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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Automated assessment of mouse behavioral modules

    January 30, 2016
    Sandeep Robert Datta describes a combined 3D computer vision/machine-learning method that identifies behavioral modules expressed by freely behaving mice.
  2. SFARI announces Novel Outcome Measures for ASD Clinical Trials awardees

    January 29, 2016
    SFARI is pleased to announce that it has awarded four grants in response to the Novel Outcome Measures for ASD Clinical Trials request for applications. These grants will …
  3. SFARI announces Novel Outcome Measures for ASD Clinical Trials awardees

    January 29, 2016
    This issue of the SFARI newsletter includes: (1) SFARI announces Novel Outcome Measures for ASD Clinical Trials awardees, (2) SFARI-funded publications.
  4. Song Learning in Birds Shown to Depend on Recycling of Neural Signals

    January 27, 2016
    A study details the motor-neuron mechanisms that underlie learning and singing in zebra finches.
  5. SFARI announces Functional Screen of Autism-Associated Variants awardees

    January 15, 2016
    This issue of the SFARI newsletter includes: (1) SFARI announces Functional Screen of Autism-Associated Variants awardees, (2) SFARI Blog: Making sense out of missense mutations.
  6. SFARI announces Functional Screen of Autism-Associated Variants awardees

    January 12, 2016
    SFARI is pleased to announce that it has awarded five grants in response to the Functional Screen of Autism-Associated Variants request for applications. These grants will support …
  7. Making sense out of missense mutations

    January 12, 2016
    SFARI launched a request for applications in early 2015 that sought proposals to develop medium- and high-throughput screens to test the functional effects of de novo missense …
  8. Science Lives: Mathematician Ronald Graham (1935–2020)

    January 11, 2016
    Ron Graham is an American mathematician who is known for his work in scheduling theory, computational geometry, Ramsey theory, quasi-randomness and juggling.
  9. MPS Awardee Spotlight: Eliot Quataert

    December 17, 2015
    … from, what our place in the universe is. People are really excited and engaged by those questions.”
  10. Whole-Genome Analysis of the Simons Simplex Collection (SSC)

    December 11, 2015
    SFARI is pleased to announce that it has awarded five grants in response to the Whole-Genome Analysis for Autism Risk Variants request for applications. We are also …
  11. Whole-genome analysis of the Simons Simplex Collection (SSC)

    December 11, 2015
    This issue of the SFARI newsletter includes: (1) SFARI announces Whole-Genome Analysis for Autism Risk Variants awardees, (2) Availability of whole-genome sequencing data from the Simons …
  12. Inaugural Conference of the Simons Collaboration on Homological Mirror Symmetry

    December 11, 2015
    … counting. K. Costello discussed higher genus instanton corrections to the mirror correspondence from the point of view of BCOV quantization. There were complementary talks by mathematicians (Efimov …
  13. New Erdős Paper Solves Egyptian Fraction Problem

    December 10, 2015
    Nearly 20 years after his death, the famed mathematician Paul Erdős keeps on publishing, thanks to the conjectures he left behind and the friends who strive to prove …
  14. Wikipedia Year of Science

    December 7, 2015
    December 2015 – Present
  15. SFARI 2015 Pilot and Research awardees announced

    December 4, 2015
    SFARI is pleased to announce that it has awarded 28 grants (15 Pilot Awards and 13 Research Awards) in response to the 2015 Pilot and Research Awards request …
  16. SFARI announces 2015 Pilot and Research awardees

    December 4, 2015
    This issue of the SFARI newsletter includes: (1) SFARI 2015 Pilot and Research awardees announced, (2) Autism BrainNet and NIH NeuroBioBank partner to advance autism research, (3) SFARI …
  17. Global Brain Meeting Explores the Puzzle of Cognition

    December 3, 2015
    The inaugural meeting of the Simons Collaboration on the Global Brain reviewed the progress made in understanding the neural basis of memory, decision making and behavior The inaugural …
  18. Global Brain Meeting Explores the Puzzle of Cognition

    December 1, 2015
    The inaugural meeting of the Simons Collaboration on the Global Brain reviewed the progress made in understanding the neural basis of memory, decision making and behavior
  19. The Simons Collaboration on the Global Brain Meeting Agenda

    November 25, 2015
    … Churchland and Abbott labs) Dynamics of Neural Coordination Across Hemispheres Xiaoyin Chen, Ph.D. (Cold Spring Harbor Laboratory, Zador lab) The Role of Corticostriatal Neurons in Visual …
  20. Autism BrainNet and NIH NeuroBioBank partner to advance autism research

    November 18, 2015
    Simons Foundation and Autism Speaks have entered into an agreement with the National Institutes of Health to align two of the world’s largest repositories of donated postmortem …
  21. Autism BrainNet and NIH NeuroBioBank Partner to Advance Autism Research

    November 18, 2015
    … much-needed replication of published findings.” Adds Daniel Smith, Autism Speaks’ vice president for innovation technologies: “This important partnership arms autism researchers with a higher quality resource …
  22. Breakthrough Prizes Awarded to 4 Simons Investigators

    November 10, 2015
    … million each. Larry Guth of the Massachusetts Institute of Technology won a New Horizons in Mathematics Prize, which carries with it an award of $100,000. More …
  23. David Spergel To Lead New Center for Computational Astrophysics

    November 9, 2015
    … and serve as a focal point for computational astronomy around the world. David Spergel is the Charles A. Young Professor of Astronomy on the Class of 1897 …
  24. Detailed Galaxy Maps Offer Clues to Cosmic Mysteries

    November 5, 2015
    Boris Leistedt of the Simons Society of Fellows blends statistics and cosmology to grapple with the nature of dark matter and dark energy
  25. Celebrating the Life and Work of John F. Nash, Jr.

