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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Fake Light Workshop

    Workshop
    With exciting new JWST data arriving every day, it is an ideal time to think about directly comparing galaxy formation models with JWST observations. This focused invitation-only …
  2. Developmental Dynamics Group Meeting

    Meeting
  3. Bayes Reading Group: Ryan Giordano (MIT)

    Meeting
    Discussion Lead: Ryan Giordano (MIT) Topic: Black Box Variational Inference with a Deterministic Objective: Faster, More Accurate, and Even More Black Box Abstract: Automatic differentiation variational inference (ADVI …
  4. CCN Seminar with Iris Stone

    Seminar
    Flatiron Institute community members are cordially invited to a CCN Seminar with Iris Stone, Postdoctoral Associate, Pillow Lab, Princeton University, taking place TODAY, Thursday, May 25 from 11 …
  5. The Search for Fundamental Rules Underlying How Microbiomes Are Constructed

    Lecture
    An appreciation of the size and scope of microbiomes creates new curiosities: How do these cells interact in generating complex functions that affect their host organisms? Understanding the …
  6. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  7. CCB Seminar: Exploring the wave nature of life across scales - from active matter to ecology (Tom Shimizu, Ph.D., AMOLF)

    Meeting
    Speaker: Tom Shimizu, Ph.D., AMOLF Topic: Exploring the wave nature of life across scales – from active matter to ecology Viewed at sufficiently large scales, the dynamics of …
  8. Max Planck-New York Center for Nonequilibrium Quantum Phenomena: Spring Meeting 2023

    Conference
  9. Structural & Molecular Biophysics Group Meeting

    Event
  10. Genomics Group Meeting

    Meeting
  11. Biophysical Modeling Group Meeting

    Meeting
  12. NAIG Group Meeting with Julia Wang

    Seminar
    Speaker: Julia Wang PhD Candidate, Cold Spring Harbor Laboratory Title: “Characterizing brain state heterogeneity with an interpretable manifold” Abstract: Brain states are conventionally divided into wake, slow wave …
  13. Developmental Dynamics Group Meeting

    Meeting
  14. Cosmic Connections: A ML X Astrophysics Symposium

    Symposia
    May 22, 2023 Cosmic Connection: Day 1, Session 1 May 22, 2023 Cosmic Connections: Day 1, Session 2 May 22, 2023 Cosmic Connections: Day 1, Session 3 May …
  15. Cosmic Connections: a Symposium to Explore the Intersection of Astrophysics and Machine Learning

    Workshop
    The symposium aims to bring together machine learning researchers and astrophysicists to discuss what are the most interesting astrophysical challenges and where state-of-the-art machine learning …
  16. GRC: Modulation of Neural Circuits and Behavior
    Mechanisms that Underlie Flexible Neural Coding

    Related
    This conference will focus on how brains adjust information processing and optimize behaviors in response to ever-changing environmental demands. This astonishing flexibility relies on the modulation of …
  17. Modulation of Neural Circuits and Behavior (GRS): Integrating Diverse Approaches to Understand Neural Mechanisms of Behavior

    Related
    The aim of this seminar is to bring together outstanding young scientists with a keen interest in neural underpinnings of behavior. The focus of the seminar is to …
  18. CCA Colloquium: Evan Schneider

    Event
    CCA Colloquium: Evan Schneider Title: Galaxy Simulations in the Era of Exascale Abstract: Recent years have witnessed enormous gains in the complexity of astrophysics simulations, and the computational …
  19. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  20. CCN Seminar with Adrien Peyrache (McGill)

    Seminar
    Flatiron Institute community members are cordially invited to a CCN Seminar with Adrien Peyrache, Associate Professor, Montreal Neurological Institute and Hospital at McGill University. To schedule a meeting …
  21. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  22. Genomics Group Meeting

    Meeting
  23. CCM Colloquium: Alessandro Laio SISSA (Italy)

    Event
    Speaker: Alessandro Laio (SISSA) Title: Identifying informative distance measures in high-dimensional feature spaces Real-world data in biochemistry, material science and beyond typically contain a large number …
  24. Structural & Molecular Biophysics Group Meeting

