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Biologists at the Simons Foundation’s Flatiron Institute and their colleagues strive to better understand remarkable living systems by bringing biology and mathematics into closer dialogue.

Flatiron Institute scientists and experimental collaborators tested a theory that treats chromosome-separating cellular structures called spindles as active liquid crystals. They found that the theory largely succeeds …

… continued conversation and eagerness to explore how their distinct practices might inspire and inform one another. The inaugural cohort of Open Interval consisted of a partnership between …

Through simulations and modeling of bacterial colonies, researchers at the Flatiron Institute and collaborators have discovered how dividing cells adapt to crowded environments by slowing their growth, informing …

CRISPR promises to be a game changer in the development of treatments for genetic diseases, but sometimes the technology slices DNA where it’s not supposed to. A …

New research led by Flatiron Institute researchers reveals the source of the mysterious swirling flows in some of nature’s largest cells.

A new facility at the Flatiron Institute’s Center for Computational Biology (CCB) bridges the gap between experimental and theoretical biology, allowing researchers to take big steps toward …

… New York University Courant Institute

By building a biophysical model that incorporates real-world biological complexity, scientists discover important links between the nanometer-sized motors that power a cell’s cilia and the …

The swirling currents occur when the rodlike structures that extend inward from the cells’ membranes bend together like wheat stalks caught in a strong breeze, report researchers at …

In new research, scientists take a biophysical approach to deciphering the cell’s mysteries.

A model system exploring ATP synthase reveals that rotation, repulsion and flow can crystallize proteins. It may explain a biophysical mystery in mitochondrial membranes.

Congestion causes the mass of tubes and motors that form chromosome-dividing spindles to move at full speed instead of slowing to a crawl, new research reveals.

Eleven researchers supported by the Simons Foundation are among the latest batch of prominent leaders in the arts and sciences, business, philanthropy and public affairs, elected as fellows …

… He holds a B.A. in mathematics from the University of Colorado, Boulder, and a Ph.D. in applied mathematics from the University of Arizona in Tucson …

Finding reveals the large-scale movement of genetic material through the nucleus of a working cell.

… convenience. Mike Shelley, Ph.D. Mike Shelley, New York University The interaction of a flowing fluid with immersed bodies — which may be compliant or active — defines a …