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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. SAND Group Meeting with Ching Fang & Emily Mackevicius

    Lecture
    This week’s SAND lab meeting will feature Ching Fang (PhD student) and Emily Mackevicius (Postdoc) from Columbia. They will give back-to-back presentations on their recent …
  2. CCB Summer Interns Poster Session

    Meeting
  3. Genomics Group Meeting

    Meeting
  4. CCB Seminar: Fragment-Based Ligand Generation Guided By Geometric Deep Learning On Protein-Ligand Structure (Helen Yu, Ph.D., Stanford University)

    Meeting
    Speaker: Helen Yu, Ph.D., Stanford University Topic: Fragment-Based Ligand Generation Guided By Geometric Deep Learning On Protein-Ligand Structure Computationally-aided design of novel molecules has …
  5. Developmental Dynamics Group Meeting

    Meeting
  6. Biophysical Modeling Group Meeting

    Meeting
  7. How Emotions Shape Our Memories

    In Conversation
    … was on the faculty of Caltech. In addition to many pioneering academic research papers, he has written for The New York Times, The Wall Street Journal, Scientific …
  8. CCM Colloquium: Elvis Dohmatob (Facebook)

    Event
    Elvis Dohmatob (Facebook AI Research) Title: Tradeoffs between test error and robustness in different learning regimes for two-layer neural networks Abstract: Neural networks are known to be …
  9. Methods in Computational Neuroscience

    Related
    MCN introduces students to the computational and mathematical techniques that are used to address how the brain solves problems at levels of neural organization ranging from single membrane …
  10. Developmental Dynamics Group Meeting

    Meeting
  11. Biophysical Modeling Group Meeting

    Meeting
  12. NWB User Days 2022

    Related
    The Neurodata Without Borders project (NWB, nwb.org) is an effort to standardize the description and storage of neurophysiology data and metadata. NWB enables data sharing and reuse …
  13. Mechanisms for Superconductivity

    Conference
    … Pseudopotential: Two Wrongs Make a “Right” July 27, 2022 Jörg Schmalian: Controlled large-N approach to quantum-critical superconductivity
  14. CCB Seminar: Sensing transcription factors in the fly embryo (Marianne Bauer, Ph.D., Delft University of Technology)

    Meeting
    Speaker: Marianne Bauer, Ph.D., Delft University of Technology Topic: Sensing transcription factors in the fly embryo Transcription factor concentrations can be seen as signals that need to …
  15. VJC: Kendrick Kay

    Event
    Currently, Nikhil, Robert Roodry from NYU and Jing Yang Zhou are organizing vision journal club on a bi-weekly basis (in-person at NYU and on zoom, 4pm …
  16. CCB Seminar: Altered protein dynamics and transition kinetics delineate oncogenic potential in mutated kinases (Ravi Radhakrishnan, Ph.D, University of Pennsylvania)

    Meeting
    … protein dynamics to validate our model. Our enhanced atomistic simulations are a significant improvement over unbiased molecular dynamics techniques to study protein dynamics and transition kinetics and …
  17. Genomics Group Meeting

    Meeting
  18. Electron Microscopy Interest Group Meeting

    Meeting
    Speakers: Jake D. Johnston, New York Structural Biology Center Reza Paraan, New York Structural Biology Center
  19. Developmental Dynamics Group Meeting

    Meeting
  20. Biophysical Modeling Group Meeting

    Meeting
  21. CAJAL Computational Neuroscience Summer Course

    Related
    The course teaches the central ideas, methods, and practices of modern computational neuroscience through a combination of lectures and hands-on project work. During the course’s mornings …
  22. Metabolism, Aging, Pathogenesis, and Stress in C. elegans

    Related
    The 2022 C. elegans “Topics” Meeting “Metabolism, Aging, Pathogenesis, and Stress” (MAPS 2022), on campus at the University of Wisconsin-Madison, Memorial Union will host researchers studying fundamental …
  23. Developmental Dynamics Group Meeting

    Meeting
  24. Biophysical Modeling Group Meeting

    Meeting
  25. Neuromatch Academy (NMA) 2022

    Lecture
    Neuromatch Academy teaches computational techniques crucial for success in academia and industry. It serves thousands of students each year with hundreds of teaching assistants. Students learn by solving …
  26. FENS Forum 2022

    Related
    Europe’s largest international neuroscience conference, covering all domains in modern brain research from basic to translational research.
  27. Flatiron Institute Seminar Series: Simon Trebst

    Seminar
    Title: Quantum Computing “al dente” Abstract: From the perspective of many-body physics, the transmon qubit architecture currently developed for quantum computing in scalable platforms by IBM, Google …
  28. Genomics Group Meeting

