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So-called “collective behavior” surrounds us.

Imagine catching a firefly.

The brain is composed of networks of thousands or millions of neurons, and modern neuroscience is just reaching the stage where researchers can observe most, if not all …

How do complex patterns of activity in large populations of neurons gain meaning and guide behavior?

Analyzing a complex motor act at the mesoscopic scale Michael Long, New York University Liam Paninski, Columbia University   Attentional modulation of neuronal variability constrains circuit models Marlene Cohen …

To understand the neurobiology behind autism, we need data at the cellular level.

Benjamin Cheyette and his colleagues at the University of California, San Francisco have discovered several variations in the sequence of the DIXDC1 gene in individuals with autism, using …

Understanding how genetic defects that cause autism lead to abnormal neurodevelopment is critical to developing mechanism-based treatments.

Autism appears to be caused by a complex interplay of genetic and environmental factors.

Understanding the emotional state of a person one is communicating with stands at the center of meaningful and successful human interaction, and speech serves as a conduit for …

The proposed research takes advantage of the resources available at the University of Oxford in the U.K.

Autism is diagnosed in boys four times more frequently than in girls.

A core symptom of autism involves impaired social relationships.

Genetics is important in the etiology of autism, with many identified candidate genes linking autism to synaptic pathology.

The development of safe and effective new treatments for social impairments in autism is an important priority.

Illness or infections during early pregnancy are associated with increased incidence of autism.

Immune‐related genes and immune responses to environmental stimuli are receiving attention due to their potential involvement in several neurodevelopmental disorders, including autism.

Brian J.

Anatomic and molecular features observed in the brains of individuals with autism suggest that abnormalities in early embryonic development underlie the development of autism.

Mutations in hundreds of genes may predispose individuals to autism, but no common feature characterizes these genes, little is known about the functions of many of them and …

Nearly 90 percent of children with autism are estimated to suffer from sensory abnormalities, often hypersensitivities, to stimuli that a neurotypical individual could ignore.

Biological networks provide a natural framework for integrating the diverse genetic variations associated with complex and multifactorial disorders.

We are beginning to identify many genetic alterations, environmental factors and developmental processes that contribute to autism, but we do not yet understand how various molecular perturbations add …

Children with the rare genetic disorder Prader-Willi syndrome have a high rate of autism spectrum disorders, with features including restricted and repetitive, compulsive and self-injurious behaviors.

Fragile X syndrome is the most common cause of inherited autism and results from loss of function of a single gene: FMR1.

Efforts to find genetic causes of autism have identified hundreds of rare mutations in individuals with the disorder, and this list is anticipated to grow steadily in the …

There is growing support for the idea that both genetic and environmental risk factors contribute to autism.

A major goal of autism research is to understand the relationships among genetic etiology, altered developmental trajectory, aberrant neural circuits and behavioral symptoms characteristic of this disorder.

Finding a way to diagnose autism early in development is crucial for devising new interventions and understanding its underlying neurobiological causes.

Evan Eichler and his colleagues at the University of Washington aim to perform the systematic discovery of single nucleotide variations (SNVs), insertions and deletions in DNA (indels) and …

Autism is a complex disorder of many biological causes that results in characteristic behavioral symptoms.

A large number of susceptibility genes for autism and schizophrenia have been identified, although the function of many of these risk factors in regulating neuronal development is not …

The etiology of autism is complex and mysterious.

Human brain function is the result of a highly organized network of connections linking multiple areas across the brain.

A rapidly increasing number of genes are implicated in autism.

Nerve cells communicate with each other via excitatory and inhibitory signals.

Studies have identified a large number of genes that contribute to autism, and many affect communication between neurons, known as synaptic transmission.

Autism is characterized by profound social impairments.

Autism is most likely caused by changes in the development of the cerebral cortex, particularly in neural circuits that process social and cognitive information.

Comprehensive studies of the human genome using high-speed DNA sequencing have identified new genes whose mutations appear to contribute to autism.

Individuals with autism frequently display accelerated brain growth during infancy and a larger brain size that is also associated with increased symptom severity.

A small protein called ubiquitin is added to other proteins to modify their function, causing changes in cellular behavior.

Our species’ remarkable cognitive, perceptive and motor capabilities depend on the formation, maturation and maintenance of neuronal connectivity in the brain. Miswiring or dysfunction of neural circuits can …

Advances in structural magnetic resonance imaging (MRI) offer improved ability to detect subtle abnormalities in brain architecture.

Over the past few years, studies have linked many genes to autism.

Recent discoveries of contrasting phenotypes caused by deletion vs.