker

Arnold Kriegstein

Portrait of SFARI Investigator Arnold Kriegstein.

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Simons Foundation Autism Research Initiative (SFARI)

SFARI is the Simons Foundation’s autism research program, advancing the basic science of autism and related neurodevelopmental disorders through funding, collaboration, and open science.

Learn more
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