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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Simons Observatory Meeting

    Meeting
  2. Simulating the Quantum World with Data-Free, Physics-Driven Machine Learning

    Lecture
    The behavior of electrons is chiefly responsible for the properties of materials and molecules. Predicting the behavior of many interacting electrons poses a significant scientific challenge and has …
  3. Genomics Group Meeting

    Meeting
  4. Molecular Dynamics

    Short Course
    This course, co-taught by Sonya Hanson, Chris Edelmaier, Miro Astore, and Abhilash Sahoo, will explore computational methods for modeling the properties of complex systems based on the …
  5. Computer Vision Interest Group Meeting

    Meeting
  6. Machine Learning at the Flatiron Institute Seminar: Andrea Liu

    Seminar
    Title: Overparameterization is everywhere Abstract: Neural networks can learn complex tasks easily when they are overparameterized, with the number of parameters that describe interactions between neurons dwarfing the …
  7. Structural & Molecular Biophysics Group Meeting

    Meeting
  8. Biophysical Modeling Group Meeting

    Meeting
  9. Developmental Dynamics Group Meeting

    Meeting
  10. Imagining Other Worlds

    In Conversation
    … of Chicago. Ari Melenciano has cultivated an expansive practice within the arts, technology, design, culture and pedagogy. Her natural ability to combine many disciplines reveals their interconnectedness …
  11. CCA Colloquium: Anthony Mezzacappa

    Colloquium
    October 25, 2024 Anthony Mezzacappa – The Era of Precision Core Collapse Supernova Modeling
  12. CCA Colloquium: Tony Mezzacappa

    Colloquium
    CCA Colloquium takes place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  13. 2024 Simons Collaboration on Extreme Wave Phenomena Based on Symmetries Annual Meeting

    Conference
    … symmetry class and stability properties of “nonlinear ground states.” While for continuum problems, there is much known about the symmetry class of optimizers, much less is understood …
  14. The Geometry of Multicellular Life

    Lecture
    3 One of the most fundamental issues in evolutionary biology is how unicellular life transitioned to multicellular life. How — and why — was it that the simplest single-celled …
  15. 2024 Flatiron Wide Autumn Meeting

    Conference
    FWAM (“Flatiron-wide Autumn Meeting”, previously “Flatiron-wide Algorithms and Mathematics”) is a two-day internal conference with the goal of introducing and reviewing scientific and computational tools …
  16. Biophysical Modeling Group Meeting

    Meeting
  17. Developmental Dynamics Group Meeting

    Meeting
  18. DMFT-QE Symposium: October 21

    Symposia
    … conceptually simple tool for effectively describing dissipation. Recently, investigating the topological properties of such NH systems has become a broad frontier of research. In this talk, I …
  19. CCA Colloquium: Dylan Nelson

    Colloquium
    CCA Colloquium takes place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  20. Flatiron Institute Seminar Series: Scott Weady

    Lecture
    Title: From micro to macroscopic models of living matter Abstract: Living systems typically consist of a large number of active, interacting constituents. Whether mediated through fluid flows, chemical …
  21. 2024 MPS Annual Meeting

    Conference
    … work with my collaborator Mihaela Ifrim from University of Wisconsin, Madison. Tataru’s work on nonlinear waves has been deep and influential. He proved difficult well-posedness …
  22. Copernicus Revisited: Is Earth Special?

    Lecture
    Nearly 500 years ago, Nicolaus Copernicus published his disruptive theory that Earth is not the center of the universe. This ‘Copernican demotion’ has held fast over the centuries …
  23. Machine Learning at the Flatiron Institute Seminar: Siamak Ravanbaksh

    Seminar
    Title: Symmetry, Beyond Invariant Networks Abstract: Invariant and equivariant networks have been the primary mechanism for imbuing machine learning with symmetry awareness. However, constraining architectures with symmetry may …
  24. Quantum Cafe: Long Ju

    Colloquium
    Title: Emergent Phenomena in Crystalline Graphene Abstract: Condensed matter physics has witnessed many emergent quantum phenomena driven by electron correlation and topology. Such phenomena have been mostly observed …
  25. JAXtronomy

    Event
  26. EPRV Pipelines Meeting

    Meeting
  27. AstroFest/FRF Orientation

    Event
  28. Social Cognition, Autism and the Human Brain

    Lecture
    We regularly infer the mental states and traits of others simply by watching them, an ability that may distinguish our cognition from that of other animals. This ability …
  29. Machine Learning at the Flatiron Institute Seminar: Aditi Krishnapriyan

