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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. CCB Short Course: Intro to Information Theory in Biology

    Meeting
    Lecturer: Henry Mattingly, Associate Research Scientist, Biophysical Modeling In the 1940s, Claude Shannon invented information theory, afundamental tool for quantifying statistical uncertainty andinference. The fact that it deals …
  2. Genomics Group Meeting

    Meeting
  3. Biophysical Modeling Group Meeting

    Meeting
  4. Developmental Dynamics Group Meeting

    Meeting
  5. CCA Colloquium: Edit-a-thon

    Event
    CCA Colloquium: Edit-a-thon In lieu of our usual colloquium next Friday, we’ll be having a fun internal event: the first ever CCA wiki edit-a …
  6. From the Human Microbiome Project to the Earth Microbiome Project

    Lecture
    The Human Microbiome Project drove an explosion of technologies aimed at understanding the vast array of microbes present throughout our bodies. The resulting ability to scale up DNA …
  7. Systems Biology Group Meeting

    Meeting
  8. CCB Short Course: Intro to Information Theory in Biology

    Meeting
    Lecturer: Henry Mattingly, Associate Research Scientist, Biophysical Modeling In the 1940s, Claude Shannon invented information theory, afundamental tool for quantifying statistical uncertainty andinference. The fact that it deals …
  9. Genomics Group Meeting

    Meeting
  10. Machine Learning at the Flatiron Institute Seminar: Chirag Mod

    Seminar
    Title: Reconstructing the initial conditions of the Universe Abstract: Over the last decade, cosmologists have been exploring a novel way of analyzing survey data by reconstructing the Gaussian …
  11. Structural & Molecular Biophysics Group Meeting

    Event
  12. Biophysical Modeling Group Meeting

    Meeting
  13. Lectures on Diagrammatic Monte Carlo: Low-rank Representation of Imaginary-time Green’s function (Kun Chen)

    Lecture
    … Exchange-correlation effects in a warm dense electron gas (Pengcheng Hou); January 24, 2023: Study of the real frequency dependence of the optical conductivity in the 2D …
  14. Machine Learning at the Flatiron Institute Seminar: Chirag Modi

    Event
    Title: Reconstructing the initial conditions of the Universe February 6, 2023 Chirag Modi: Reconstructing the Initial Conditions of the Universe
  15. Developmental Dynamics Group Meeting

    Meeting
  16. CCA Colloquium: Eiichiro Komatsu

    Event
    CCA Colloquium: Eiichiro Komatsu Title: The Temperature of Hot Gas in the Universe Abstract: How hot is the Universe today? How hot was it before? In this talk …
  17. CCN Seminar with John Pearson (Duke University)

    Seminar
    You are cordially invited to a CCN Seminar with John Pearson, Assistant Professor of Biostatistics & Bioinformatics, Duke University. To set up a meeting with John while he is …
  18. CCB Seminar: Natalie Sauerwald, Ph.D, Flatiron Research Fellow (Genomics)

    Meeting
    Speaker: Natalie Sauerwald, Ph.D. Flatiron Research Fellow (Genomics) Title: Analysis frameworks for sequencing data Next generation sequencing (NGS), the revolutionary technology that allows for the rapid and …
  19. 2023 Simons Collaboration on the Theory of Algorithmic Fairness Annual Meeting

    Conference
    … Christos Tzamos. February 2, 2023 Jon Kleinberg | The Challenge of Understanding What Users Want: Inconsistent Preferences and Engagement Optimization February 2, 2023 Bailey Flanigan | Accounting for Stakes …
  20. The Quantum Revolution: Emerging Technologies at the Atomic Scale

    Lecture
    Traditional electronics are rapidly approaching the length scale of atoms and molecules; the latest computer chips in development include transistors the size of a single strand of DNA …
  21. CCQ Current and Past Quantum Cafe Schedules

    Colloquium
  22. Structural & Molecular Biophysics Group Meeting

    Event
  23. Genomics Group Meeting

    Meeting
  24. Biophysical Modeling Group Meeting

    Meeting
  25. Quantum Geometry Working Group

    Workshop
    Informal working group on the topic of quantum geometry, with a focus on moire materials. Tuesday, January 31 9:30 – 10:30am Eslam Khalad Charged excitations in ideal …
  26. Developmental Dynamics Group Meeting

