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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Biomolecular Design Group Meeting

    Meeting
  2. The Earth’s Core: The Engine of Our Planet

    Lecture
    Three thousand kilometers beneath our feet lies a ball of churning liquid metal as thin as water and as hot as the sun’s surface: Earth’s outer …
  3. Machine Learning at the Flatiron Institute Seminar: Ziming Liu

    Seminar
    Title: Towards Unification of Artificial Intelligence and Science Abstract: A major challenge of AI + Science lies in their inherent incompatibility: today’s AI is primarily based on connectionism …
  4. Structural and Molecular Biophysics Group Meeting

    Meeting
  5. Genomics Group Meeting

    Meeting
  6. Biophysical Modeling Group Meeting

    Meeting
  7. Developmental Dynamics Group Meeting

    Meeting
  8. SFARI Sex Differences Collaboration

    Annual Meeting 2025
    Overview On January 27–28, 2025, Simon Foundation Executive Vice President of Autism and Neuroscience Kelsey Martin and SFARI Senior Scientist Alan Packer opened the annual meeting of …
  9. Autism Rat Models Consortium 2.0 RFA: Informational Session

    Webinar
    On January 23, 2025, SFARI held an informational session about the Autism Rat Models Consortium 2.0 RFA.
  10. CCB Colloquium: Martin H. Wühr, Ph.D.

    Colloquium
    Speaker: Martin H. Wühr, Ph.D. (Princeton University)  Title: Proteomic Clues to Cell Organization Abstract: Quantitative proteomics has emerged as a powerful tool for investigating cellular organization at …
  11. 2025 Simons Collaboration on Ultra Quantum Matter Annual Meeting

    Conference
    … Bose Systems January 24, 2025 Nathan Seiberg | Anomalous Continuous Translations January 24, 2025 Monika Schleier-Smith | Atoms Interlinked by Light: Programmable Nonlocal Interactions for Quantum Simulation January …
  12. Perturbations and Climate Change Shape Dynamics of Neurons and Circuits

    Lecture
    A fundamental problem in neuroscience is understanding how the properties of individual neurons and synapses contribute to neuronal circuit dynamics and behavior. Computational and experimental studies demonstrate that …
  13. CCB Seminar: Vitor Leite, Ph.D.

    Seminar
    Speaker: Vitor Leite, Ph.D. (São Paulo University)  Title: From Multidimensional Challenges to Intuitive Insights in Biomolecular Landscapes  Abstract: Understanding the dynamic behavior of biomolecules involves navigating vast …
  14. Genomics Group Meeting

    Meeting
  15. Structural and Molecular Biophysics Group Meeting

    Meeting
  16. Flatiron Seminar Series: Christopher Park

    Seminar
    Title: Unraveling Hormonal Regulation and Its Influence on Human Health and Disease Abstract: Understanding the role of hormonal regulation in human health and disease presents significant challenges. In …
  17. CCB Brown Bag Seminar

    Seminar
    1st presenter:  Gilles Francfort, Ph.D., Research Scientist Topic: Liquid filled elastomers Abstract: Expounding the observations made by Dufresne (Yale University) and collaborators in 2016, we demonstrate in …
  18. Biomolecular Design Group Meeting

    Meeting
  19. Electron Microscopy Interest Group (EMIG) Seminar: Richard Hite, Ph.D.

    Seminar
    Speaker: Richard Hite, Ph.D. (Memorial Sloan Kettering Cancer Center) Talk Title: Cryo-EM structures of G4-stalled CMG reveal inchworm mechanism of DNA translocation Abstract: DNA G …
  20. 2025 Simons Collaboration on Arithmetic Geometry, Number Theory, and Computation Annual Meeting

    Conference
    … Multiplication Let (K) be an imaginary quadratic field, and let (mathcal{O}_{K,f}) be an order in (K) of conductor (f geq 1). Let (E) be …
  21. Structural and Molecular Biophysics Group Meeting

    Meeting
  22. Genomics Group Meeting

    Meeting
  23. Biophysical Modeling Group Meeting

    Meeting
  24. Developmental Dynamics Group Meeting

    Meeting
  25. DMFT-QE Symposium: January 13, 2025

    Symposia
    … Bilayer Graphene: Correlated Gaps and Pairing January 13, 2025 Roser Valenti: Heavy Fermions vs. Doped Mott Physics in Heterogeneous Ta-Dichalcogenides Bilayers
  26. Developmental Dynamics Group Meeting

    Meeting
  27. ML@FI Seminar Series

    Seminar
  28. CCB Seminar: Sheng Chen, Ph.D. (Yale University)

    Seminar
  29. Computer Vision Interest Group Meeting

    Meeting
  30. Genomics Group Meeting

    Meeting
  31. Biophysical Modeling Group Meeting

    Meeting
  32. Structural & Molecular Biophysics Group Meeting

    Meeting
  33. Developmental Dynamics Group Meeting

    Meeting
  34. DMFT-QE Symposium: December 16, 2024

    Symposia
    … 16, 2024 Yuka Murakami – Numerical Exploration of High-Harmonic Generation in Strongly Correlated Systems December 16, 2024 Hebert F. Fotso – Disorder in the nonequilibrium dynamics of a …
  35. CCB Colloquium: Olga Dudko, Ph.D. (University of California San Diego)

    Colloquium
  36. Genomics Group Meeting

    Meeting
  37. Molecular Dynamics

    Short Course
    This course, co-taught by Sonya Hanson, Chris Edelmaier, Miro Astore, and Abhilash Sahoo, will explore computational methods for modeling the properties of complex systems based on the …
  38. Conference Support for Rare Neurodevelopmental Disorder Communities Participating in Simons Searchlight: Informational Session

    Webinar
    On December 11, 2024, SFARI held an informational session about the Conference Support for Rare Neurodevelopmental Disorder Communities Participating in Simons Searchlight.
  39. Computer Vision Interest Group Meeting

    Meeting
  40. Biophysical Modeling Group Meeting

    Meeting
  41. Structural & Molecular Biophysics Group Meeting

    Meeting
  42. Developmental Dynamics Group Meeting

    Meeting
  43. Cosmology and galaxy astrophysics with simulations and machine learning 2024

    Conference
    … Pandya, Nicholas Frontiere, Jeger Cornelis Broxterman, Megan Tillman December 12, 2024 Cosmology and Galaxy Astrophysics with Simulations and Machine Learning | Day 4 Session 2: Chun-Hao To …
  44. Relationships: Same, Same but Different

    In Conversation
    … Developmental Dynamics group. Jasmin completed her doctorate work at Princeton University before joining MIT’s Department of Biology as a postdoc. Before that, she received her B …
  45. CCB Brown Bag Seminar

    Meeting
  46. 2024 Simons Collaboration on Wave Turbulence Annual Meeting

    Annual Meeting
    … as long as the solution to this kinetic equation exists. This represents a crucial step toward resolving the Hilbert sixth problem. December 5, 2024 Vincenzo Vitelli | Odd …
  47. Collision Course: Particle Physics Meets Machine Learning

    Lecture
    Modern machine learning has had an outsized impact on many scientific fields, and particle physics is no exception. What is special about particle physics, though, is the vast …
  48. Molecular Dynamics

    Short Course
    This course, co-taught by Sonya Hanson, Chris Edelmaier, Miro Astore, and Abhilash Sahoo, will explore computational methods for modeling the properties of complex systems based on the …
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