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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Generalized Compressed Sensing for Image Reconstruction with Diffusion Probabilistic Models

    Publication
    We examine the problem of selecting a small set of linear measurements for reconstructing high-dimensional signals. Well-established methods for optimizing such measurements include principal component analysis …
  2. The first complete 3D reconstruction and morphofunctional mapping of an insect eye

    Publication
    The structure of compound eyes in arthropods has been the subject of many studies, revealing important biological principles. Until recently, these studies were constrained by the two-dimensional …
  3. Quantifying neurobehavioral profiles across neurodevelopmental genetic syndromes and idiopathic neurodevelopmental disorders.

    Publication
  4. Heuristic energy-based cyclic peptide design

    Publication
    Rational computational design is crucial to the pursuit of novel drugs and therapeutic agents. Meso-scale cyclic peptides, which consist of 7-40 amino acid residues, are of …
  5. The Geometry of Prompting: Unveiling Distinct Mechanisms of Task Adaptation in Language Models

    Publication
    Decoder-only language models have the ability to dynamically switch between various computational tasks based on input prompts. Despite many successful applications of prompting, there is very limited …
  6. Expanding Ejecta Method: I. Mapping Supernova Morphology with Intensity Interferometry

    Publication
    We explore the potential of optical intensity interferometry to extract angularly resolved information from supernova explosions, introducing the "expanding ejecta method" (EEM) as a robust alternative to the …
  7. Euclid preparation: TBD. Cosmic Dawn Survey: evolution of the galaxy stellar mass function across 0.2degrees

    Publication
    The Cosmic Dawn Survey Pre-launch (PL) catalogues cover an effective 10.13 deg\(^{2}\) area with uniform deep Spitzer/IRAC data (\(m\sim25\) mag, 5\(\sigma\)), the …
  8. Distributional Associations vs In-Context Reasoning: A Study of Feed-forward and Attention Layers

    Publication
    Large language models have been successful at tasks involving basic forms of in-context reasoning, such as generating coherent language, as well as storing vast amounts of knowledge …
  9. \(\Sigma\)-Attention: A Transformer-based operator learning framework for self-energy in strongly correlated systems

    Publication
    We introduce Σ-Attention, a Transformer-based operator-learning framework to address a key computational challenge in correlated materials. Our approach utilizes an Encoder-Only Transformer as an …
  10. Superfast Direct Inversion of the Nonuniform Discrete Fourier Transform via Hierarchically Semiseparable Least Squares

    Publication
    A direct solver is introduced for solving overdetermined linear systems involving nonuniform discrete Fourier transform matrices. Such matrices can be transformed into a Cauchy-like form that has …
  11. Theory of Coulomb driven nematicity in a multi-valley two-dimensional electron gas

    Publication
    The properties of a two-dimensional electron gas (2DEG) in a semiconductor host with two valleys related by an underlying \(C_4\) rotational symmetry are studied using Hartree …
  12. Mapping the landscape of social behavior.

    Publication
  13. Search for Axions in Magnetic White Dwarf Polarization at Lick and Keck Observatories

    Publication
    We present the most sensitive search to date for light axion-like particles with masses below a micro-eV, using spectropolarimetric data collected from the Lick and Keck …
  14. Control-driven critical fluctuations across quantum trajectories

    Publication
    Monitored quantum circuits in which entangling unitary dynamics compete with projective local measurements can host measurement-induced phase transitions witnessed by entanglement measures at late times. Adding feedback …
  15. Charge distribution and helicity tune the binding of septin's amphipathic helix domain to membranes

    Publication
    Amphipathic helices (AHs) are secondary structures that can facilitate binding of proteins to the membrane by folding into a helix with hydrophobic and hydrophilic faces that interact with …
  16. Charge distribution and helicity tune the binding of septin's amphipathic helix domain to membranes

    Publication
    Amphipathic helices (AHs) are secondary structures that can facilitate binding of proteins to the membrane by folding into a helix with hydrophobic and hydrophilic faces that interact with …
  17. Perceptual learning improves discrimination but does not reduce distortions in appearance

    Publication
    Human perceptual sensitivity often improves with training, a phenomenon known as “perceptual learning.” Another important perceptual dimension is appearance, the subjective sense of stimulus magnitude. Are training-induced …
  18. Formation of Drosophila germ cells requires spatial patterning of phospholipids

