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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Machine Learning at the Flatiron Institute Seminar: David Hogg

    Event
    Title: Is good machine learning bad for science? Abstract: ML is now baked into many scientific projects. I give two example contexts in which even very well-trained …
  2. SIMBA Collaboration Meeting

    Meeting
    … ratios in quiescent galaxies – Kate Whitaker 3:15-3:45  Coffee break 3:45-4:10  Cosmic Evolution of Atomic and Molecular Gas within Dark Matter Halos …
  3. Machine Learning Talks

    Colloquium
  4. CCQ Current and Past Quantum Cafe Schedules

    Colloquium
  5. CCQ Workshop Schedule 2023

    Workshop
  6. CCA Colloquium: Ylva Gotberg

    Event
    CCA Colloquium: Ylva Gotberg Title: The discovery and properties of binary-stripped helium stars Abstract: Massive stars stripped of their H-rich envelopes through mass transfer or common …
  7. Machine Learning at the Flatiron Institute Seminar: Laure Zanna

    Event
    Title: Machine learning for climate modeling Abstract: Climate simulations remain one of the best tools to understand and predict global and regional climate change. Yet, these simulations demand …
  8. Bayes Reading Group: Samuel Livingstone

    Meeting
    Discussion Lead: Samuel Livingstone Topic: The Barker proposal: Combining robustness and efficiency in gradient‐based MCMC Abstract: There is a tension between robustness and efficiency when designing Markov …
  9. CCB Colloquium: Locomotion of Flagellated Bacteria: The Influence of Complex Fluids and the Role of Multiflagellarity (Xiang Chen, Ph.D., University of Minnesota)

    Colloquium
    … drag on their larger bodies. Without such a collective balancing mechanism, the swimming speed of uniflagellar bacteria generically decreases with increasing body size. As such, our study …
  10. Waves Inside Stars: The Beauty and Power of Asteroseismology

    Lecture
    Space asteroseismology — the study of waves inside stars using space-based telescopes — saw its birth less than two decades ago, yet it has already revolutionized our understanding of …
  11. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  12. Multiscale Mechanobiology Journal Club

    Meeting
  13. CCM Colloquium: Grady Wright (tentative)

    Event
  14. Machine Learning at the Flatiron Institute Seminar: Dmitri Kochkov

    Seminar
    Title: Numerical methods + ML for simulation of turbulent systems Abstract: Simulations of turbulent flows are routinely used in fundamental research and have numerous practical applications such as climate …
  15. Machine Learning at the Flatiron Institute Seminar: Dmitrii Kochkov

    Event
    Title: Numerical methods + ML for simulation of turbulent systems Abstract: Simulations of turbulent flows are routinely used in fundamental research and have numerous practical applications such as climate …
  16. EMIG Seminar: Three CryoEM stories: discovery of a new pathogen, escaping pseudosymmetry traps, and limitations to resolution (Jason Kaelber, Ph.D., Rutgers University)

    Meeting
    Speaker: Jason Kaelber, Rutgers University Title: Three CryoEM stories: discovery of a new pathogen, escaping pseudosymmetry traps, and limitations to resolution. To crack a nationwide pandemic in farmed …
  17. Genomics Group Meeting

    Meeting
  18. Biophysical Modeling Group Meeting

    Meeting
  19. CCN Seminar with Eli Sennesh (Northeastern)

    Lecture
    Flatiron Institute community members are cordially invited to a CCN Seminar with Eli Sennesh, PhD student at Northeastern University. To schedule an appointment with Eli, please contact Jessica …
  20. Developmental Dynamics Group Meeting

    Meeting
  21. Computational and Theoretical Zebrafish Neuroscience

    Related
    This workshop aims to provide a community-building forum for researchers at all career stages interested in the interface between zebrafish neuroscience and computation to come together, share …
  22. CCA Colloquium: Kaitlin Kratter

    Event
    CCA Colloquium: Kaitlin Kratter Title: The origins of planets and the stars they orbit. Abstract: A satisfying theory for star or planet formation should not consider these processes …
  23. Bayes Reading Group: Yuling Yao

