Search

What are you looking for?

  1. Prelimbic cortex drives discrimination of non-aversion via amygdala somatostatin interneurons

    Publication
    The amygdala and prelimbic cortex (PL) communicate during fear discrimination retrieval, but how they coordinate discrimination of a non-threatening stimulus is unknown. Here, we show that somatostatin …

  2. Partitioning variability in animal behavioral videos using semi-supervised variational autoencoders

    Publication
    ecent neuroscience studies demonstrate that a deeper understanding of brain function requires a deeper understanding of behavior. Detailed behavioral measurements are now often collected using video cameras, resulting …

  3. The Geometry of Abstraction in the Hippocampus and Prefrontal Cortex

    Publication
    The curse of dimensionality plagues models of reinforcement learning and decision making. The process of abstraction solves this by constructing variables describing features shared by different instances, reducing …

  4. Low-dimensional dynamics for working memory and time encoding

    Publication
    Our decisions often depend on multiple sensory experiences separated by time delays. The brain can remember these experiences and, simultaneously, estimate the timing between events. To understand the …

  5. The contribution of nonhuman primate research to the understanding of emotion and cognition and its clinical relevance.

    Publication
    Psychiatric disorders are often conceptualized as arising from dysfunctional interactions between neural systems mediating cognitive and emotional processes. Mechanistic insights into these interactions have been lacking in part …

  6. The coding of valence and identity in the mammalian taste system.

    Publication
    The ability of the taste system to identify a tastant (what it tastes like) enables animals to recognize and discriminate between the different basic taste qualities1,2. The …

  7. Basolateral amygdala circuitry in positive and negative valence.

    Publication
    All organisms must solve the same fundamental problem: they must acquire rewards and avoid danger in order to survive. A key challenge for the nervous system is therefore …

  8. Shared neural coding for social hierarchy and reward value in primate amygdala.

    Publication
    The social brain hypothesis posits that dedicated neural systems process social information. In support of this, neurophysiological data have shown that some brain regions are specialized for representing …

  9. Distinct Roles for the Amygdala and Orbitofrontal Cortex in Representing the Relative Amount of Expected Reward.

    Publication
    The same reward can possess different motivational meaning depending upon its magnitude relative to other rewards. To study the neurophysiological mechanisms mediating assignment of motivational meaning, we recorded …