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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Neuroscience 2017: Presentations by SFARI Investigators

    October 25, 2017
    A selection of presentations that will be given by past and current SFARI Investigators at Neuroscience 2017 in Washington, D.C., (November 11–15) is highlighted.
  2. Join the Science Sandbox Community

    October 23, 2017
    Science Sandbox launches a newsletter and other new ways to connect.
  3. Whole-Exome Sequencing of SPARK: New Data Release

    October 20, 2017
    SPARK (Simons Foundation Powering Autism Research for Knowledge) is pleased to announce that whole-exome sequencing (WES) and genotyping data are available for 1,369 and 1,398 …
  4. Science Sandbox Enters Partnership With Sundance Institute

    October 20, 2017
    Led by Sundance Institute’s Documentary Film Program, the new initiative offers grants and other opportunities for emerging nonfiction filmmakers seeking to explore the intrinsic link between science …
  5. Five Winning Science Everywhere Teachers Are Announced

    October 18, 2017
    As part of a campaign to bring science and math outside the classroom, five teachers each win $5,000 for submitting innovative projects
  6. Pixelated Movies Yield Faster Way To Image Many Neurons

    October 18, 2017
    New analysis techniques can process calcium-imaging data and other types of visual information faster and enable researchers to track larger numbers of neurons.
  7. A Star That Devoured Its Own Planets

    October 12, 2017
    Astrophysicists estimate that the sunlike star called Kronos has consumed 15 Earths’ worth of rocky material
  8. Sabbatical Visiting Researcher Program – Center for Computational Astrophysics

    October 12, 2017
    The Center for Computational Astrophysics (CCA) at the Simons Foundation’s Flatiron Institute invites researchers on sabbatical to visit the CCA in 2018–2019. Located in New York …
  9. Watch: The World’s Smallest Science Museum

    October 11, 2017
    In this video, Science Sandbox spotlights MICRO, a team of innovators bringing the science museum experience to unexpected places.
  10. Stepping Out of Museums and Into Communities

    October 11, 2017
    By meeting people in their communities, Ben Wiehe and Just Add Science are challenging the core principles of traditional science engagement.
  11. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    October 11, 2017
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  12. Shafi Goldwasser Appointed Director of the Simons Institute for the Theory of Computing

    October 10, 2017
    … More than 1,000 visiting scientists have participated in the institute’s semester-long research programs exploring foundational questions in data science, machine learning, evolutionary biology, quantum …
  13. Spike Sorting Becomes Fully Automated

    October 6, 2017
    A potentially game-changing algorithm eliminates manual sorting in the analysis of neural signals.
  14. Mathematician Alex Barnett Joins CCB as Leader of Numerical Algorithms Group

    October 3, 2017
    The Flatiron Institute is delighted to announce that Alex Barnett has joined the Center for Computational Biology (CCB) as group leader for the Numerical Algorithms group. Barnett is …
  15. The Eternal Sky, Part 2: The Hunt for Inflation

    October 3, 2017
    The Simons Observatory will offer insights into the origins of the universe. Second in a series.
  16. 2018 Pilot and Research Award Applications: The Review Process

    October 2, 2017
    This blog post accompanies the “SFARI’s 2018 funding priorities” post. In it, the SFARI science team discusses the application and review process for 2018 Pilot and Research …
  17. SFARI’s 2018 Funding Priorities

    October 2, 2017
    In this blog post, the SFARI science team provides insight into SFARI’s scientific priorities. A number of experimental design issues to consider when preparing a grant application …
  18. Watch: Werner Herzog on Science Sandbox

    October 1, 2017
    The Science Sandbox Advisory Board reacts to the team’s mission
  19. Watch: Vikki Spruill on Science Sandbox

    October 1, 2017
    The Science Sandbox Advisory Board reacts to the team’s mission
  20. Watch: Rob Lue on Science Sandbox

    October 1, 2017
    The Science Sandbox Advisory Board reacts to the team’s mission
  21. Watch: Miranda July on Science Sandbox

    October 1, 2017
    The Science Sandbox Advisory Board reacts to the team’s mission
  22. New Dataset Explores Neuronal Basis of Behavior

    September 26, 2017
    Researchers used computer vision and machine learning to create a comprehensive database linking specific circuits in the fruit fly brain to behavior.
  23. Flatiron Scientists — With Help From the Public — Study Connection Between Body Bacteria and Autoimmune Disease

    September 26, 2017
    IBM’s World Community Grid has teamed up with the Flatiron Institute, Broad Institute of MIT and Harvard, Massachusetts General Hospital and the University of California, San Diego.
  24. Meet the Science Sandbox @ New Lab Fellows

    September 25, 2017
    Science Sandbox launches a fellowship at Brooklyn’s New Lab designed to develop new projects that connect science, technology and research to society
  25. Embracing the Difficult: Scientific Controversies at Pioneer Works

