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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Developmental Dynamics Group Meeting

    Meeting
  2. DMFT-QE Symposium: April 14, 2025

    Symposia
    … of the Anderson impurity model. The central idea is to use an SOE expansion of the hybridization function to separate variables, decomposing the multiple integrals into sequences …
  3. CCA Colloquium: Charles Gammie

    Colloquium
    Title: Black Hole Imaging: Past, Present, Future Abstract: Images of black holes, like those first provided by the Event Horizon Telescope, can reveal how black holes interact with …
  4. Structural & Molecular Biophysics Group Meeting

    Meeting
  5. Databases and Discovery in Arithmetic

    Lecture
    Arithmetic geometry is at the heart of pure mathematics, and modern computing power and algorithms are transforming the field. Massive parallel computations are now routinely used to construct …
  6. Machine Learning at the Flatiron Institute: Danqui Chen

    Lecture
    Title: Optimizing Data Use for Pre-training Language Models Abstract: Modern language models are trained on massive, unstructured data consisting of trillions of tokens, typically obtained by crawling …
  7. Developmental Dynamics Group Meeting

    Meeting
  8. 2025 National Institute for Theory and Mathematics in Biology Annual Meeting

    Conference
    … how competition in an ecosystem influences species’ abundances and a graph estimation problem using cell-signaling data from proteomics. In these settings, the proposed method yields stable …
  9. The Evolution of Darwin’s Finches

    Lecture
    Millions of species called Earth home. They evolved by repeated multiplication and diversification. To understand these processes, we have put the scientific spotlight on Darwin’s finches in …
  10. Genomics Group Meeting

    Meeting
  11. Machine Learning at the Flatiron Institute: Clément Hongler

    Seminar
    Title: Arrows of Time for Large Language Models Abstract: Large Language Models famously predict the next token in a text. What happens if we teach them to predict …
  12. Structural & Molecular Biophysics Group Meeting

    Meeting
  13. Quantum Café: Zoe Yan

    Colloquium
    Title: Local Probes of Correlated Matter in Atomic and Molecular Quantum Simulators Abstract: Exploring emergent behaviors in strongly interacting quantum systems is a frontier area. I will resent …
  14. Biophysical Modeling Group Meeting

    Meeting
  15. Developmental Dynamics Group Meeting

    Meeting
  16. Simons Society of Fellows Retreat 2025

    Conference
    … vlFPC and the temporo-parietal cortex, a predecessor to Wernicke’s area in humans. We observed that majority of MD neurons contribute to visual recognition and do …
  17. CCA Colloquium: Daniel Price

    Colloquium
    Title: Growing pains: the dining habits of stars, planets and black holes Abstract: To make planets, stars and supermassive black holes, one must rapidly accrete material onto central …
  18. Biomolecular Design Group Meeting

    Meeting
  19. 2025 Simons Collaboration on New Structures in Low-Dimensional Topology Annual Meeting

    Conference
    … these methods might be adapted towards addressing some of these questions. Lev Rozansky University of North Carolina Chapel Hill Quiver-Like Varieties for the Geometric Categorification of …
  20. Neutron Stars: The Supranuclear-Density Zombies of the Cosmos

    Lecture
    Our galaxy contains thousands of curious stars called neutron stars. Formed from the catastrophic collapse of massive stars, they are mind-blowingly compact, packing one to three solar …
  21. Structural & Molecular Biophysics Group Meeting

    Meeting
  22. Genomics Group Meeting

    Meeting
  23. Biophysical Modeling Group Meeting

    Meeting
  24. Developmental Dynamics Group Meeting

    Meeting
  25. CCA Colloquium: Joshua Speagle

    Colloquium
    … and data science to understand how galaxies like our own Milky Way form, behave, and evolve over time. He is also interested in broader problems within applied …
  26. CCB Seminar: Scott F. Gilbert, Ph.D.

    Seminar
    … co-author of the textbooks Developmental Biology (presently in its 13th edition), Ecological Developmental Biology (now in its second edition and being revised with David Pfennig), Evolution …
  27. 2025 Simons Collaboration on Hidden Symmetries and Fusion Energy Annual Meeting

    Conference
    … talk, we present a numerical algorithm that can evaluate the turnstile area directly from a stellarator coil solution, and which is efficiently calculated using an action principle …
  28. Evolution of the Cerebral Cortex: From New Types of Neurons to New Cognitive Functions

    Lecture
    Brains evolved to acquire all sorts of shapes, sizes and functions. Ultimately, their diversity is determined by the diversity of their building blocks: different types of neurons with …
  29. Genomics Group Meeting

    Meeting
  30. Structural & Molecular Biophysics Group Meeting

    Meeting
  31. Developmental Dynamics Group Meeting

    Meeting
  32. A Signal in the Noise

    In Conversation
    … School of Art.
  33. CCA Colloquium: Norman Murray

    Colloquium
    Title: Continuum Driven Active Galactic Nuclei Winds Abstract: It is often argued that accreting supermassive black holes can expel enough gas from their host galaxies to affect their …
  34. Machine Learning at the Flatiron Institute Seminar: Maximilian Nickel

    Seminar
    Title: Epistemic Limits of Model Validation in Complex Social Systems Abstract: AI has undergone a dramatic paradigm shift, not only in terms of the impressive capabilities of state …
  35. 2025 Simons Collaboration on Perfection in Algebra, Geometry and Topology Annual Meeting

    Conference
    … Sweeting | On the Bloch-Kato Conjecture for Some Four-Dimensional Symplectic Galois Representations March 14, 2025 Jacob Lurie | Prismatic Stable Homotopy Theory
  36. Verified Collaboration: How Lean is Transforming Mathematics, Programming, and AI

    Lecture
    Imagine a world where mathematicians, programmers and AI systems can collaborate with complete trust in each other’s work. This is the promise of Lean, an open-source …
  37. ACT DR6 Webinar

    Event
    March 18, 2025 Cosmological Results from Atacama Cosmology Telescope DR6
  38. Structural & Molecular Biophysics Group Meeting

    Meeting
  39. Genomics Group Meeting

    Meeting
  40. Biophysical Modeling Group Meeting

    Meeting
  41. Developmental Dynamics Group Meeting

    Meeting
  42. CCA Colloquium: Elisabeth Krause

    Colloquium
    Title: More Accurate Together: Opportunities in Multi-Survey Cosmology Abstract: Over the next decade, large galaxy surveys will map billions of galaxies and probe cosmic structure formation with …
  43. CCB Brown Bag Seminar

    Seminar
    SPEAKERS: Victor Chardès, Ph.D., Flatiron Research Fellow, Biophysical Modeling and Genomics  BIOPHYSICAL FLOW MODELS FOR SINGLE-CELL OMICS DATA:Single-cell omics methods such as single-cell …
  44. RNA-Guided Natural Genome Editing and the Emergence of Complex Genomes

    Lecture
    The ciliate Oxytricha is a single-celled eukaryote with multiple nuclei and two distinct nuclear genomes. In a feat of natural genome engineering, massive DNA rearrangements rebuild a …
  45. Structural & Molecular Biophysics Group Meeting

    Meeting
  46. Quantum Cafe: Premala Chandra

    Colloquium
    Title: Light-Induced Orderings that Oscillate in Space and in Time Abstract: The control and design of quantum materials are outstanding goals both to address fundamental questions and …
  47. Biophysical Modeling Group Meeting

    Meeting
  48. Genomics Group Meeting

    Meeting
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