    Meeting
  27. CCA-KITP Joint Workshop

    Workshop
    … 2023 Short Talks – Robert Feldmann, Megan Tillman, Festa Bucinca and Yu-Heng Lin February 2, 2023 Review Talk – Henry Ferguson: Applications of Machine Learning for Studying Galaxy …
  28. CCN Seminar with Srdjan Ostojic (ENS)

    Seminar
    You are cordially invited to a CCN Seminar with Srdjan Ostojic To set up a meeting with Srdjan, please reach out to Jessica Hauser at [email protected] …
  29. Gothamfest 2023

    Conference
    COVID Policy: By making entry to our buildings all staff, vendors and guests will implicitly attest to being symptom/COVID free. Vaccination status will no longer be validated …
  30. Dynamical Systems Journal Club

    Lecture
    At Dynamical Systems Journal Club this week, Alexander Bogatskii will present on Hamiltonian Fields from Chapter 14 in Applied Nonlinear Dynamical Systems by Stephen Wiggins.
  31. CCB Seminar: Wilson Bennett Lough (UW-Madison)

    Meeting
    Speaker: Wilson Bennett Lough, UW–Madison Research, teaching and outreach in Physics Title: Self-buckling and self-writhing of semi-flexible microorganisms Multi-flagellated microorganisms can buckle and …
  32. Systems Biology Group Meeting

    Meeting
  33. CCB Short Course: Intro to Information Theory in Biology

    Meeting
    Lecturer: Henry Mattingly, Associate Research Scientist, Biophysical Modeling In the 1940s, Claude Shannon invented information theory, afundamental tool for quantifying statistical uncertainty andinference. The fact that it deals …
  34. Genomics Group Meeting

    Meeting
  35. Structural & Molecular Biophysics Group Meeting

    Event
  36. Biophysical Modeling Group Meeting

    Meeting
  37. Lectures on Diagrammatic Monte Carlo: Study of the real frequency dependence of the optical conductivity in the 2D Hubbard model (Maxence Grandadam)

    Lecture
    … Exchange-correlation effects in a warm dense electron gas (Pengcheng Hou); January 24, 2023: Study of the real frequency dependence of the optical conductivity in the 2D …
  38. 2023 Cross-Species Studies of ASD RFA — Informational session

    Webinar
    On January 23, 2023, SFARI hosted an informational session on the 2023 Cross-Species Studies of ASD request for applications (RFA).
  39. Flatiron Institute Seminar Series: Phil Armitage

    Seminar
    Title: What we don’t know about planet formation Abstract: It has long been known that planets form from dust and gas in the protoplanetary disks that are …
  40. CCB Brown Bag Seminar

    Meeting
    Speaker: Vikram Mulligan, Ph.D., Research Scientist, Systems Biology Topic: Next-generation software for heteropolymer design and structure prediction For decades, the Rosetta software suite has been one …
  41. 2023 Simons Collaboration on Ultra Quantum Matter Annual Meeting

    Conference
    … gapped states, such as topological orders and fractons, as well as gapless states including novel metallic phases and the realization of such states particularly in synthetic quantum …
  42. Systems Biology Group Meeting

    Meeting
  43. Structural & Molecular Biophysics Group Meeting

    Event
  44. Genomics Group Meeting

    Meeting
  45. Biophysical Modeling Group Meeting

    Meeting
  46. CCB Colloquium: Pratyush Tiwary, Ph.D. (University of Maryland)

    Colloquium
    Speaker: Pratyush Tiwary, Ph.D., Associate Professor, University of Maryland-College Park
  47. Systems Biology Group Meeting

    Meeting
  48. 2023 Simons Collaboration on Arithmetic Geometry, Number Theory, and Computation Annual Meeting

    Conference
    … Galois of an elliptic curve over Q), and then highlight several new ideas from the joint work, including techniques for computing models of modular curves and novel …
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