    October 24, 2015
    … connection with the 2015 Abel Prize. (Used by the Simons Foundation with permission.) Click to be taken to the Nov. 27, 2011, Science Lives interview.
  26. MPS Awardee Spotlight: Laura DeMarco

    October 21, 2015
    … other fields and connecting subjects that people didn’t know were related is one of the most rewarding experiences.” Variation of Canonical Height Torsion points on an …
  27. Neuroscience 2015: Presentations by SFARI Investigators

    October 16, 2015
    Lectures and symposium presentations that will be given by SFARI Investigators at Neuroscience 2015 in Chicago (17-21 October 2015) are highlighted.
  28. Foundation Announces the First Targeted Grants in MPS Awardees

    October 16, 2015
  29. Big Data Tool to Reveal Immune System Role in Diseases

    September 30, 2015
    Researchers from the Genomics group of the Simons Center for Data Analysis, the Icahn School of Medicine at Mount Sinai and Princeton University have designed a new online …
  30. DNA Diversity Studies Trace Ancient Human Migrations

    September 29, 2015
    The human tendency to wander, mingle and mate has left its marks on our DNA. Geneticist David Reich is uncovering those clues in order to determine how our …
  31. Thought-Controlled Technology Improves Thanks to Motor Cortex Findings

    September 25, 2015
    A new understanding of how motor neurons fire should lead to a dramatic increase in performance of brain-machine interfaces. A new understanding of how motor neurons fire …
  32. BRAIN Initiative Funding Opportunity: Theories, Models and Methods for Analysis of Complex Data from the Brain

    September 18, 2015
    … here. Questions, including potential project aims, can be directed to: [email protected].
  33. Tracking the Ocean’s Circadian Rhythm

    September 17, 2015
    A Simons Foundation collaborative expedition aims to understand the daily interactions of the organisms at the base of the marine food chain
  34. Harnessing Hippocampal Stem Cells to Improve Mood and Cognition

    September 16, 2015
    … plasticity may contribute to neurologic or psychiatric disorders. One way to begin to address this question is to link the functions of adult-born hippocampal neurons with …
  35. Thought-Controlled Technology Improves Thanks to Motor Cortex Findings

    September 10, 2015
    A new understanding of how motor neurons fire should lead to a dramatic increase in performance of brain-machine interfaces
  36. Visual Computation Workshop Defines Goals for Toolbox Development

    September 9, 2015
    … spanned a range of complex mathematical models and components of the visual system, ultimately the goal was simple: to get the researchers’ perspectives on how to make …
  37. SFARI 2016 grants cycle: choices, challenges, and priorities

    August 31, 2015
    Today, we’re announcing our annual request for applications (RFA) for SFARI Pilot and Research Awards. Letters of intent (LOIs), the short statements that precede full applications, are …
  38. New Simons Collaborations: Homological Mirror Symmetry and It From Qubit: Quantum Fields, Gravity, and Information

    August 5, 2015
    … reconciling the laws of quantum mechanics and of gravitation. Perspectives gained from two decades of study of terrestrial quantum phenomena, in particular the recognition of the importance …
  39. 2015 Klingenstein-Simons Fellowship Awards in the Neurosciences Announced

    August 4, 2015
    … Institute of Technology “Neural dynamics supporting the integration of prior knowledge and sensory evidence in cortical circuits” https://mcgovern.mit.edu/principal-investigators/mehrdad-jazayeri http://bcs …
  40. Campus Inauguration Event: Science at ICTS

    August 3, 2015
    … waves and numerical relativity, as well as string theory, particle physics and cosmology. ICTS hosts programs and conferences that bring together outstanding scientists to work on the …
  41. The Pleasure (and Necessity) of Finding Things Out

    August 3, 2015
    The reasons for doing basic research go well beyond the creation of new applications and technologies
  42. Marathon Editing Brings New Rigor to Wikipedia Physics

    July 28, 2015
    In the Simons Foundation’s first Wikipedia edit-a-thon, dozens of physicists spend a morning mass-editing the online encyclopedia
  43. Autism Risk Genes: Success with the Simplex Approach

    July 27, 2015
    Studies of simplex families — those that have only one member with autism, rather than multiple members — are providing details of the disorder’s genetic basis
  44. Studying the Ocean’s Microbiome

    July 20, 2015
    A collaboration looking at the micro-organisms in the seas aims to enhance our understanding of ocean processes and ecology
  45. MPS Awardee Spotlight: Bruce Kleiner

    July 16, 2015
    … Kleiner. Bruce Kleiner, New York University Bruce Kleiner, a principal investigator in the Simons Collaboration on Algorithms and Geometry, was also a 2014 Simons Fellow in Mathematics …
  46. Math Boot Camp Prepares U.S. Team for International Mathematical Olympiad

    July 13, 2015
    The Mathematical Olympiad Summer Program teaches students problem-solving techniques that will serve them throughout their mathematical careers
  47. Solving the “Many Electron” Problem

    July 13, 2015
    The behavior of electrons dictates the properties of materials, but characterizing all their complex interactions has often proved impossible. A concerted effort aims to break that intractability
  48. Simons Award for Graduate Students in TCS (featured block)

    July 9, 2015
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