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Bringing people and ideas together to fund, conduct, and share transformative science.

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  1. Shader-Like Computations in WebGL for Advanced Graphics and General Purposes

    Institute of Electrical and Electronics Engineers, January 25, 2021

    A. Watters

  2. Targeted photostimulation uncovers circuit motifs supporting short-term memory

    Nat Neurosci., January 25, 2021

    K Daie, K. Svoboda, and S. Druckmann

  3. mRNA-1273 efficacy in a severe COVID-19 model: attenuated activation of pulmonary immune cells after challenge

    bioRxiv 2021.01.25.428136, January 25, 2021

    M. Meyer, Y. Wang, D. Edwards, G. Smith, A. Rubenstein, P. Ramanathan, et al.

  4. The Neural Representation of Force across Grasp Types in Motor Cortex of Humans with Tetraplegia

    eNeuro, January 22, 2021

    A Rastogi, FR Willett, J Abreu, DC Crowder, BA Murphy, WD Memberg, et al.

  5. Methods to investigate intrathecal adaptive immunity in neurodegeneration

    Mol Neurodegener, January 22, 2021

    H Oh, O Leventhal, D Channappa, VW Henderson, T. Wyss-Coray, B Lehallier, et al.

  6. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

    Mol Psychiatry, January 22, 2021

    X Jia, FA Goes, AE Locke, D Palmer, W Wang, S Cohen-Woods, et al.

  7. MVP predicts the pathogenicity of missense variants by deep learning.

    Nat. Commun., January 21, 2021

    Qi H., Zhang H., Zhao Y., Chen C., Long J.J., Chung W.K., et al.

  8. Pseudo-BCS wave function from density matrix decomposition: Application in auxiliary-field quantum Monte Carlo

    Physical Review Research, arxiv:2010.06055, January 21, 2021

    Zhi-Yu Xiao, H. Shi, and S. Zhang

  9. Incomplete Cell Sorting Creates Engineerable Structures with Long-Term Stability

    Cell Reports Physical Science, January 20, 2021

    J. Tordoff, M. Krajnc, N. Walczak, M. Lima, J. Beal, S. Shvartsman, et al.

  10. Decoding and perturbing decision states in real time

    Nature, January 20, 2021

    D Peixoto, JR Verhein, R. Kiani, JC Kao, P Nuyujukian, C Chandrasekaran, et al.

  11. Striatal activity topographically reflects cortical activity

    Nature, January 20, 2021

    AJ Peters, JMJ Fabre, N. Steinmetz, and M. Carandini

  12. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

    Nat Commun., January 20, 2021

    JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, D Cameron-Smith, et al.

  13. Unsupervised neural network models of the ventral visual stream

    Proc Natl Acad Sci U S A., January 19, 2021

    C Zhuang, S Yan, A Nayebi, M Schrimpf, MC Frank, J. DiCarlo, et al.

  14. Unsupervised neural network models of the ventral visual stream

    Proc Natl Acad Sci U S A, January 19, 2021

    C Zhuang, S Yan, A Nayebi, M Schrimpf, MC Frank, J. DiCarlo, et al.

  15. Protein-coding repeat polymorphisms strongly shape diverse human phenotypes

    bioRxiv, January 19, 2021

    RE Mukamel, RE Handsaker, MA Sherman, AR Barton, Y Zheng, S. McCarroll, et al.

  16. Mutations in spliceosomal genes PPIL1 and PRP17 cause neurodegenerative pontocerebellar hypoplasia with microcephaly.

    Neuron, January 19, 2021

    Chai G., Webb A., Li C., Antaki D., Lee S., Breuss M.W., et al.

  17. STENCIL-NET: Data-driven solution-adaptive discretization of partial differential equations

    arxiv:2101.06182, January 18, 2021

    Suryanarayana Maddu, Dominik Sturm, Bevan L Cheeseman, C. Müller, and Ivo F Sbalzarini

  18. Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk

    Nature Genetics, January 18, 2021

    C. Park, J. Zhou, A. Wong, K. Chen, C. Theesfeld, R. Darnell, et al.

  19. A fast spectral method for electrostatics in doubly-periodic slit channels

    The Journal of Chemical Physics, arxiv:2101.07088, 2021

    Ondrej Maxian, Raul P. Peláez, L. Greengard, and Aleksandar Donev

  20. CaImAn an open source tool for scalable calcium imaging data analysis

    eLife, 2021

    J. Friedrich, P. Gunn, A. Giovannucci, J. Kalfon, B. Brown, S. Koay, et al.

  21. The geometry of neuronal representations during rule learning reveals complementary roles of cingulate cortex and putamen

    Neuron, January 16, 2021

    Y Cohen, E. Schneidman, and R Paz

  22. Excited states in variational Monte Carlo using a penalty method

    The Journal of Chemical Physics, arxiv:2009.13556, January 15, 2021

    Shivesh Pathak, B. Busemeyer, João N. B. Rodrigues, and L. Wagner

  23. Supporting generalization in non-human primate behavior by tapping into structural knowledge: Examples from sensorimotor mappings, inference, and decision-making