    Seminar
    Title: The role of scaling and training strategies in machine learning for scientific modeling Abstract: Machine learning in the scientific domain has made rapid progress in recent years …
  30. Simons Foundation Autism and Neuroscience SfN Social

    Social
    The Simons Foundation welcomed all SfN 2024 attendees for an evening of socializing and updates. Scientific staff from the Simons Foundation’s grantmaking initiatives in autism (SFARI), and …
  31. Simons Foundation Autism and Neuroscience SfN Social

    SCPAB
    All Society for Neuroscience annual meeting attendees are welcome to join Simons Investigators and scientific staff from the Simons Foundation Autism Research Initiative (SFARI), Smons Collaboration on the …
  32. CCA Colloquium: Phil Hopkins

    Colloquium
    CCA Colloquium takes place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  33. Quantum Cafe: Ana Marie Rey

    Colloquium
    Title: Observation of itinerant magnetism in polar molecule confined in optical lattices Abstract: Photon mediated interactions in polar molecules give rise to strong long-range and anisotropic dipolar …
  34. CCA Colloquium: Keri Hoadley

    Colloquium
    CCA Colloquium takes place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  35. 2024 Mathematical and Scientific Foundations of Deep Learning Annual Meeting

    Conference
    … hard? September 27, 2024 Jingfeng Wu | Reimaging Gradient Descent: Large Stepsize, Oscillation, and Acceleration September 27, 2024 Gitta Kutyniok | Reliable AI: From mathematical foundations to next generation …
  36. (Machine) Learning the Genealogy of the Milky Way

    Lecture
    Galaxies form and grow by merging with other galaxies, making the formation history of a galaxy resemble that of a family tree. Our galaxy, the Milky Way, is …
  37. Machine Learning at the Flatiron Institute Seminar: Grace Lindsay

    Seminar
    Title: Analyzing artificial neural networks to understand the brain Abstract: In the first part of this talk, I will present work showing that artificial neural networks with recurrent …
  38. CCA Colloquium: Neal Weiner

    Colloquium
    CCA Colloquium takes place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  39. High Temperature Superconductivity (HTS) Workshop

    Conference
    Workshop exploring the use of machine learning methods to construct an expert system that can answer questions about high transition temperature superconductor  based on an efficient compilation of …
  40. 2024 Simons Collaboration on Learning the Universe Annual Meeting

    Conference
    … suite of statistical methods to ensure the accuracy of our trained emulators that can assess the quality of the distribution of the produced simulations compared to traditional …
  41. 2024 Simons Society of Fellows Alumni Symposium

    Conference
    … rather a range of human natures. This talk examines the core scientific evidence for human natures and places it in dialogue with contemporary issues facing humanity. Subhadra …
  42. Quantum Cafe: Rafael Fernandes

    Colloquium
    … different symmetries of the system, such as superconductivity, magnetism, nematic ordering, and orbital September 17, 2024 Rafael Fernandes: Topological Properties of Altermagnets
  43. DMFT-QE Symposium: September 16

    Symposia
    … optical properties. [1] Galler and Pourovskii, New J. Phys. 24, 043039 (2022) [2] Galler, Boust, Demourgues, Biermann and Pourovskii, PRB 103, L241105 (2021) For the full DMFT …
  44. LtU Workshop 2024

    Event
  45. CCA Colloquium: Janice Lee

    Colloquium
    CCA Colloquium takes place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  46. MPS Workshop on Perspectives on Electronic Information & Communication in the Mathematical Sciences

    Workshop
    … Predatory Publishers 10:00 AM Kevin Buzzard | The impact of AI & Computer Proof Assistants on Mathematical Publishing 11:00 AM Breakout Discussion Sessions 3 & 4 1:00 …
  47. Deciphering the Genomic Rosetta Stone

    Lecture
    Sequencing the genomic material of living organisms can be likened to using telescopes to peer into the universe’s past. By studying genetics, we can glean information about …
  48. Amplitudes Meet Cosmology (2024)

    Symposia
    … 12:30 PM Dionysios Anninos | State of Holographic Cosmology 5:00 – 6:00 PM Jaroslav Trnka | Positivity View Slides (PDF) 6:15 – 7:15 PM Henrik Johansson …
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