    Publication
    Germline-soma segregation is crucial for fertility. Primordial germ cells (PGCs) arise early in development and are the very first cells to form in the Drosophila embryo. At …
  19. Observing Spatial Charge and Spin Correlations in a Strongly-Interacting Fermi Gas

    Publication
    In this work, we explore two-dimensional attractive Fermi gases at the microscopic level by probing spatial charge and spin correlations in situ. Using atom-resolved continuum quantum …
  20. Higher-order Mean-motion Resonances Can Form in Type I Disk Migration

    Publication
    Type-I disk migration can form a chain of planets engaged in first-order mean-motion resonances (MMRs) parked at the disk inner edge. However, while second- or …
  21. Fast Transients from Magnetic Disks around Nonspinning Collapsar Black Holes

    Publication
    Most black holes (BHs) formed in collapsing stars have low spin, though some are expected to acquire a magnetic accretion disk during the collapse. While such BH disks …
  22. The Cosmic Evolution Early Release Science Survey (CEERS)

    Publication
    We present the Cosmic Evolution Early Release Science (CEERS) Survey, a 77.2 hr Director's Discretionary Early Release Science Program. CEERS demonstrates, tests, and validates efficient extragalactic …
  23. TOI-6324 b: An Earth-mass Ultra-short-period Planet Transiting a Nearby M Dwarf

    Publication
    We report the confirmation of TOI-6324 b, an Earth-sized (1.059 ± 0.041 R\(_{\oplus}\)) ultra-short-period (USP) planet orbiting a nearby (∼20 pc) M …
  24. The 4–400 GHz Survey for the 32 Class II Disks in the Taurus Molecular Cloud

    Publication
    We have compiled the ∼4–400 GHz broad spectra of 32 Class II protoplanetary disks (PPDs) in the Taurus-Auriga region, which represents the brightest one-third of …
  25. An Equilibrium Model of the Galaxy Determined by Element Abundance Gradients

    Publication
    We present a method to determine the gravitational potential of the Milky Way from measurements of the locations, velocities, and element abundances of stars in the Galactic disk …
  26. Cosmological Simulations of Stellar Halos with Gaia Sausage–Enceladus Analogs: Two Sausages, One Bun?

    Publication
    Observations of the Milky Way's stellar halo find that it is predominantly comprised of a radially biased population of stars, dubbed the Gaia Sausage–Enceladus, or GSE …
  27. Subphotospheric Emission from Short Gamma-Ray Bursts. II. Signatures of Nonthermal Dissipation in the Multi-messenger Signals

    Publication
    Building on a general relativistic magnetohydrodynamic simulation of a short gamma-ray burst (sGRB) jet with initial magnetization σ\(_{0}\) = 150, propagating through the dynamical ejecta from a …
  28. The BoRG-JWST Survey: Program Overview and First Confirmations of Luminous Reionization-era Galaxies from Pure-parallel Observations

    Publication
    We present the BoRG-JWST survey, a combination of two JWST Cycle 1 programs aimed at obtaining NIRSpec spectroscopy of representative, UV-bright 7 < z < 10 galaxy candidates …
  29. Cosmological Predictions for Minor Axis Stellar Density Profiles in the Inner Regions of Milky Way–mass Galaxies

    Publication
    ΛCDM cosmology predicts the hierarchical formation of galaxies, which build up mass by merger events and accreting smaller systems. The stellar halo of the Milky Way (MW) has …
  30. StreamSculptor: Hamiltonian Perturbation Theory for Stellar Streams in Flexible Potentials with Differentiable Simulations

    Publication
    Stellar streams are one of the most promising tracers of low-mass dark-matter subhalos. Existing frameworks for modeling stream perturbations rely on restrictive assumptions for the Milky …
  31. Introducing the DREAMS Project: DaRk mattEr and Astrophysics with Machine Learning and Simulations

    Publication
    We introduce the DaRk mattEr and Astrophysics with Machine learning and Simulations (DREAMS) project, an innovative approach to understanding the astrophysical implications of alternative dark matter (DM) models …
  32. A 100 Mpc\(^2\) structure traced by hyperluminous galaxies around a massive \(z\) = 2.85 protocluster

    Publication
    We present wide-field mapping at 850 \(\mu\)m and 450 \(\mu\)m of the z = 2.85 protocluster in the HS 1549+19 field using the Submillimetre …
  33. Radiation Transport Simulations of Quasiperiodic Eruptions from Star–Disk Collisions