    Prog Neurobiol., January 14, 2021

    JP Noel, B Caziot, S Bruni, NE Fitzgerald, E Avila, and D. Angelaki

  24. From heterogeneous datasets to predictive models of embryonic development

    bioRxiv 2021.01.31.429006, January 13, 2021

    S. Dutta, A. Patel, S. Keenan, and S. Shvartsman

  25. Swirling Instability of the Microtubule Cytoskeleton

    Physical Review Letters, January 13, 2021

    D. Stein, G. De Canio, E. Lauga, M. Shelley, and R. Goldstein

  26. A Micromachined Picocalorimeter Sensor for Liquid Samples with Application to Chemical Reactions and Biochemistry

    Advanced Science, January 12, 2021

    Jinhye Bae, Juanjuan Zheng, and D. Needleman

  27. Topological Charge Pumping in Excitonic Insulators

    Physical Review Letters, arxiv:2008.00134, January 12, 2021

    Zhiyuan Sun and A. Millis

  28. Recurrent network dynamics shape direction selectivity in primary auditory cortex

    Nat Commun., January 12, 2021

    DA Aponte, G Handy, AM Kline, H Tsukano, B. Doiron, and HK Kato

  29. Patterns of de novo tandem repeat mutations and their role in autism.

    Nature, January 12, 2021

    Mitra I., Huang B., Mousavi N., Ma N., Lamkin M., Yanicky R., et al.

  30. Moiré metrology of energy landscapes in van der Waals heterostructures

    Nature Communications, arxiv:2008.04835, January 11, 2021

    D. Halbertal, Nathan R. Finney, Sai S. Sunku, Alexander Kerelsky, Carmen Rubio-Verdú, Sara Shabani, et al.

  31. Some recent developments in auxiliary-field quantum Monte Carlo for real materials

    The Journal of Chemical Physics, arxiv:2009.13585, January 11, 2021

    Shi, Hao and S. Zhang

  32. Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence

    Scientific Reports, January 11, 2021

    A. Neuwald, L. Hilakivi-Clarke, R. Clarke, and J. Xuan

  33. Lapses in perceptual decisions reflect exploration

    Elife, January 11, 2021

    S Pisupati, L Chartarifsky-Lynn, A Khanal, and A. Churchland

  34. Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence

    Scientific Reports, January 11, 2021

    J. Gu, A. Neuwald, L. Hilakivi-Clarke, R. Clarke, and J. Xuan

  35. Sensory over-responsivity is related to GABAergic inhibition in thalamocortical circuits.

    Transl. Psychiatry, January 11, 2021

    Wood E.T., Cummings K.K., Jung J., Patterson G., Okada N., Guo J., et al.

  36. Mapping of CSF transport using high spatiotemporal resolution dynamic contrast-enhanced MRI in mice: Effect of anesthesia

    Magn Reson Med., January 11, 2021

    EH Stanton, NDÅ Persson, RS Gomolka, T Lilius, B Sigurðsson, H Lee, et al.

  37. Efficient high-order accurate Fresnel diffraction via areal quadrature and the nonuniform FFT

    Journal of Astronomical Telescopes, Instruments, and Systems, arxiv:2010.05978, January 11, 2021

    A. Barnett

  38. A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: Guidelines from the Kidney Precision Medicine Project

    Physiological Genomics, January 11, 2021

    T El-Achkar, et al.

  39. JOINT for large-scale single-cell RNA-sequencing analysis via soft-clustering and parallel computing.

    BMC Genomics, January 10, 2021

    Cui T. and T. Wang

  40. Thousands of high-quality sequencing samples fail to show meaningful correlation between 5S and 45S ribosomal DNA arrays in humans.

    Sci. Rep., January 10, 2021

    Hall A.N., T. Turner, and Queitsch C.

  41. An “individualist” model of an active genome in a developing embryo

    bioRxiv, January 9, 2021

    S. Huang, S. Dutta, P. Whitney, S. Shvartsman, and C. Rushlow

  42. Quantum generative model for sampling many-body spectral functions

    Physical Review B, arxiv:1910.14213, January 8, 2021

    D. Sels and E. Demler

  43. Citric Acid Water as an Alternative to Water Restriction for High-Yield Mouse Behavior

    eNeuro, January 8, 2021

    AE Urai, V Aguillon-Rodriguez, IC Laranjeira, F Cazettes, International Brain Lab, Z. Mainen, et al.

  44. Wave functions, electronic localization, and bonding properties for correlated materials beyond the Kohn-Sham formalism

    Physical Review B, arxiv:2010.04694, January 6, 2021

    A. D. N. James, E. I. Harris-Lee, A. Hampel, M. Aichhorn, and S. B. Dugdale

  45. Multi-parametric analysis of 57 SYNGAP1 variants reveal impacts on GTPase signaling, localization, and protein stability.

    Am. J. Hum. Genet., January 6, 2021

    Meili F., Wei W.J., Sin W.-C., Meyers W.M., Dascalu I., Callaghan D.B., et al.

  46. Calcium imaging and the curse of negativity.

    Front. Neural. Circuits, January 5, 2021

    Vanwalleghem G., Constantin L., and E. Scott

  47. Social isolation uncovers a circuit underlying context-dependent territory-covering micturition

    Proc Natl Acad Sci U S A, January 5, 2021

    M Hyun, J Taranda, G Radeljic, L Miner, W Wang, N Ochandarena, et al.

  48. Capturing the complexity of topologically associating domains through multi-feature optimization

    bioRxiv 2021.01.04.425264, January 5, 2021

    N. Sauerwald and C. Kingsford

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