    Meeting
    Discussion Lead: Yuling Yao [CCM] Topic: Computation and evaluation without the likelihood—Or did you forget to compute it? Abstract: Both computation and model-evaluation become hard when …
  24. NCA Group Meeting with Konstantin Mischaikow (Rutgers)

    Lecture
    Konstantin Mischaikow (Rutgers) will be presenting to the group. If you would like to meet with Professor Mischaikow while he is visiting, please be in touch with Jessica …
  25. CCB Brown Bag Seminar

    Meeting
    Speaker: Gilles Francfort, Ph.D., Research Scientist Topic: The role of stability in macroscopic solids with defects This is meant to be a short narration of the efforts …
  26. Seminar Flatiron Institute Seminar Series: Alex Williams

    Seminar
    Title: Tensor decompositions reveal neural signatures of cognitive and behavioral state changes Abstract: Perceptions, thoughts, and actions unfold over millisecond timescales, while learned behaviors can require many days …
  27. How the Human Microbiome Adapts to Its Host

    Lecture
    The microbes that live on and inside us play a surprisingly significant role in our health and the progression of diseases. But the human microbiome is not static …
  28. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  29. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  30. Genomics Group Meeting

    Meeting
  31. CCM Colloquium: Qing Qu (University of Michigan)

    Event
  32. Machine Learning at the Flatiron Institute Seminar: Tammy Kolda

    Seminar
    Title: Generalized tensor decomposition: Utility for data analysis and mathematical challenges Abstract: Tensor decomposition is an unsupervised learning methodology that has applications in a wide variety of domains …
  33. Machine Learning at the Flatiron Institute Seminar: Tammy Kolda

    Event
    Title: Generalized tensor decomposition: Utility for data analysis and mathematical challenges Abstract: Tensor decomposition is an unsupervised learning methodology that has applications in a wide variety of domains …
  34. Biophysical Modeling Group Meeting

    Meeting
  35. Developmental Dynamics Group Meeting

    Meeting
  36. ‘Fire Of Love’ — Meet the Director

    In Conversation
    … boundary-breaking documentaries rooted in scientific ideas that inform society and culture. Harrop is a hands-on executive producer. Her credits include “Fire of Love” (nominated for …
  37. CCA Colloquium: Pedro Espino

    Event
    CCA Colloquium: Pedro Espino Title: Constraining high-density deconfinement phase transitions with gravitational wave spectroscopy of binary neutron star mergers Abstract: The determination of the state of matter …
  38. Bayes Reading Group: Trevor Campbell [University of British Columbia]

    Meeting
    Discussion Lead: Trevor Campbell [University of British Columbia] Topic: MixFlows: Principled Variational Bayesian Inference via Approximately Measure-Preserving Maps Abstract: This talk will introduce mixed variational flows (MixFlows …
  39. IBRO-Simons Computational Neuroscience Imbizo

    SCGB
    The IBRO-Simons Computational Neuroscience Imbizo, or isiCNI is an opportunity for African and international students to learn about cutting edge research techniques in computational neuroscience. The format …
  40. 2023 MathBioSys Annual Meeting

    Conference
    … 13, 2023 Carole LaBonne | Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions April 14, 2023 William Kath | Quantifying dynamical changes and statistics of …
  41. Making Quantum States of Light With Moving Mirrors

    Lecture
    Over the last few decades, experimental physicists have observed quantum effects in the vibrations of mechanical resonators in a surprising range of experiments and sizes of objects. Achieving …
  42. Systems Biology Group Meeting

    Meeting
  43. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The first open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize. Come and chat with developers and users about where things are, and …
  44. CCM Colloquium: Jonathan Weare (NYU)

    Event
  45. Machine Learning at the Flatiron Institute Seminar: Laure Zanna

    Seminar
    Title: Machine learning for climate modeling Abstract: Climate simulations remain one of the best tools to understand and predict global and regional climate change. Yet, these simulations demand …
  46. Genomics Group Meeting

    Meeting
  47. CCQ Quantum Cafe with Andrea Cavalleri

    Colloquium
    Title: Advances in Optically Driven Cuprate Superconductivity April 11, 2023 Andrea Cavalleri: Advances in Optically Driven Cuprate Superconductivity
  48. Biophysical Modeling Group Meeting

    Meeting
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