    Event
  25. Biophysical Modeling Group Meeting

    Meeting
  26. SCDG/SCS special tutorial: Marco Barbone (Imperial)

    Meeting
    Practical HPC: vectorization, branch avoidance, and modern C++ tricks. Marco is a grad student in CS at Imperial College, London. He is a contributor to our FINUFFT code …
  27. Developmental Dynamics Group Meeting

    Meeting
  28. Polaron Meeting

    Workshop
    Monday, May 15 2:00 – 2:45 PM Peter Littlewood (University of Chicago) Polaron Physics and “Quantum Paraelectricity” in SRTIO3 2:45-3:30 PM David Reichman (Columbia …
  29. A Space to Dance

    In Conversation
    … musical A Strange Loop (Lyceum Theatre, premiered off-Broadway at Playwrights Horizon). He was hailed by The New York Times as the choreographer who “can make your …
  30. Squeezing Quantum Uncertainty by Entangling Atoms

    Lecture
    Quantum uncertainty hampers the precision of state-of-the-art measurements of time, magnetic fields, acceleration and gravity. Pushing these measurements to their ultimate limits requires engineering entanglement …
  31. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  32. CCM Colloquium: Jingfang Huang (UNC Chapel Hill)

    Event
    Speaker: Jingfang Huang (UNC Chapel Hill) Title: On the Algebraic Structure of Layer and Volume Potentials In this talk, we study the algebraic structures of the Laplace layer …
  33. Machine Learning at the Flatiron Institute Talks: Eero Simoncelli

    Event
  34. Structural & Molecular Biophysics Group Meeting

    Event
  35. CCQ Quantum Cafe with Renata Wentzcovitch

    Colloquium
    Title: Spin crossovers in iron in mantle phases May 9, 2023 Renata Wentzcovitch: Spin crossovers in iron in mantle phases
  36. Biophysical Modeling Group Meeting

    Meeting
  37. Developmental Dynamics Group Meeting

    Meeting
  38. Athena++ Workshop

    Workshop
    … will implicitly attest to being symptom/COVID free. Vaccination status will no longer be validated as a condition of entry. However, all staff and affiliates are strongly …
  39. MPS Conference on Higher Dimensional Geometry, May 8-12, 2023

    Conference
    … boundedness of klt singularities Donaldson and Sun showed that singularities on Gromov-Hausdorff limits of Kähler-Einstein Fano manifolds have algebraic metric tangent cones, and they conjectured …
  40. CCA Colloquium: Charlie Conroy

    Event
    CCA Colloquium: Charlie Conroy Title: TBD Abstract: TBD
  41. CCA Colloquium: Charlie Conroy

    Event
    CCA Colloquium: Charlie Conroy Title: Assembling our Galaxy Abstract: The standard cosmological model predicts that our Galaxy has been sculpted by the hierarchical assimilation of many smaller galaxies …
  42. Bayes Reading Group: Stefan Radev (Heidelberg University)

    Meeting
    Discussion Lead: Stefan Radev(Heidelberg University) Topic: JANA: Jointly Amortized Neural Approximation of Complex Bayesian Models Abstract: This work proposes “jointly amortized neural approximation” (JANA) of intractable likelihood …
  43. Seminar Flatiron Institute Seminar Series: Lisa Brown

    Seminar
    Title: My History of Computer Vision: From Early Neural Nets to Boosting to Activity Recognition Abstract: In the first half of the talk, I will describe the history …
  44. The How and Why of Sleep

    Lecture
    Sleep is a fundamental biological process, and its disruption profoundly impacts human health. In this lecture, Yang Dan will describe her team’s effort to identify neurons involved …
  45. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  46. CCM Colloquium: Jeremy Hoskins (University of Chicago)

    Event
  47. Machine Learning at the Flatiron Institute Seminar: David Hogg

    Seminar
    Title: Is good machine learning bad for science? Abstract: ML is now baked into many scientific projects. I give two example contexts in which even very well-trained …
  48. ML@Fl: David Hogg (CCA)

    Event
    Please join us for a meeting of the Machine Learning at the Flatiron Institute Journal Club with David Hogg. David’s talk will take place in the CCN …
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