    Publication
    Periodic collisions between a star on an inclined orbit around a supermassive black hole and its accretion disk offer a promising explanation for X-ray "quasiperiodic eruptions" (QPEs …
  34. The Life and Times of Star-forming Cores: An Analysis of Dense Gas in the STARFORGE Simulations

    Publication
    Dense gas in molecular clouds is an important signature of ongoing and future star formation. We identify and track dense cores in the STARFORGE simulations, following the core …
  35. Prospects for Observing Astrophysical Transients with Gigaelectronvolt Neutrinos

    Publication
    Although Cherenkov detectors of high-energy neutrinos in ice and water are often optimized to detect teraelectronvolt–petaelectronvolt neutrinos, they may also be sensitive to transient neutrino sources …
  36. HIP 8522: A Puzzling Young Solar Twin with the Lowest Detected Lithium

    Publication
    We present HIP 8522, a young solar twin with the lowest detected lithium, potentially a field blue straggler or the result of episodic early accretion. Its stellar parameters …
  37. Linking Stellar Populations to H II Regions across Nearby Galaxies. II. Infrared Reprocessed and UV Direct Radiation Pressure in H II Regions

    Publication
    Radiation pressure is a key mechanism by which stellar feedback disrupts molecular clouds and drives H II region expansion. This includes direct radiation pressure exerted by UV photons …
  38. Search for Continuous Gravitational Waves from Known Pulsars in the First Part of the Fourth LIGO-Virgo-KAGRA Observing Run

    Publication
    Continuous gravitational waves (CWs) emission from neutron stars carries information about their internal structure and equation of state, and it can provide tests of general relativity. We present …
  39. Aggressively Dissipative Dark Dwarfs: The Effects of Atomic Dark Matter on the Inner Densities of Isolated Dwarf Galaxies

    Publication
    We present the first suite of cosmological hydrodynamical zoom-in simulations of isolated dwarf galaxies for a dark sector that consists of cold dark matter and a strongly …
  40. An Obliquity Measurement of the Hot Neptune TOI-1694b

    Publication
    We present spectral observations of the multiplanet host TOI-1694 during the transit of TOI-1694b, a 26.1 M\(_{\oplus}\) hot Neptune with a 3.77 day …
  41. Cosmological limits on the neutrino mass sum for beyond-\(\Lambda\)CDM models

    Publication
    The sum of neutrino masses can be measured cosmologically, as the sub-eV particles behave as "hot" dark matter whose main effect is to suppress the clustering of …
  42. New particle pusher with hadronic interactions for modeling multimessenger emission from compact objects

    Publication
    We propose novel numerical schemes based on the Boris method in curved spacetime, incorporating both hadronic and radiative interactions for the first time. Once the proton has lost …
  43. Axion pulsarscope

    Publication
    Electromagnetic fields surrounding pulsars may source coherent ultralight axion signals at the known rotational frequencies of the neutron stars, which can be detected by laboratory experiments (e.g …
  44. Boosting H I-galaxy cross-clustering signal through higher order cross-correlations

    Publication
    After reionization, neutral hydrogen (\({\rm H\, {\small I}}\)) traces the large-scale structure (LSS) of the Universe, enabling \({\rm H\, {\small I}}\) intensity mapping (IM) to capture the …
  45. JWST Observations of Starbursts: Cold Clouds and Plumes Launching in the M82 Outflow

    Publication
    In this paper we study the filamentary substructure of 3.3 \(\mu\)m PAH emission from JWST/NIRCam observations in the base of the M82 star-burst driven …
  46. A field-level emulator for modelling baryonic effects across hydrodynamic simulations

    Publication
    We develop a new and simple method to model baryonic effects at the field level relevant for weak lensing analyses. We analyse thousands of state-of-the-art …
  47. The formation, evolution, and disruption of star clusters with improved gravitational dynamics in simulated dwarf galaxies

    Publication
    So far, even the highest resolution galaxy formation simulations with gravitational softening have failed to reproduce realistic life cycles of star clusters. We present the first star-by …
  48. Disentangling the Galaxy's Gordian knot: evidence from APOGEE–Gaia for a knotted and slower bar in the Milky Way

    Publication
    The inner \(\sim 5\) kiloparsec (kpc) region of the Milky Way is complex. However, unravelling the evolution of the Galaxy requires precise understanding of the formation of this …
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