    September 22, 2017
    Astrophysicist Janna Levin hosts frank — and sometimes contentious — conversations in an interdisciplinary Brooklyn warehouse space.
  26. Green Algae Could Hold Clues for Engineering Faster Growing Crops

    September 21, 2017
    … other Rubiscos. The result is a clump of Rubiscos and EPYC1s that form a liquid-like droplet. The change in the system’s phase depending on the …
  27. Virtual Brain Lab Brings Together Leading Neuroscientists Across the World

    September 19, 2017
    … project, its emphasis on data sharing and a focus on a single behaviour will help to move the field of neuroscience forward by illustrating how many labs …
  28. New SFARI Gene Website Launched

    September 18, 2017
    The SFARI Gene website has been redesigned. The updated platform features a streamlined user interface and new data visualizations, which were engineered with the aim of making it …
  29. A Conversation With Sharmila Banerjee-Basu About SFARI Gene

    September 18, 2017
    Sharmila Banerjee-Basu, founder and chief scientific officer at MindSpec Inc., discusses SFARI Gene and how it is changing the face of autism genetics research.
  30. A New Look for the Simons Foundation Website

    September 13, 2017
    An esthetic and mobile-friendly update also incorporates new sections and functional changes, all to better carry out the foundation’s mission.
  31. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    September 13, 2017
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  32. A New Effort To Standardize Neurophysiology Data

    September 11, 2017
    Neurodata Without Borders wants to transform the field by making it easier to share research.
  33. Using Artificial Intelligence to Map the Brain’s Wiring

    September 11, 2017
    Neuroscientist Sebastian Seung has pioneered the use of machine learning to construct dense neural wiring diagrams from high-resolution imaging.
  34. Simons Collaboration on the Global Brain Announces Awardees to Explore the Brain’s Hidden States

    September 7, 2017
    The new grants focus on larger collaborations, with teams of up to 20 investigators employing a range of technologies and statistical tools.
  35. Gov. Andrew Cuomo Joins Jim and Marilyn Simons to Dedicate Flatiron Institute

    September 7, 2017
    The new institute drives scientific discovery using computational methods.
  36. Flatiron Institute Dedication Ceremony (Video)

    September 7, 2017
    Updated September 22, 2017, with new video. New York Gov. Andrew Cuomo and Simons Foundation co-founders Jim and Marilyn Simons dedicated the Flatiron Institute on September 6 …
  37. Astrophysicist Yuri Levin Heads CCA’s New Compact Objects Research Group

    September 1, 2017
    … Cosmology and Gravitational Wave Astronomy groups at the Flatiron Institute, located across the street from the Simons Foundation headquarters in New York City.
  38. Research Center Established to Explore the Least Understood and Strongest Forces Behind Visible Matter

    August 30, 2017
    Stony Brook University and Brookhaven National Lab launch the Center for Frontiers in Nuclear Science.
  39. On the Homepage: Earth’s Phytoplankton

    August 24, 2017
    The image in the blue homepage area shows dominant phytoplankton types during the period 1994-1998, as determined from a high-resolution ocean and ecosystem model. Colors represent …
  40. Whole-genome sequencing of the Simons Simplex Collection: New data release

    August 22, 2017
    Whole-genome sequencing data for a total of 8,975 genomes from the Simons Simplex Collection are now available. This includes 2,174 genomes that have been available …
  41. Simons Variation in Individuals Project (Simons VIP): New data release

    August 18, 2017
    New Simons VIP Phase 2 data have recently been added to SFARI Base. This data release includes phenotypic data from individuals with 16p11.2 copy number variants (CNVs …
  42. From the bioRxiv: A Selection of Recently Posted Papers from SCGB Investigators and Others

    August 14, 2017
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  43. In Fruit Fly Brain, A Ring for Navigation

    August 1, 2017
    The neurons that keep track of a fly’s position follow the rules of a ring attractor network, new research shows.
  44. New Initiative Ponders Origins of the Universe

    July 21, 2017
    The Simons Foundation effort will develop testable predictions about string theory, quantum gravity and a cosmological ‘Big Bounce.’
  45. Remembering the Life and Contributions of Fields Medalist Maryam Mirzakhani

    July 20, 2017
    Mathematician’s work broke new ground in geometry
  46. Tired Worms Suggest Sleep Is an Emergent Property of Neural Networks

    July 19, 2017
    Monitoring neural activity across the entire brain in worms as they drift into slumber could bring insight into the purpose of sleep.
  47. Face Recognition Relies on Surprisingly Simple Code

    July 17, 2017
    Face-processing neurons seem to use linear algebra, representing faces as vectors in a 50-dimensional vector space.
  48. Foundation Announces Simons Collaboration on Arithmetic Geometry, Number Theory and Computation

    July 13, 2017
    The Simons Foundation is pleased to announce the establishment of the Simons Collaboration on Arithmetic Geometry, Number Theory and Computation, directed by Brendan Hassett of Brown University. The …
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