    Meeting
  29. Genomics Group Meeting

    Meeting
  30. CCB Seminar: Hydronamics of slender swimmers near deformable interfaces (Sankalp Nambiar, Nordic Institute for Theoretical Physics)

    Meeting
    Speaker: Sankalp Nambiar, Nordic Institute for Theoretical Physics Title: Hydrodynamics of slender swimmers near deformable interfaces We study the coupled hydrodynamics between a motile slender microswimmer and a …
  31. SFARI 2022 Genomics of ASD: Pathways to Biological Convergence and Genetic Therapies RFA — Informational session

    Webinar
    On July 5, 2022, SFARI hosted an informational session on the 2022 Genomics of ASD: Pathways to Biological Convergence and Genetic Therapies request for applications (RFA). The session …
  32. Genomics Group Meeting

    Meeting
  33. CCB Seminar: Weight loss dependent and independent effects of bariatric surgery (Danny Beh-Ziv, Hebrew University of Jersualem)

    Meeting
    Speaker: Danny Beh-Zvi, The Hebrew University of Jerusalem Topic: Weight loss dependent and independent effects of bariatric (weight loss) surgery Bariatric, AKA weight-loss surgery, is an …
  34. LCV Lab Meeting: Eric Wu, Stanford University

    Event
    Please join us on June 29th for our LCV Group meeting with our guest speaker, Eric Wu, Stanford University presenting: Title: “Maximum a posteriori natural scene reconstruction from …
  35. CCB Seminar: Ciliary control of chromosomal pairing mechanics in meiosis, and cellular control of phase-separation in oocyte polarity – two tales, common cellular machinery (Yaniv Elkouby, Hebrew University of Jersualem)

    Meeting
    … microscopy, molecular, and biochemical evidence to show that Bb granules initially undergo liquid-liquid phase separation, and then gradually lipid-solid phase- separation in forming the mature …
  36. Electron Microscopy Interest Group Meeting

    Meeting
    Are you interested in electron microscopy? Do you use or analyze cryo-electron- tomography data? Are you developing methods for single particle analysis? Have you just started studying …
  37. CCN Seminar: E.J. Chichilinsky

    Event
    Please welcome our CCN Seminar guest speaker E.J. Chichilinsky who will be presenting, “Replicating the Neural Code: Toward a High-Fidelity Artificial Retina” in our CCN Classroom …
  38. N-Body Workshop

    Workshop
    Attendee Instructions: Registration required. Please email Abigail Creem for Zoom information. Remote participation will NOT be available for the tutorial session on June 27th, June 28th, and July …
  39. Developmental Dynamics Group Meeting

    Meeting
  40. Biophysical Modeling Group Meeting

    Meeting
  41. Labels and Lab Coats: Exploring Science Identity

    In Conversation
    … artist. His art is inspired by societal dynamics and interpersonal relationships, often taking the form of unconventional or surreal portraits. Aya Osman is a behavioral neuroscientist, science …
  42. 2022 Pre-Doc Symposium

    Symposia
    The pre-doc symposium will highlight the work of our Spring 2022 pre-doc class. This event will take place Friday, June 24th from 1-4:30pm in …
  43. CCA Colloquium: Hiranya Peiris

    Event
    CCA Colloquium: Hiranya Peiris Title: Prospects for understanding the physics of the Universe Abstract: The remarkable progress in cosmology over the last decades has been driven by the …
  44. Genomics Group Meeting

    Meeting
  45. 8th Annual BRAIN Initiative Meeting: Open Science, New Tools

    Related
    The BRAIN Initiative® Meeting convenes BRAIN Initiative awardees, staff, and leadership from the contributing federal agencies (NIH, NSF, DARPA, IARPA, and FDA), plus representatives and investigators from …
  46. 2022 Many Electron Collaboration Summer School

    Conference
    … PM Moire Materials: Metal-insulator transitions and superconductivity | Andy Millis
  47. CCB Seminar: "Massive Linear Swimmers at Low Reynolds Number"" (Oleg Trosman, Friedrich-Alexander University Erlangen-Nuremberg)

    Seminar
    Massive Linear Swimmers at Low Reynolds Number Two possibilities of description of swimmers’ motion, the stroke-based as well as the force-based one, are showcased, both of …
  48. CCB Seminar: "Machine Learning Strategies for Alternate Splicing" (Zhicheng Pan, UCLA)

    Seminar
    … of 8,304 samples across 53 tissues from the GTEx project. We demonstrate that iDARTS can help to identify the causal effects of common and rare genomic …
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