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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Light Matter School

    Workshop
    … Ruggenthaler & Markus Penz: Properties of the Pauli-Fierz Hamiltonian and Mathematical Details of Ab Initio Quantum Physics (Including Exercises) October 1, 2025 Simone Latini: Theoretical Perspective of …
  2. Ab Initio QEDFT School

    Workshop
    … condensed-matter physics. Leading experts at forefront of ab initio QED development will be in charge of the dissemination. The scope of this school is unique, it …
  3. Life on Earth Over Deep Time

    In Conversation
    … Her research studies past climate change with geochemistry and climate models. Studying past climates, including past warm climates and extreme events, can better inform how climate change …
  4. CCB Seminar: Viviana Risca, Ph.D.

    Seminar
    Viviana Risca, Ph.D., Rockefeller University Probing Sub-kilobase Chromatin Fiber Folding and its Regulation The kilobase-scale architecture of chromatin effectively defines the epigenomic landscape on which …
  5. 2025 Mathematical and Scientific Foundations of Deep Learning Annual Meeting

    Conference
    … Competing Mechanisms in Training Dynamics September 25, 2025 Nati Srebro | Weak to Strong Generalization in Random Feature Models September 26, 2025 Soledad Villar | Algebraic techniques for machine …
  6. GW Working Group

    Event
    Agenda Wednesday, September 25 Time Speaker 8:30 a.m. – 9:00 a.m. BREAKAST 9:00 a.m. – 9:30 a.m. WelcomeAntoine Georges 9:30 a …
  7. Where is Mathematics Going?

    Lecture
    Over the last 2,500 years, the way we do mathematics has changed surprisingly little. In Euclid’s Elements, we see lemmas, theorems and proofs, with material building …
  8. Computer Visionaries Interest Group Meeting

    Meeting
  9. At the Frontier of Light-Matter Interaction: Visions of Future Directions

    Workshop
    … AM Break 11:00 – 11:30 AM Lucia Reining (Ecole Polytechnique / CNRS) Excitons in absorption and loss spectroscopies: an old topic, new effects 11:30 AM – 12 …
  10. Structural & Molecular Biophysics Group Meeting

    Meeting
  11. Genomics Group Meeting

    Meeting
  12. Biophysical Modeling Group Meeting

    Meeting
  13. CCB Seminar: Joe Howard, Ph.D.

    Seminar
    Joe Howard, Ph.D., Yale University Branching Morphogenesis of Dendrites The highly elaborated branched morphologies of dendrites are responsible for the enormous diversity of neuronal cell types in …
  14. CCA Astrofest

    Meeting
  15. Developmental Dynamics Group Meeting

    Meeting
  16. CCA Colloquium: Matteo Cantiello

    Colloquium
    Title: Hard Problems in Computational Stellar Physics Abstract:  Despite remarkable observational progress, many fundamental aspects of stellar structure and evolution — particularly for the most massive stars — remain poorly …
  17. Google-CCQ HTS Mini Summit

    Meeting
  18. Flatiron Seminar Series: Jason Kaye

    Seminar
    Title: The Green’s function view of interacting quantum physics Abstract: The central challenge in simulating the physics of many interacting quantum particles is the exponential growth of …
  19. CCB Seminar: William Irvine, Ph.D.

    Seminar
    William Irvine, Ph.D., University of Chicago Quiet Within, Chaos Without: Harnessing Turbulence for Function Across Scales Turbulence is synonymous with chaos, yet its velocity fluctuations are structured …
  20. 2025 Simons Collaboration on Learning the Universe Annual Meeting

    Conference
    … modeling how interstellar dust alters galactic light, combining radiative transfer simulations with simplified prescriptions that balance realism and efficiency. We will also highlight recent work exploring the …
  21. Where Did All the Dogs Come From? Dogs, Ancestors, Breeds and Genomes

    Lecture
    The domestication of dogs is, arguably, the most successful scientific experiment in human history, resulting in millions of canids representing more than 350 recognized breeds along with feral …
  22. Genomics Group Meeting

    Meeting
  23. Computer Visionaries Interest Group Meeting

    Meeting
  24. Machine Learning at the Flatiron Institute: Anastasis Germanidis

    Seminar
    Title: Video Diffusion Models for Storytelling and World Modeling Abstract: I will discuss our work in training, deploying, and controlling image and video diffusion models for storytelling and …
  25. Structural & Molecular Biophysics Group Meeting

    Meeting
  26. Quantum Cafe: Subir Sachdev

    Colloquium
    Title: Fractionalized Femi Liquid (FL) Theory of the Cuprate Pseudogap, and its Connections to the Cuprate Phase Diagram Abstract: The pseudogap metal phase of the cuprate high-temperature …
  27. Biophysical Modeling Group Meeting

    Meeting
  28. Celebration for GW Decade

    Event
    September 15, 2025 Gravitational Wave Celebration
  29. Developmental Dynamics Group Meeting

    Meeting
  30. LtU Workshop 2025

    Event
  31. CCB Seminar: Antonio Costa, Ph.D.

    Seminar
    Antonio C. Costa | Paris Brain Institute, Sorbonne University  Comparing Dynamical Systems from Data: A Multiscale Approach Variability across realizations of dynamical systems is a hallmark of complexity, appearing …
  32. Emergent Phenomena Under Pressure: From Hydrogen to Hot Superconductors

    Lecture
    … the Percy W. Bridgman Award. He has co-authored approximately 700 scientific publications. His recent research at UIC has focused on the design, discovery and synthesis of …
  33. Computer Visionaries Interest Group Meeting

    Meeting
  34. Flat Bands: Frustration and Correlation Physics Workshop

    Workshop
    … Metals 5:00 – 6:30 PM Dinner Friday, September 12 8:00 – 9:00 AM Breakfast 9:00 – 9:50 AM Ronny Thomale (University of Wurzburg) Model …
  35. MPS Conference on Universal Statistics in Number Theory

    Conference
    … modules, and other algebraic structures that arise in arithmetic statistics. Ofer Zeitouni Weizmann Institute of Science Extrema of the Characteristic Polynomial of C𝛽E Matrices View Slides …
  36. Structural & Molecular Biophysics Group Meeting

    Meeting
  37. Genomics Group Meeting

    Meeting
  38. Biophysical Modeling Group Meeting

    Meeting
  39. Developmental Dynamics Group Meeting

    Meeting
  40. Workshop: Numerical Simulations of Super-Eddington Accretion Disks

    Workshop
  41. CCA Colloquium: Evan Kirby

    Colloquium
    Title: First Observations from the PFS Galactic Archaeology Survey Abstract: The Subaru Prime Focus Spectrograph is a new wide-field, massively multiplexed spectrograph at the prime focus of …
  42. Biological Transport Networks Group Meeting

    Meeting
  43. Table Top Experiments PI Meeting

    Conference
    … strontium atoms. We will show how such platforms enable the exploration of the interplay of quantum mechanics, gravitational effects, and photon-mediated interactions through first signatures of …
  44. Genomics Group Meeting

    Meeting
  45. Computer Visionaries Interest Group Meeting

    Meeting
  46. Structural & Molecular Biophysics Group Meeting

    Meeting
  47. Biophysical Modeling Group Meeting

    Meeting
  48. 2025 Flatiron Institute Seminar Series

    Seminar
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