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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
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  • Newsletter Sign Up
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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Genomics Group Meeting

    Meeting
  2. Biophysical Modeling Group Meeting

    Meeting
  3. Developmental Dynamics Group Meeting

    Meeting
  4. CCA Colloquium: Zhaohuan Zhu

    Colloquium
    CCA Colloquium stake place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  5. 2024 National Institute for Theory and Mathematics in Biology Annual Meeting

    Conference
    … for model selection of biological metabolic and regulatory networks. Arvind Murugan University of Chicago The Origin of Non-Equilibrium Order View Slides (PDF) Since at least Schrödinger …
  6. The Next Great Scientific Theory is Hiding Inside a Neural Network

    Lecture
    Machine learning methods such as neural networks are quickly finding uses in everything from text generation to construction cranes. Excitingly, those same tools also promise a new paradigm …
  7. Genomics Group Meeting

    Meeting
  8. Machine Learning at the Flatiron Institute Seminar: Soledad Villar

    Seminar
    Title: Exact and approximate symmetries in machine learning Abstract: In this talk, we explain how we can use invariant theory tools to express machine learning models that preserve …
  9. Structural & Molecular Biophysics Group Meeting

    Meeting
  10. Biophysical Modeling Group Meeting

    Meeting
  11. CCA Colloquium Schedule

    Colloquium
    Select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room from 4:00pm – 5:30pm
  12. Developmental Dynamics Group Meeting

    Meeting
  13. 2024 Simons Collaboration on New Structures in Low-Dimensional Topology Annual Meeting

    Conference
    … planar graphs Mrunmay Jagadale Caltech BPS cohomology for three Manifolds with Knots Isabella Khan Princeton University Bimodules in bordered Heegaard Floer homology Qianhe Qin Stanford University Discovering …
  14. The Story of the First Two Hours of a Fly's Life

    Lecture
    The fruit fly Drosophila melanogaster is a classical model organism of embryonic development. The mechanisms that lead to an adult, fully-developed animal from an unstructured embryo are …
  15. Structural & Molecular Biophysics Group Meeting

    Meeting
  16. Genomics Group Meeting

    Meeting
  17. Biophysical Modeling Group Meeting

    Meeting
  18. Developmental Dynamics Group Meeting

    Meeting
  19. Totality

    In Conversation
    … focuses on novel statistical and machine learning tools to address cosmic mysteries like the origins and fate of the universe. Baron is the author of “American Eclipse …
  20. CCA Colloquium: Emma Beasor

    Colloquium
    CCA Colloquium stake place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  21. Flatiron Institute Seminar Series: Natalie Sauerwald

    Seminar
    Title: Insights from a longitudinal SARS-CoV-2 multi-omic study Abstract: Since early 2020, SARS-CoV-2 has drastically changed the world around us and raised seemingly …
  22. 2024 Simons Collaboration on Hidden Symmetries and Fusion Energy Annual Meeting

    Conference
    … Average: an Efficient Test for Chaos March 21, 2024 David Pfefferlé | The Fine Print of The Magneto – Hydrostatistics Problem March 21, 2024 Carl Sovinec | Spectral-Element Magnetohydrodynamics …
  23. The Climate Multiscale Challenge From the Lens of the Ocean

    Lecture
    The grand challenge posed by climate change is rooted in the climate system’s multiscale character and high dimensionality. In other words, solving climate change involves accounting for …
  24. Genomics Group Meeting

    Meeting
  25. Structural & Molecular Biophysics Group Meeting

    Meeting
  26. Quantum Café: Xiaodong Xu

    Colloquium
    Title: Observation of Fractional Quantum Anomalous Hall Effect Abstract: The interplay between spontaneous symmetry breaking and topology can result in exotic quantum states of matter. A celebrated example …
  27. Biophysical Modeling Group Meeting

    Meeting
  28. Developmental Dynamics Group Meeting

    Meeting
  29. Simons Society of Fellows Retreat 2024

    Conference
    … of the mirror-asymmetric universe constructed from catalogs of galaxies measured by large telescopes, commenting both on the plausibility of these findings and their implications for our …
  30. Face to Face: The Special Ways of Our Social Minds and Brains

    Lecture
    Humans and all primates are social. Our primate sociality is a special one: it centers around the face as an active interface of social communication and connects to …
  31. Structural & Molecular Biophysics Group Meeting

    Meeting
  32. Genomics Group Meeting

    Meeting
  33. Biophysical Modeling Group Meeting

    Meeting
  34. Developmental Dynamics Group Meeting

    Meeting
  35. DMFT-QE Symposium: March 11

    Symposia
    … around 100K, (ii) the ordering of these local isospin moments at around 10K, and (iii) a cascadic redistribution of charge between localized and delocalized electronic states upon …
  36. Stable Mass Transfer in Binaries: from onset to remnants

    Conference
    … Disks During Stable Mass Transfer March 11, 2024 David Hendriks: Asynchronous Mass-Transfer March 11, 2024 Hugues Sana and Silvia Toonen: Plenary Discussion March 12, 2024 Pablo …
  37. CCA Colloquium: Alexandra Amon

    Colloquium
    CCA Colloquium stake place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  38. 2024 Simons Collaboration on Perfection in Algebra, Geometry and Topology Annual Meeting

    Conference
    … [email protected] (212) 524-6080 March 7, 2024 Bhargav Bhatt | The p-adic Simpson Correspondence March 7, 2024 Juan Esteban Rodríguez Camargo | p-adic D-modules …
  39. Genomics Group Meeting

    Meeting
  40. Exploring and Exploiting the Biomolecular Structure and Function with Machine Learning: Biodiversity and Beyond

    Lecture
    … biomolecular structure as a member of the Rosetta project. At Genentech Research and Early Development (gRED), Bonneau and his team build new methods for applying machine learning …
  41. Machine Learning at the Flatiron Institute Seminar: Sam Rodrigues

    Seminar
    Title: Automating Research at FutureHouse Abstract: In this talk, I will discuss our work at FutureHouse, a new, philanthropically-funded research lab in San Francisco focused on automating …
  42. Structural & Molecular Biophysics Group Meeting

    Meeting
  43. Biophysical Modeling Group Meeting

    Meeting
  44. Developmental Dynamics Group Meeting

    Meeting
  45. COSYNE 2024 Workshop: I Can't Believe It's Not Better!

    Workshop
    For more information visit the COSYNE website. March 4, 2024 John Pearson: What Ever Happened to Deep Bayesian Inference? March 4, 2024 Nathan Close: Differentiable Optimization of Similarity …
  46. CCA Colloquium Schedule

    Colloquium
    Select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room from 4:00pm – 5:30pm
  47. CCA Colloquium: Maya Fishbach

    Colloquium
    CCA Colloquium stake place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room …
  48. XMC Workshop

    Workshop
    … globular clusters SOC: Danny Horta, David Nidever, Adrian Price-Whelan, Mary Putman, Nitya Kallivayalil, Kate Daniel, and Nico Garavito-Camargo LOC: Danny Horta and Nico Garavito-Camargo
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